Abstract: A laser catheter having a compliant balloon and a plurality of optical fibers extending from a base to a tip of the catheter for plaque removal is disclosed. The laser catheter may include a distal flush lumen extending to the tip. The compliant balloon may extend along a longitudinal axis of the laser catheter and may be positioned radially outward from an inner lumen. A plurality of optical fibers may be positioned between the inner lumen and an outer compliant material jacket. In another embodiment, the compliant balloon may be positioned eccentrically with respect to the inner lumen. The eccentrically positioned compliant balloon may further facilitate removal of plaque within arteries.