Patents by Inventor Ah Ruem BAEK

Ah Ruem BAEK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition containing keratin 8 phosphorylation inhibitor for preventing or treating macular degeneration, and method for screening macular degeneration medicine
    Patent number: 10857154
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating macular degeneration containing trametinib or gefitinib, and to a method of screening a therapeutic agent for macular degeneration. The pharmaceutical composition of the present invention is capable of inhibiting the phosphorylation of keratin 8 and the reorganization thereof around nuclei in retinal pigment epithelial cells under oxidative stress conditions, increasing the expression of E-cadherin, and reducing the expression of vimentin, and can thus be efficiently useful for the prevention or treatment of macular degeneration.
    Type: Grant
    Filed: May 18, 2017
    Date of Patent: December 8, 2020
    Assignee: Konkuk University Industrial Cooperation Corp.
    Inventors: Dong-Eun Kim, Ah Ruem Baek
  • Composition for PCR containing a polyethylene glycol-engrafted nano-sized graphene oxide
    Patent number: 10633698
    Abstract: Disclosed are a composition for PCR including polyethylene glycol-engrafted nano-sized graphene oxide (PEG-nGO), the composition for PCR being capable of increasing the efficiency and specificity of PCR and shortening PCR time, and a PCR method using the same.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: April 28, 2020
    Assignee: KONKUK UNIVERSITY INDUSTRIAL COOPERATION CORP
    Inventors: Dong Eun Kim, Hyo Ryoung Kim, Ah Ruem Baek
  • PHARMACEUTICAL COMPOSITION CONTAINING KERATIN 8 PHOSPHORYLATION INHIBITOR FOR PREVENTING OR TREATING MACULAR DEGENERATION, AND METHOD FOR SCREENING MACULAR DEGENERATION MEDICINE
    Publication number: 20190275044
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating macular degeneration containing trametinib or gefitinib, and to a method of screening a therapeutic agent for macular degeneration. The pharmaceutical composition of the present invention is capable of inhibiting the phosphorylation of keratin 8 and the reorganization thereof around nuclei in retinal pigment epithelial cells under oxidative stress conditions, increasing the expression of E-cadherin, and reducing the expression of vimentin, and can thus be efficiently useful for the prevention or treatment of macular degeneration.
    Type: Application
    Filed: May 18, 2017
    Publication date: September 12, 2019
    Applicant: KONKUK UNIVERSITY INDUSTRIAL COOPERATION CORP
    Inventors: Dong-Eun KIM, Ah Ruem BAEK
  • COMPOSITION FOR PCR CONTAINING A POLYETHYLENE GLYCOL-ENGRAFTED NANO-SIZED GRAPHENE OXIDE
    Publication number: 20180155765
    Abstract: Disclosed are a composition for PCR including polyethylene glycol-engrafted nano-sized graphene oxide (PEG-nGO), the composition for PCR being capable of increasing the efficiency and specificity of PCR and shortening PCR time, and a PCR method using the same.
    Type: Application
    Filed: December 1, 2017
    Publication date: June 7, 2018
    Applicant: KONKUK UNIVERSITY INDUSTRIAL COOPERATION CORP
    Inventors: Dong Eun KIM, Hyo Ryoung KIM, Ah Ruem BAEK