Patents by Inventor Ahmed M. Naglah

Ahmed M. Naglah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pentacyclic triterpenoidal derivatives
    Patent number: 9975917
    Abstract: A pentacyclic triterpenoidal derivative can include 3,11-dioxo-24(phenyl)-urs-12-en-24-one (4), 24-norurs-12-en-24(phenyl)-3,11-dione (5), 3,11-dioxo-24(Phenyl)-urs-1,12-diene-24-one (6), or 24-nor-urs-1,12-diene-24(phenyl)-3,11-dione (7). The pentacyclic triterpenoidal derivative demonstrates highly potent 5-lipoxygenase inhibition activity.
    Type: Grant
    Filed: September 20, 2017
    Date of Patent: May 22, 2018
    Assignee: KING SAUD UNIVERSITY
    Inventors: Abd El-Galil E. Amr, Mohamed A. Al-Omar, Ahmed M. Naglah
  • Oleanolic acid methyl ester derivatives
    Patent number: 9969768
    Abstract: Oleanolic acid methyl ester derivatives demonstrate potent anti-diabetic activities. In in vitro anti-diabetic testing, the derivatives showed more potency regarding dipeptidyl peptidase-4 (DPP-IV) inhibitor activity, peroxisome proliferator-activated receptors (PPARs) agonist activity, and ?-Glucosidase inhibitors activity, as compared to reference standards oleanolic acid and acarbose. In in vivo oral hypoglycemic testing, both acute and sub-acute studies demonstrated that the derivatives had high potency and long duration of action compared to the reference standards pioglitazone, acarbose and oleanolic acid.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: May 15, 2018
    Assignee: KING SAUD UNIVERSITY
    Inventors: Ahmed M. Naglah, Abd El-Galil E. Amr, Mohamed A. Al-Omar