Abstract: The present invention provides novel intraocular lens compositions comprising a hydroxyl functional acrylic monomerand have a high Abbe number, minimal glistenings, and suitable mechanical properties for small incision delivery.

Abstract: The present invention provides novel intraocular lens compositions comprising a hydroxyl functional acrylic monomerand have a high Abbe number, minimal glistenings, and suitable mechanical properties for small incision delivery.

Abstract: The present invention provides novel intraocular lens compositions comprising a hydroxyl functional acrylic monomer and have a high Abbe number, minimal glistenings, and suitable mechanical properties for small incision delivery.

Abstract: Various embodiments are generally directed to devices and methods for multi-liquid storage and mixing, such as with a medical liquid packaging device (MLPD), for instance. Some embodiments are particularly directed to an MLPD that includes first and second reservoirs that store separate liquids that may be selectively combined prior to administration to a patient. In one or more embodiments, for example, a device for medical liquid packaging may include a first reservoir and a dispensing port with a second reservoir. In a first state, a flow preventer separates the liquid in the first reservoir from the liquid in the second reservoir. Actuation of an actuator, such as by depression of the actuator, dislodges the flow preventer, allowing fluid communication between the first reservoir and the second reservoir.

Abstract: The present invention provides novel intraocular lens compositions comprising a hydroxyl functional acrylic monomer and have a high Abbe number, minimal glistenings, and suitable mechanical properties for small incision delivery.

Abstract: A biocompatible synthetic macromer composition is provided which includes a first polymer having stiffening linkages and at least one amine group, and a second component having at least one amine-reactive group. The biocompatible synthetic macromer composition can be used as an adhesive or sealant in human and/or animal medical applications.

Abstract: Systems and methods are provided for examination and removal of polyps. Using methods and systems of the present disclosure, one can determine whether a polyp is benign or cancerous in situ.

Abstract: An apparatus for forming an anastomosis between adjacent intestinal sections of tissue is provided. The apparatus includes a circular surgical stapler having an anvil assembly with an anvil shaft and an anvil, the circular surgical stapler further having a tubular body portion with an annular knife and a body portion shaft selectively attachable to the anvil shaft; and a seal structure for deposition between the intestinal sections of tissue including a hub configured to engage attachment structure on at least one of the anvil shaft and the body portion shaft. The attachment structure is positioned so that the seal structure is located between the intestinal sections of tissue when the circular surgical stapler is disposed within the intestinal sections of tissue.

Abstract: The present disclosure relates to compositions comprising a copolymer that includes a first monomer and a second monomer that is different from the first monomer, wherein both the first and second monomer are selected from the group consisting of 3-sulfopropyl acrylate potassium salt, sodium acrylate, N-(tris(hydroxyl methyl)methyl)acrylamide, and 2-acrylamideo-2-methyl-1-propane sulfonic acid. The present disclosure further relates to methods for preparing the copolymer compositions and shaped articles comprising the copolymers.

Abstract: Biocompatible macromer compositions are provided including an isocyanate-functional polyalkylene oxide combined with at least one multi-functional isocyanate as a first component, and a multi-amino functional compound possessing multiple primary amines as a second component. The isocyanate-functional polyalkylene oxide has pendant polyalkylene oxide groups. The resulting biocompatible macromer composition can be employed as an adhesive or sealant for medical/surgical uses.

Abstract: Compositions provided by mixing a biotin-containing component and an avidin-containing component are useful as an adhesive or sealant for medical/surgical uses.

Abstract: Methods for producing biocompatible compositions are provided. The biocompatible compositions include an aliphatic polyester macromer produced without the use of solvents or catalysts. The resulting aliphatic polyester macromer may be reacted with a polyisocyanate to form an end-capped aliphatic polyester macromer which, in turn, may be reacted with a polyol to produce a polyurethane. The polyurethane, in turn, may be reacted with a second polyisocyanate to produce an isocyanate-functional polyurethane. The compositions prepared by the methods of the present disclosure may be used as adhesives or sealants for medical/surgical uses.

Abstract: Novel biodegradable phosphoester polyamines are disclosed. The biodegradable phosphoester polyamines may be utilized as cross-linkers for sprayable compositions which may be used as tissue adhesives or sealants.

Abstract: An apparatus for forming an anastomosis between adjacent intestinal sections of tissue is provided. The apparatus includes a circular surgical stapler having an anvil assembly with an anvil shaft and an anvil, the circular surgical stapler further having a tubular body portion with an annular knife and a body portion shaft selectively attachable to the anvil shaft; and a seal structure for deposition between the intestinal sections of tissue including a hub configured to engage attachment structure on at least one of the anvil shaft and the body portion shaft. The attachment structure is positioned so that the seal structure is located between the intestinal sections of tissue when the circular surgical stapler is disposed within the intestinal sections of tissue.

Abstract: An assembly for joining tissue is provided and includes an anvil assembly and a body portion juxtaposed with respect to one another along a shaft and arranged so as to be approximated with respect to one another; and an applicator supported on the anvil assembly and configured for retaining a wound treatment material therein and for dispensing the wound treatment material therefrom. A method for joining tissue is provided and includes the steps of dispensing the wound treatment material from the applicator so as to distribute wound treatment material onto at least one of a first tissue section and a second tissue section; and approximating the anvil assembly and the body portion to one another so that the first tissue section and the second tissue section are in contact with one another with the dispensed wound treatment material interposed therebetween.

Abstract: Biocompatible macromer compositions are provided including an isocyanate-functional polyalkylene oxide combined with at least one multi-functional isocyanate as a first component, and a multi-amino functional compound possessing multiple primary amines as a second component. The isocyanate-functional polyalkylene oxide has pendant polyalkylene oxide groups. The resulting biocompatible macromer composition can be employed as an adhesive or sealant for medical/surgical uses.

Abstract: Bioabsorbable macromer compositions are provided including a diisocyanate-functional bioabsorbable polymer. In some embodiments, the diisocyanate-functional bioabsorbable polymer can be combined with a functionalized polyol. The resulting bioabsorbable macromer composition can be employed as an adhesive or sealant for medical/surgical uses.

Abstract: Bioabsorbable compositions of A) blends of bioabsorbable homopolymers and/or copolymers containing glycolide and lactide and B) salts of fatty acids and/or fatty acid esters are described. Processes for making the compositions and surgical articles made totally or in part therefrom, including suture coatings, are also described.

Abstract: Flowable bioabsorbable compounds are provided which are useful in producing surgical adhesive or sealant compositions.

Abstract: A kit for storing and applying an adhesive removing device comprising an enclosure which includes a base portion and a removable top layer releasably secured to the base portion; an adhesive removing device including at least one wiping mechanism which includes at least one absorbent portion; and a biocompatible composition including a solvent and a moisturizing agent embedded in the absorbent portion of the wiping mechanism. A method for storing and applying an adhesive removing device comprises a series of steps for using the adhesive removing device to remove an adhesive from a surface.