Abstract: There is described a method of performing intra-lesional cryosurgery utilizing a specifically shaped tubular needle having a front piercing surface coextensive with an opening. The needle is introduced into the skin from one point and runs through deeper tissues based on the surface orientation of the needle. The piercing surface of the needle is directed through a second point where it emerges from the skin. The needle as indicated is a hollow tubular member and has one end which is adapted to receive a source of a cryrogen gas. The gas is passed through the needle and produces a lowering of the needle temperature. This low temperature is directed to the surrounding tissues to form an ice cylinder about the imbedded part of the needle in the deeper tissues. This ice cylinder affords to selectively freeze the tissue and thereby destroys the lesion being treated. A plurality of different shaped needles are shown to accommodate different types and different depth lesions.