Abstract: An ultrasonic handpiece includes a piezoelectric element assembly. Control signals drive the piezoelectric element assembly simultaneously in a first mode of oscillation and a second mode of oscillation. Feedback of a resulting oscillation of the piezoelectric element assembly in the first mode and the second mode is generated. Based on the feedback, the frequency of each of the first mode and second mode is independently adjusted, as needed, so that the resulting oscillation of each of the first mode and the second mode is each approximately at its respective resonant frequency.

Abstract: A method of improving cognition in a patient with Down syndrome, which entails intranasally administering one or more ?2-ADR agonists or pharmaceutically-acceptable salts of either or both to the patient in an amount and with a frequency effective to improve cognition of the patient as measured contextual learning tests.

Abstract: A method of improving cognition in a patient with Down syndrome, which entails intranasally administering one or more ?2-ADR agonists or pharmaceutically-acceptable salts of either or both to the patient in an amount and with a frequency effective to improve cognition of the patient as measured contextual learning tests.

Abstract: A method of improving cognition in a patient with Down syndrome, which entails intranasally administering one or more ?2-ADR agonists or pharmaceutically-acceptable salts of either or both to the patient in an amount and with a frequency effective to improve cognition of the patient as measured contextual learning tests.

Abstract: A capsulorhexis apparatus includes a capsulorhexis probe configured for insertion into an eye through an incision and a pulse generator configured to deliver at least one radio-frequency (RF) pulse to the capsulorhexis probe. The delivered RF pulse has a pre-determined attenuation profile such that the power level of the delivered RF pulse is substantially attenuated over the RF pulse's duration. In some embodiments, the pulse generator is configured to deliver a series of two or more RF pulses to the eye, such that the energy of each of the second and subsequent pulses of the series is substantially attenuated relative to the energy of the immediately preceding pulse.

Abstract: A method of improving cognition in a patient with Down syndrome, which entails administering one or more ?2 adrenergic receptor agonists to the patient in an amount and with a frequency effective to improve cognition of the patient as measured by contextual learning tests.

Abstract: A surgical system that is able to sense the onset of an occlusion or other surgical event as well as the instant an occlusion breaks. To help avoid overheating of the tip, the system determines an approximate temperature of the eye using an irrigation flow rate and reduces the power to the handpiece automatically if an overheating situation is predicted. Alternatively or in addition, the system monitors the power drawn by the handpiece, which is indicative of the cutting load on the tip, and automatically adjusts the power to the tip to compensate for increased loads on the tip.

Abstract: A capsulorhexis apparatus includes a capsulorhexis probe configured for insertion into an eye through an incision and a pulse generator configured to deliver at least one radio-frequency (RF) pulse to the capsulorhexis probe. The delivered RF pulse has a pre-determined attenuation profile such that the power level of the delivered RF pulse is substantially attenuated over the RF pulse's duration. In some embodiments, the pulse generator is configured to deliver a series of two or more RF pulses to the eye, such that the energy of each of the second and subsequent pulses of the series is substantially attenuated relative to the energy of the immediately preceding pulse.

Abstract: A capsulorhexis apparatus includes a capsulorhexis probe configured for insertion into an eye through an incision and a pulse generator configured to deliver at least one radio-frequency (RF) pulse to the capsulorhexis probe. The delivered RF pulse has a pre-determined attenuation profile such that the power level of the delivered RF pulse is substantially attenuated over the RF pulse's duration. In some embodiments, the pulse generator is configured to deliver a series of two or more RF pulses to the eye, such that the energy of each of the second and subsequent pulses of the series is substantially attenuated relative to the energy of the immediately preceding pulse.

Abstract: A method of treating an individual having Down syndrome or Alzheimer's disease, which entails the step of administering an amount of one or more compounds to the individual which improve cognitive functioning in the individual by increasing hippocampal NE levels.

Abstract: A motion-sensing input device for control of a microsurgical system is disclosed, comprising a housing including a plurality of walls defining a cavity, a plurality of motion-sensing screens, and a processor. Each motion sensing screen of the plurality of motion-sensing screens is mounted within the cavity of the housing, and each motion-sensing screen is configured to detect positional data of an object within the cavity relative to the housing. The processor is operable to analyze the positional data and transmit corresponding command signals to the microsurgical system.

Abstract: A handpiece having at least one set of piezoelectric elements polarized to produce longitudinal motion when excited at the relevant resonant frequency. The piezoelectric crystals are connected to an ultrasonic horn to which a cutting tip is attached. The horn and/or the cutting tip contains a plurality of diagonal slits or grooves. The slits or grooves produce optimized torsional movement in the cutting tip when the piezoelectric crystals are excited at a second resonant frequency.

Abstract: A method of improving cognition in a patient with Down syndrome, which entails administering one or more ?2 adrenergic receptor agonists to the patient in an amount and with a frequency effective to improve cognition of the patient as measured by contextual learning tests

Abstract: The present invention comprises a method of operating an ophthalmic surgical hand piece, providing a series of power pulses to the hand piece, each of the series of power pulses having a first portion that produces torsional movement of a cutting tip and a second portion that produces longitudinal movement of the cutting tip; measuring vacuum pressure; altering the duration of the first portion as vacuum pressure increases; and altering the duration of the second portion as vacuum pressure increases.

Abstract: A surgical system that is able to sense the onset of an occlusion or other surgical event as well as the instant an occlusion breaks. To help avoid overheating of the tip, the system determines an approximate temperature of the eye using an irrigation flow rate and reduces the power to the handpiece automatically if an overheating situation is predicted. Alternatively or in addition, the system monitors the power drawn by the handpiece, which is indicative of the cutting load on the tip, and automatically adjusts the power to the tip to compensate for increased loads on the tip.

Abstract: The present invention comprises a method of operating an ophthalmic surgical hand piece, providing a series of power pulses to the hand piece, each of the series of power pulses having a first portion that produces torsional movement of a cutting tip and a second portion that produces longitudinal movement of the cutting tip; measuring vacuum pressure; altering the duration of the first portion as vacuum pressure increases; and altering the duration of the second portion as vacuum pressure increases.

Abstract: Phacoemulsification systems and associated user interfaces and methods for use in ophthalmic surgery are disclosed. In some embodiments, a touch screen display of an ophthalmic surgical console provides a graphical user interface that allows a user to both visualize and control various operating parameters of the surgical console and associated subsystems. The controllable operating parameters include, without limitation, aspiration flow rates, IV pole height, vacuum limit pressures, minimum ultrasound power, maximum ultrasound power, on-time, off-time, and/or other values associated with the operating parameters of the ophthalmic surgical console.

Abstract: A control system for managing power supplied to a phacoemulsification hand piece includes a power source that provides power to the hand piece and a controller that controls the power source. The controller calculates a thermal value based on irrigation fluid flow and a power level and decreases the power level in proportion to the calculated thermal value when the calculated thermal value exceeds a threshold thermal value. Irrigation fluid flow can be calculated from irrigation fluid pressure.

Abstract: A surgical system that is able to sense the onset of an occlusion or other surgical event as well as the instant an occlusion breaks. To help avoid overheating of the tip, the system determines a temperature of an eye using irrigation flow rate and reduces the power to the handpiece automatically if an overheating situation is predicted. Alternatively or in addition, the system monitors the power drawn by the handpiece, which is indicative of the cutting load on the tip, and automatically adjusts the power or stroke of the tip to compensate for increased loads on the tip.

Abstract: Embodiments of systems and methods for an interface for providing a user with feedback are presented. Specifically, embodiments of such an interface may include a head-up display unit which is mounted on a microscope utilized by a user when performing a surgical procedure. The heads-up display unit may include an eye-piece ring which is fitted onto or in one of the eye pieces of the microscope. The heads-up unit receives data regarding one or more parameters from a surgical console or other source and produces audio or visual feedback corresponding to a desired parameter. Any visual feedback produced may then be propagated to the eye piece ring allowing a user of the microscope to obtain the feedback when performing a surgical procedure utilizing the microscope and obviating the need to look at a screen of the surgical console to obtain such feedback. Thus, feedback is provided to a user in a non-intrusive manner such that the user can obtain this feedback without distracting from a surgical procedure.