Patents by Inventor Ahmed A. Eltoukhy

Ahmed A. Eltoukhy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,3,5-triazinane-2,4,6-trione derivatives and uses thereof
    Patent number: 9315472
    Abstract: The present invention provides novel 1,3,5-triazinane-2,4,6-trione derivatives, such as compounds of any one of Formulae (I) and (II), and salts thereof, and methods of preparing the compounds. Also provided are compositions including a compound of the invention and an agent (e.g., an siRNA, mRNA, or plasmid DNA). The present invention also provides methods and kits using the compositions for delivering an agent to a subject (e.g., to the liver, spleen, or lung of the subject) or cell and for treating and/or preventing a range of diseases, such as genetic diseases, proliferative diseases, hematological diseases, neurological diseases, liver diseases, and lung diseases.
    Type: Grant
    Filed: May 1, 2014
    Date of Patent: April 19, 2016
    Assignee: Massachusetts Institute of Technology
    Inventors: Yizhou Dong, Akinleye C. Alabi, Hao Yin, Joseph R. Dorkin, Delai Chen, Robert S. Langer, Daniel Griffith Anderson, Ahmed A. Eltoukhy
  • 1,3,5-TRIAZINANE-2,4,6-TRIONE DERIVATIVES AND USES THEREOF
    Publication number: 20140329884
    Abstract: The present invention provides novel 1,3,5-triazinane-2,4,6-trione derivatives, such as compounds of any one of Formulae (I) and (II), and salts thereof, and methods of preparing the compounds. Also provided are compositions including a compound of the invention and an agent (e.g., an siRNA, mRNA, or plasmid DNA). The present invention also provides methods and kits using the compositions for delivering an agent to a subject (e.g., to the liver, spleen, or lung of the subject) or cell and for treating and/or preventing a range of diseases, such as genetic diseases, proliferative diseases, hematological diseases, neurological diseases, liver diseases, and lung diseases.
    Type: Application
    Filed: May 1, 2014
    Publication date: November 6, 2014
    Inventors: Yizhou Dong, Akinleye C. Alabi, Hao Yin, Joseph R. Dorkin, Delai Chen, Robert S. Langer, Daniel Griffith Anderson, Ahmed A. Eltoukhy