Patents by Inventor Agnes Fogo

Agnes Fogo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Classifying and predicting glomerulosclerosis using a proteomics approach
    Publication number: 20060223122
    Abstract: The present invention provides for a proteomic approach to classifying glomerular tissue as normal, non-sclerotic or sclerotic. In particular, the proteomic approach may employ laser capture microdissection followed by MALDI-TOF. A particular target of interest that is highly relevant in distinguishing such tissues is thymosin ?4.
    Type: Application
    Filed: March 8, 2006
    Publication date: October 5, 2006
    Inventors: Agnes Fogo, Richard Caprioli
  • Method and compositions for maintaining glomerular filtration rate while inhibiting extracellular matrix accumulation
    Patent number: 6531482
    Abstract: This invention provides a method of and compositions for increasing or maintaining glomerular filtration rate while preserving renal structure in a patient comprising administering an angiotensin II type 1 vascular receptor antagonist to the patient, independent of its effects on systemic blood pressure. The invention provides that, by administering the AII type 1 receptor antagonist, blood flow to the kidney can be improved without sacrificing intraglomerular pressure and therefore glomerular filtration and that even with this enhanced glomerular pressure and filtration, renal structure is preserved.
    Type: Grant
    Filed: April 4, 2000
    Date of Patent: March 11, 2003
    Assignee: Vanderbilt University
    Inventors: Valentina Kon, Agnes Fogo, Iekuni Ichikawa
  • Method and compositions for maintaining glomerular filtration rate while inhibiting extracellular matrix accumulation
    Patent number: 5677312
    Abstract: This invention provides a method of and compositions for increasing or maintaining glomerular filtration rate while preserving renal structure in a patient comprising administering an angiotensin II type 1 vascular receptor antagonist to the patient, independent of its effects on systemic blood pressure. The invention provides that, by administering an AII type 1 receptor antagonist, blood flow to the kidney can be improved without sacrificing intraglomerular pressure and therefore glomerular filtration and that even with this enhanced glomerular pressure and filtration, renal structure is preserved.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: October 14, 1997
    Assignee: Vanderbilt University
    Inventors: Valentina Kon, Agnes Fogo, Iekuni Ichikawa
  • Method of screening of angiotens in II type I receptor antagonists
    Patent number: 5660813
    Abstract: This invention provides a method of and compositions for increasing or maintaining glomerular filtration rate while preserving renal structure in a patient comprising administering an angiotensin II type 1 vascular receptor antagonist to the patient, independent of its effects on systemic blood pressure. The invention provides that, by administering an AII type 1 receptor antagonist, blood flow to the kidney can be improved without sacrificing intraglomerular pressure and therefore glomerular filtration and that even with this enhanced glomerular pressure and filtration, renal structure is preserved.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: August 26, 1997
    Assignee: Vanderbilt University
    Inventors: Valentina Kon, Agnes Fogo, Iekuni Ichikawa
  • Method and compositions for maintaining glomerular filtration rate while inhibiting extracellular matrix accumulation
    Patent number: 5512580
    Abstract: This invention provides a method of and compositions for increasing or maintaining glomerular filtration rate while preserving renal structure in a patient comprising administering an angiotensin II type 1 vascular receptor antagonist to the patient, independent of its effects on systemic blood pressure. The invention provides that, by administering the AII type 1 receptor antagonist, blood flow to the kidney can be improved without sacrificing intraglomerular pressure and therefore glomerular filtration and that even with this enhanced glomerular pressure and filtration, renal structure is preserved.
    Type: Grant
    Filed: July 25, 1994
    Date of Patent: April 30, 1996
    Assignee: Vanderbilt University
    Inventors: Valentina Kon, Agnes Fogo, Iekuni Ichikawa
  • Treatment of chronic kidney disease with angiotensin I converting enzyme inhibitor
    Patent number: 5071867
    Abstract: A method of healing extracellular matrix degradation to reverse glomerular sclerosis includes the steps of administering on angiotension I converting enzyme inhibitor and suppressing extracellular matrix release independent of the blood pressure effects of the enzyme inhibitor.
    Type: Grant
    Filed: February 28, 1990
    Date of Patent: December 10, 1991
    Assignee: Vanderbilt University
    Inventors: Iekuni Ichikawa, Agnes Fogo, Masaaki Ikoma, Tetsuya Kawamura