Patents by Inventor Agnes Tempez
Agnes Tempez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10361075Abstract: A system and a process for measuring, by glow discharge spectrometry, the elemental and/or molecular chemical composition of an organic solid sample (10). The sample (10) is positioned so as to seal a glow discharge plasma reactor (2), a gaseous mixture including at least one inert gas and gaseous oxygen is injected into the reactor (2), the concentration of gaseous oxygen being between 0.1% and 15% by weight of the gaseous mixture, an electric discharge of radiofrequency type is applied to the electrodes of the plasma reactor (2) in order to generate a glow discharge plasma, and the solid sample (10) is exposed to the plasma so as to etch an erosion crater in the solid sample (10); at least one signal representative of an ionized species of negative charge is selected and measured using a mass spectrometer (4).Type: GrantFiled: March 27, 2015Date of Patent: July 23, 2019Assignee: HORIBA JOBIN YVON SASInventors: Patrick Chapon, Agnes Tempez, Sebastien Legendre
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Publication number: 20170018417Abstract: A system and a process for measuring, by glow discharge spectrometry, the elemental and/or molecular chemical composition of an organic solid sample (10). The sample (10) is positioned so as to seal a glow discharge plasma reactor (2), a gaseous mixture including at least one inert gas and gaseous oxygen is injected into the reactor (2), the concentration of gaseous oxygen being between 0.1% and 15% by weight of the gaseous mixture, an electric discharge of radiofrequency type is applied to the electrodes of the plasma reactor (2) in order to generate a glow discharge plasma, and the solid sample (10) is exposed to the plasma so as to etch an erosion crater in the solid sample (10); at least one signal representative of an ionized species of negative charge is selected and measured using a mass spectrometer (4).Type: ApplicationFiled: March 27, 2015Publication date: January 19, 2017Applicant: Horiba Jobin Yvon SASInventors: Patrick CHAPON, Agnes TEMPEZ, Sebastien LEGENDRE
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Patent number: 8581494Abstract: A glow discharge spectrometer discharge lamp includes: a lamp body having a vacuum enclosure connected to pump elements and to injector elements for injecting an inert gas into the enclosure; a hollow cylindrical first electrode of longitudinal axis X-X?; a second electrode for receiving a sample for analysis and for holding the sample facing one end of the cylindrical electrode; electric field generator including an applicator for applying to the terminals of the electrodes an electric field that is continuous, pulsed, radiofrequency, or hybrid, and suitable for generating a glow discharge plasma in the presence of the gas; coupler elements for coupling the discharge lamp to a spectrometer suitable for measuring at least one component of the plasma; and magnetic field generator elements for generating a magnetic field having field lines oriented along the axis X-X?, the magnetic field being uniform in orientation and in intensity over an area of the sample that is not less than the inside area of the hollowType: GrantFiled: February 10, 2010Date of Patent: November 12, 2013Assignee: Horiba Jobin Yvon SASInventors: Mihai Ganciu-Petcu, Virgil Mircea Udrea, Agnes Tempez, Patrick Chapon
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Patent number: 8581180Abstract: The present invention relates to a device for measuring glow discharge spectrometry in pulsed mode, which includes an RF electric field generator in pulsed mode, a discharge lamp, an impedance matching device for transferring the electric power supplied by the generator to the discharge lamp and a mass spectrometer suitable for measuring at least one signal representative of an ionised plasma species. According to the invention, the device includes a measurement system suitable for measuring a signal representative of the impedance mismatch ?? between the generator and the discharge lamp, said measurement system including a fast acquisition system, synchronized with the pulses and suitable for supplying the impedance matching device with a signal representing the impedance mismatch ?? for at least one part of said pulses. The device enables continuous impedance adaptation.Type: GrantFiled: April 14, 2011Date of Patent: November 12, 2013Assignee: Horiba Jobin Yvon SASInventors: Patrick Chapon, Olivier Rogerieux, Agnes Tempez
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Publication number: 20130200257Abstract: The present invention relates to a device for measuring glow discharge spectrometry in pulsed mode, which includes an RF electric field generator in pulsed mode, a discharge lamp, an impedance matching device for transferring the electric power supplied by the generator to the discharge lamp and a mass spectrometer suitable for measuring at least one signal representative of an ionised plasma species. According to the invention, the device includes a measurement system suitable for measuring a signal representative of the impedance mismatch ?? between the generator and the discharge lamp, said measurement system including a fast acquisition system, synchronized with the pulses and suitable for supplying the impedance matching device with a signal representing the impedance mismatch ?? for at least one part of said pulses. The device enables continuous impedance adaptation.Type: ApplicationFiled: April 14, 2011Publication date: August 8, 2013Applicant: HORIBA JOBIN YVON SASInventors: Patrick Chapon, Olivier Rogerieux, Agnes Tempez
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Patent number: 8129675Abstract: The content of the invention comprises a concept of reactor for isolated ion transformations induced by collisions with neutral species. This reactor is also an interface between mobility cell and orthogonal injection TOFMS based on supersonic adiabatic gas flow with variable controlled composition directed along the axis of a multipole ion guide with sectioned rods for possibility of creating of controlled distributions of RF, DC and AC rotating fields.Type: GrantFiled: June 12, 2009Date of Patent: March 6, 2012Assignee: Ionwerks, Inc.Inventors: J. Albert Schultz, Valeriy V. Raznikov, Thomas F. Egan, Michael V. Ugarov, Agnès Tempez, Marina O. Raznikova, Vladislav V. Zelenov, Alexander R. Pikhtelev, Valerie E. Vaughn
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Patent number: 8115167Abstract: The content of the invention comprises a concept of multi-beam ion pre-selection from a single sample, coordinated mobility (against the gas flow) separation, cooling ions in supersonic gas flow and mass separation of thus low divergent ions by single or plural compact high-resolution orthogonal time-of-flight mass spectrometers both linear or reflectron type with controlled collision-induced dissociation (CID) and multi-channel data recording for the optimization of sample use in the analysis, and obtaining as much useful information about the sample as possible in a reasonably short time.Type: GrantFiled: December 18, 2008Date of Patent: February 14, 2012Assignee: Ionwerks, Inc.Inventors: Valeri V. Raznikov, J. Albert Schultz, Thomas F. Egan, Michael V. Ugarov, Agnès Tempez, Gennadiy Savenkov, Vladislav Zelenov
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Publication number: 20110291567Abstract: A glow discharge spectrometer discharge lamp includes: a lamp body having a vacuum enclosure connected to pump elements and to injector elements for injecting an inert gas into the enclosure; a hollow cylindrical first electrode of longitudinal axis X-X?; a second electrode for receiving a sample for analysis and for holding the sample facing one end of the cylindrical electrode; electric field generator including an applicator for applying to the terminals of the electrodes an electric field that is continuous, pulsed, radiofrequency, or hybrid, and suitable for generating a glow discharge plasma in the presence of the gas; coupler elements for coupling the discharge lamp to a spectrometer suitable for measuring at least one component of the plasma; and magnetic field generator elements for generating a magnetic field having field lines oriented along the axis X-X?, the magnetic field being uniform in orientation and in intensity over an area of the sample that is not less than the inside area of the hollowType: ApplicationFiled: February 10, 2010Publication date: December 1, 2011Applicant: HORIBA JOBIN YVON SASInventors: Mihai Ganciu-Petcu, Virgil Mircea Udrea, Agnes Tempez, Patrick Chapon
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Publication number: 20100090101Abstract: The present invention enhances the laser desorption of biological molecular ions from surfaces by creating a surface localized MALDI particle matrix by ion implantation of low energy ionized clusters (gold, aluminum, etc.) or chemically derivatized clusters into the near surface region of the sample. MALDI analysis of the intact biomolecules on the surface or within a narrow subsurface region defined by the implantation range of the ions can then be performed by laser desorption into a mass spectrometer or, in a preferred embodiment, into a combined ion mobility orthogonal time of flight mass spectrometer.Type: ApplicationFiled: December 4, 2009Publication date: April 15, 2010Applicant: Ionwerks, Inc.Inventors: J. Albert Schultz, Michael V. Ugarov, Thomas F. Egan, Agnes Tempez, Yvon Le Bayec, Serge Della-Negra
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Publication number: 20090309015Abstract: The content of the invention comprises a concept of reactor for isolated ion transformations induced by collisions with neutral species. This reactor is also an interface between mobility cell and orthogonal injection TOFMS based on supersonic adiabatic gas flow with variable controlled composition directed along the axis of a multipole ion guide with sectioned rods for possibility of creating of controlled distributions of RF, DC and AC rotating fields.Type: ApplicationFiled: June 12, 2009Publication date: December 17, 2009Inventors: J. Albert Schultz, Valeriy V. Raznikov, Thomas F. Egan, Michael V. Ugarov, Agnes Tempez, Marina O. Raznikova, Vladislav V. Zelenov, Alexander R. Pikhtelev, Valerie E. Vaughn
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Patent number: 7629576Abstract: The present invention enhances the laser desorption of biological molecular ions from surfaces by creating a surface localized MALDI particle matrix by ion implantation of low energy ionized clusters (gold, aluminum, etc.) or chemically derivatized clusters into the near surface region of the sample. MALDI analysis of the intact biomolecules on the surface or within a narrow subsurface region defined by the implantation range of the ions can then be performed by laser desorption into a mass spectrometer or, in a preferred embodiment, into a combined ion mobility orthogonal time of flight mass spectrometer.Type: GrantFiled: September 21, 2005Date of Patent: December 8, 2009Assignee: Ionwerks, Inc.Inventors: J. Albert Schultz, Michael V. Ugarov, Thomas F. Egan, Agnes Tempez, Yvon Le Beyec, Serge D. Negra
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Patent number: 7547878Abstract: The content of the invention comprises a concept of reactor for isolated ion transformations induced by collisions with neutral species. This reactor is also an interface between mobility cell and orthogonal injection TOFMS based on supersonic adiabatic gas flow with variable controlled composition directed along the axis of a multipole ion guide with sectioned rods for possibility of creating of controlled distributions of RF, DC and AC rotating fields.Type: GrantFiled: June 29, 2007Date of Patent: June 16, 2009Assignee: Ionwerks, Inc.Inventors: J. Albert Schultz, Valeriy V. Raznikov, Thomas F. Egan, Michael V. Ugarov, Agnès Tempez, Marina O. Raznikova, Vladislav V. Zelenov, Alexander R. Pikhtelev, Valerie E. Vaughn
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Publication number: 20090140140Abstract: The content of the invention comprises a concept of multi-beam ion pre-selection from a single sample, coordinated mobility (against the gas flow) separation, cooling ions in supersonic gas flow and mass separation of thus low divergent ions by single or plural compact high-resolution orthogonal time-of-flight mass spectrometers both linear or reflectron type with controlled collision-induced dissociation (CID) and multi-channel data recording for the optimization of sample use in the analysis, and obtaining as much useful information about the sample as possible in a reasonably short time.Type: ApplicationFiled: December 18, 2008Publication date: June 4, 2009Inventors: Valeri V. Raznikov, J. Albert Schultz, Thomas F. Egan, Michael V. Ugarov, Agnes Tempez, Gennadiy Savenkov, Vladislav Zelenov
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Patent number: 7482582Abstract: The content of the invention comprises a concept of multi-beam ion pre-selection from a single sample, coordinated mobility (against the gas flow) separation, cooling ions in supersonic gas flow and mass separation of thus low divergent ions by single or plural compact high-resolution orthogonal time-of-flight mass spectrometers both linear or reflectron type with controlled collision-induced dissociation (CID) and multi-channel data recording for the optimization of sample use in the analysis, and obtaining as much useful information about the sample as possible in a reasonably short time.Type: GrantFiled: May 26, 2006Date of Patent: January 27, 2009Assignee: Ionwerks, Inc.Inventors: Valeri V. Raznikov, J. Albert Schultz, Thomas F. Egan, Michael V. Ugarov, Agnès Tempez, Gennadiy Savenkov, Vladislav Zelenov
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Patent number: 7429729Abstract: The present invention relates generally to instrumentation and methodology for the characterization of chemical samples in solutions or on a surface which is based on modified ionization methods with or without adjustable pH and controllable H-D exchange in solution, in improved ion mobility spectrometer (IMS), a multi-beam ion per-selection of the initial flow, and coordinated mobility and mass ion separation and detection using a single or several independent time-of-flight mass spectrometers for different beams with methods for fragmenting ion mobility-separated ions and multi-channel data recording.Type: GrantFiled: May 26, 2006Date of Patent: September 30, 2008Assignee: Ionwerks, Inc.Inventors: J. Albert Schultz, Valeri V. Raznikov, Thomas F. Egan, Michael V. Ugarov, Agnès Tempez, Marina O. Raznikova, Valentin A. Tarasenko
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Publication number: 20080164409Abstract: The content of the invention comprises a concept of reactor for isolated ion transformations induced by collisions with neutral species. This reactor is also an interface between mobility cell and orthogonal injection TOFMS based on supersonic adiabatic gas flow with variable controlled composition directed along the axis of a multipole ion guide with sectioned rods for possibility of creating of controlled distributions of RF, DC and AC rotating fields.Type: ApplicationFiled: June 29, 2007Publication date: July 10, 2008Inventors: J. Albert Schultz, Valeriy V. Raznikov, Thomas F. Egan, Michael V. Ugarov, Agnes Tempez, Marina O. Raznikova, Vladislav V. Zelenov, Alexander R. Pikhtelev, Valerie E. Vaughn
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Patent number: 7223969Abstract: Improved ion focusing for an ion mobility drift cell allows for improved throughput for subsequent detection such as mass detection. Improved focusing is realized by the use of alternating regions of high and low electric fields in the ion mobility drift cell.Type: GrantFiled: January 30, 2006Date of Patent: May 29, 2007Assignee: Ionwerks, Inc.Inventors: J. Albert Schultz, Valeri Raznikov, Thomas F. Egan, Michael V. Ugarov, Agnès Tempez
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Publication number: 20060289747Abstract: The present invention relates generally to instrumentation and methodology for the characterization of chemical samples in solutions or on a surface which is based on modified ionization methods with or without adjustable pH and controllable H-D exchange in solution, an improved ion mobility spectrometer (IMS), a multi-beam ion pre-selection of the initial flow, and coordinated mobility and mass ion separation and detection using a single or several independent time-of-flight mass spectrometers for different beams with methods for fragmenting ion mobility-separated ions and multi-channel data recordingType: ApplicationFiled: May 26, 2006Publication date: December 28, 2006Applicant: Ionwerks, Inc.Inventors: J. Schultz, Valeri Raznikov, Thomas Egan, Michael Ugarov, Agnes Tempez, Marina Raznikova, Valentin Tarasenko
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Publication number: 20060289746Abstract: The content of the invention comprises a concept of multi-beam ion pre-selection from a single sample, coordinated mobility (against the gas flow) separation, cooling ions in supersonic gas flow and mass separation of thus low divergent ions by single or plural compact high-resolution orthogonal time-of-flight mass spectrometers both linear or reflectron type with controlled collision-induced dissociation (CID) and multi-channel data recording for the optimization of sample use in the analysis, and obtaining as much useful information about the sample as possible in a reasonably short time.Type: ApplicationFiled: May 26, 2006Publication date: December 28, 2006Inventors: Valeri Raznikov, J. Schultz, Thomas Egan, Michael Ugarov, Agnes Tempez, Gennadiy Savenkov, Vladislav Zelenov
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Publication number: 20060192104Abstract: Improved ion focusing for an ion mobility drift cell allows for improved throughput for subsequent detection such as mass detection. Improved focusing is realized by the use of alternating regions of high and low electric fields in the ion mobility drift cell.Type: ApplicationFiled: January 30, 2006Publication date: August 31, 2006Applicant: Ionwerks, Inc.Inventors: J. Schultz, Valeri Raznikov, Thomas Egan, Michael Ugarov, Agnes Tempez