Abstract: An orthodontic separator including a substrate including at least one resilient material configured to produce and maintain an outward force for a predetermined time period between adjacent teeth, wherein the substrate includes a plurality of layers including polymer fibers having a fluoride compound incorporated therein or that coats a surface thereof. The plurality of layers is arranged concentrically and configured such that the plurality of layers of the substrate successively dissolve or disintegrate within the predetermined time period when disposed between those adjacent teeth, whereby the separator dissolves or disintegrates.