Patents by Inventor Agnieszka Bartoszewicz

Agnieszka Bartoszewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS
    Publication number: 20230348516
    Abstract: This invention is related to novel inhibitors of chitinase-like protein YKL-40 and their therapeutic applications. Such YKL-40 inhibitors are of use as therapeutic agents for the treatment a variety of diseases and disorders, including cancers, inflammation, and pulmonary diseases.
    Type: Application
    Filed: April 28, 2023
    Publication date: November 2, 2023
    Inventors: Wojciech Czestkowski, Marzena Mazur, Przemyslaw Wanat, Gleb Andryianau, Piotr Niedziejko, Michal Kowalski, Mariusz Marek Gruza, Kamil Lisiecki, Piotr Pomaransk, Damian Kusmirek, Diana Papiernik, Katarzyna Drzewicka, Katarzyna Piwowar, Katarzyna Krysztofiak, Jacek Olczak, Adam Golebiowski, Lukasz Krzeminski, Agnieszka Bartoszewicz
  • YKL-40 INHIBITORS AND THEIR THERAPEUTIC APPLICATIONS
    Publication number: 20230278996
    Abstract: Disclosed are novel assays for screening active compounds interfering with interaction between chitinase-like protein YKL-40 and chitin oligomers, as well as interfering with interaction between chitinase-like protein YKL-40 and heparan sulfate. Moreover, disclosed are novel active compounds identified by these assays as inhibitors of chitinase-like protein YKL-40, their therapeutic applications, and their use in biosensors measuring the level of chitinase-like protein YKL-40 in biological samples.
    Type: Application
    Filed: March 3, 2023
    Publication date: September 7, 2023
    Inventors: Lukasz Krzeminski, Wojciech Czestkowski, Marzena Mazur, Gleb Andryianau, Sylwia Olejniczak, Michal Czeslaw Piotrowicz, Robert Koralewski, Elzbieta Pluta, Krzysztof Matyszewski, Michal Kowalski, Barbara Dymek, Rafal Koziel, Jacek Olczak, Adam Golebiowski, Agnieszka Bartoszewicz, Katarzyna Krysztofiak
  • Substituted amino triazoles useful as chitinase inhibitors
    Patent number: 11638707
    Abstract: Disclosed are amino triazole compounds of formula (I). These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
    Type: Grant
    Filed: July 15, 2020
    Date of Patent: May 2, 2023
    Assignee: Molecure S.A.
    Inventors: Marzena Mazur, Gleb Andryianau, Lukasz Joachimiak, Wojciech Czestkowski, Michal Kowalski, Piotr Niedziejko, Sylwia Olejniczak, Krzysztof Matyszewski, Robert Koralewski, Jacek Olczak, Adam Golebiowski, Agnieszka Bartoszewicz
  • SUBSTITUTED AMINO TRIAZOLES USEFUL AS CHITINASE INHIBITORS
    Publication number: 20210015822
    Abstract: Disclosed are amino triazole compounds of formula (I). These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
    Type: Application
    Filed: July 15, 2020
    Publication date: January 21, 2021
    Inventors: Marzena Mazur, Gleb Andryianau, Lukasz Joachimiak, Wojciech Czestkowski, Michal L. Kowalski, Piotr Niedziejko, Sylwia Olejniczak, Krzysztof Matyszewski, Robert Koralewski, Jacek P. Olczak, Adam A. Golebiowski, Agnieszka Bartoszewicz
  • Substituted amino triazoles useful as human chitinase inhibitors
    Patent number: 10538508
    Abstract: Disclosed are amino triazole compounds substituted with a piperidinyl ring that is itself substituted with a heterocyclic ring. These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: January 21, 2020
    Assignee: OncoArendi Therapeutics S.A.
    Inventors: Marzena Mazur, Robert Koralewski, Bartlomiej Borek, Sylwia Olejniczak, Wojciech J. Czestkowski, Michal C. Piotrowicz, Jacek P. Olczak, Adam A. Golebiowski, Agnieszka Bartoszewicz, Elzbieta Maziarz, Michal L. Kowalski
  • SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS
    Publication number: 20190345137
    Abstract: Disclosed are amino triazole compounds substituted with a piperidinyl ring that is itself substituted with a heterocyclic ring. These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
    Type: Application
    Filed: February 15, 2019
    Publication date: November 14, 2019
    Inventors: Marzena Mazur, Robert Koralewski, Bartlomiej Borek, Sylwia Olejniczak, Wojciech J. Czestkowski, Michal C. Piotrowicz, Jacek P. Olczak, Adam A. Golebiowski, Agnieszka Bartoszewicz, Elzbieta Maziarz, Michal L. Kowalski
  • Substituted amino triazoles useful as human chitinase inhibitors
    Patent number: 10208020
    Abstract: Disclosed are amino triazole compounds substituted with a piperidinyl ring that is itself substituted with a heterocyclic ring. These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
    Type: Grant
    Filed: February 28, 2018
    Date of Patent: February 19, 2019
    Assignee: OncoArendi Therapeutics S.A.
    Inventors: Marzena Mazur, Robert Koralewski, Bartlomiej Borek, Sylwia Olejniczak, Wojciech J. Czestkowski, Michal C. Piotrowicz, Jacek P. Olczak, Adam A. Golebiowski, Agnieszka Bartoszewicz, Elżbieta Maziarz, Michal Łukasz Kowalski
  • SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS
    Publication number: 20180258071
    Abstract: Disclosed are amino triazole compounds substituted with a piperidinyl ring that is itself substituted with a heterocyclic ring. These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
    Type: Application
    Filed: February 28, 2018
    Publication date: September 13, 2018
    Inventors: Marzena Mazur, Robert Koralewski, Bartlomiej Borek, Sylwia Olejniczak, Wojciech J. Czestkowski, Michal C. Piotrowicz, Jacek P. Olczak, Adam A. Golebiowski, Agnieszka Bartoszewicz, Elzbieta Maziarz, Michal Lukasz Kowalski
  • Substituted amino triazoles useful as human chitinase inhibitors
    Patent number: 9944624
    Abstract: Disclosed are amino triazole compounds substituted with a piperidinyl ring that is itself substituted with a heterocyclic ring. These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: April 17, 2018
    Assignee: OncoArendi Therapeutics S.A.
    Inventors: Marzena Mazur, Robert Koralewski, Bartlomiej Borek, Sylwia Olejniczak, Wojciech J. Czestkowski, Michał C. Piotrowicz, Jacek P. Olczak, Adam A. Golebiowski, Agnieszka Bartoszewicz, Elżbieta Maziarz, Michał Łukasz Kowalski
  • SUBSTITUTED AMINO TRIAZOLES USEFUL AS HUMAN CHITINASE INHIBITORS
    Publication number: 20170066743
    Abstract: Disclosed are amino triazole compounds substituted with a piperidinyl ring that is itself substituted with a heterocyclic ring. These compounds are inhibitors of acidic mammalian chitinase and chitotriosidase. Also disclosed are methods of using the compounds to treat asthma reactions caused by allergens, as well as acute and chronic inflammatory diseases, autoimmune diseases, dental diseases, neurologic diseases, metabolic diseases, liver diseases, polycystic ovary syndrome, endometriosis, and cancer.
    Type: Application
    Filed: September 2, 2016
    Publication date: March 9, 2017
    Inventors: Marzena Mazur, Robert Koralewski, Bartlomiej Borek, Sylwia Olejniczak, Wojciech J. Czestkowski, Michal C. Piotrowicz, Jacek P. Olczak, Adam A. Golebiowski, Agnieszka Bartoszewicz, Elzbieta Maziarz, Michal Lukasz Kowalski