Abstract: A method of preparing nanoparticles of carbon-supported copper manganite (CuMn2O4) comprising: preparing a first solution of a copper (II) salt and a manganese salt in a first polar organic solvent, where the molar ratio of Cu:Mn is from about 0.8:1 to about 1.2:1; admixing a second solution containing an organic ligand in a second polar organic solvent with the first solution to form a first mixture, wherein the second polar organic solvent is miscible with the first polar organic solvent; hydrothermally heating the obtained mixture at a temperature of from about 100° C. to about 200° C. for a duration sufficient to yield a solid metal-organic framework composite material; and, calcining the composite material at a temperature in the range of from about 350° C. to about 600° C.

Abstract: A method for remediating fractures in a cement structure including heating the cement structure to a temperature at or above the melting temperature of the eutectic metal alloy particles to allow the particles to flow in liquid state into the fractures in the cement structure until the heat source is discontinued, allowing the particles to cool and solidify.

Abstract: A fluid composition including a mixed metal oxide viscosifier, a clay viscosifier, and solid eutectic metal alloy particles. A method including pumping a drilling fluid downhole in a wellbore. The drilling fluid including water, a mixed metal oxide viscosifier, a clay viscosifier, and solid eutectic metal alloy particles. The method further including allowing the drilling fluid to reach a target zone with elevated permeability and forming a filter cake containing solid eutectic metal alloy particles in the target zone. The method including heating the filter cake to a temperature greater than the melting temperature of the eutectic metal alloy particles, allowing the particles to melt and become liquid eutectic metal alloy particles. The method including discontinuing heating and allowing the filter cake to cool to a temperature lower than the melting temperature of the solid eutectic metal alloy particles to produce a strengthened filter cake.

Abstract: The present invention relates to a functionally active mutated primase domain from an archaeal DNA primase belonging to the primase-polymerase family, comprising at least one amino acid substitution, wherein said mutated primase domain retains at least 50% of the template-independent terminal nucleotidyl transferase activity of the corresponding wild-type primase domain.

Abstract: The present invention relates to variant of Family A polymerases able to synthesize a nucleic acid fragment without template and to incorporate a reversible modified terminator nucleotide during the nucleic acid fragment synthesis. The present invention further relates to uses thereof for enzymatic synthesis of nucleic acid molecules.

Abstract: A eutectic metal alloy is placed through a coiled tubing into a wellbore formed in a subterranean formation. The eutectic metal alloy includes a mixture of multiple metals. The eutectic metal alloy has a melting temperature that is less than a melting temperature of each individual metal of the multiple metals making up the eutectic metal alloy. The eutectic metal alloy is heated to a temperature equal to or greater than the melting temperature of the eutectic metal alloy to liquefy the eutectic metal alloy. The liquefied eutectic metal alloy is flowed from the wellbore and into the subterranean formation, thereby exposing the liquefied eutectic metal alloy to a specified downhole temperature within the subterranean formation and causing the liquefied eutectic metal alloy to solidify to form a seal. The seal prevents fluid from flowing from the wellbore and into the subterranean formation.

Abstract: The present invention relates to a reaction unit (10) configured to receive a reaction solution or culture media and configured to be placed inside a thermocycler, said reaction unit (10) comprising an elongated hollow body (12) extending along a flowing axis X, the hollow body (12) thus displaying a first opening (14) at its first extremity (16) and a second opening (18) at its second extremity (20). The walls of the hollow body (12) are at least partially made of a thermally conductive material. The reaction unit (10) further comprises at least one filter element (22) extending inside the hollow body (12), the filter element (22) being sealingly secured to the walls of the hollow body (12) over its complete circumference, leading any fluid flowing from the first opening (14) to the second opening (18) to cross the at least one filter element (22).

Abstract: Thermocycling multistep reaction device comprising a reaction plate (12) comprising at least one well (14) and at least one internal fluid circulation channel arranged around the at least one well (14), an evacuation system (16), a first circuit being aimed, when activated, at driving a first heat transfer fluid through the at least one internal fluid circulation channel, a second circuit being aimed, when activated, at driving a second heat transfer fluid through the at least one internal fluid circulation channel, and a control unit. The temperature inside the at least one well (14) is regulated and controlled by means of the control unit which selectively activates the circuits, each well (14) is connected to the evacuation system (16) by means of at least one filter membrane.

Abstract: Thermocycling multistep reactions device (10) comprising: a reaction plate (12) comprising at least one well (14), at least one internal thermoregulating fluid circulation circuit configured to be arranged in direct contact with the at least one well (14), an evacuation system, a control unit configured to manage the temperature of the internal thermoregulating fluid circuit. The temperature inside the at least one well (14) is regulated and controlled by means of the control unit. Each well (14) is connected to the evacuation system by means of at least one filter membrane, and the thermoregulating fluid circuit is made of a heat conducting material while the reaction plate is made (12) of a polymerous material.

Abstract: Compositions for treating a wellbore include an exothermic additive capable of initiating an exothermic event following contact with a carrier fluid. The exothermic additive can have a coating that delays the exothermic event after contact with the carrier fluid. Methods disclosed herein include emplacing a fluid loss treatment composition in an interval of a wellbore, the fluid loss treatment including: a metallic fluid loss additive; an exothermic additive; and a carrier fluid; and reacting the exothermic additive to initiate an increase in temperature in the interval of the wellbore above a melting point of the metallic fluid loss additive; and converting the metallic fluid loss additive to a molten fluid loss additive; and treating the interval of the wellbore with the molten fluid loss additive.

Abstract: An underpinning device for support a structure is provided. The underpinning device is anchored within the ground using a grout or cement. The underpinning device comprises a rod having a proximal rod end and a distal rod end. A first interacting element is coupled to the proximal rod end and is encased in the slab of a building. A second interacting element is coupled to the distal rod end and include a removable tip. Upon insertion into the ground, the tip dissociates from the second interacting element creating an opening at the distal rod end. A fluid, such as grout and/or cement is injected into the pipe and extruded through channels within the rod. The fluid is then allowed to cure thereby anchoring the underpinning device within the ground.

Abstract: The invention relates to the field of nucleic acid synthesis or sequencing, more specifically to methods for ab-initio synthesis of nucleic acids, comprising contacting a nucleotide with a free 3?-hydroxyl group, with at least one nucleoside triphosphate, or a combination of nucleoside triphosphates, in the presence of an archaeal DNA primase or a functionally active fragment and/or variant thereof, thereby covalently binding said nucleoside triphosphate to the free 3?-hydroxyl group of the nucleotide. It also relates to isolated functionally active fragments of archaeal DNA primases which are capable of both ab-initio single-stranded nucleic acid synthesis activity and template-independent terminal nucleotidyl transferase activity.

Abstract: The invention relates to methods for template-independent synthesis of nucleic acids, comprising iteratively contacting an initiator sequence comprising a 3?-end nucleotide with a free 3?-hydroxyl group, with at least one nucleoside triphosphate, or a combination of nucleoside triphosphates, in the presence of an archaeal DNA primase or a functionally active fragment and/or variant thereof, thereby covalently binding said nucleoside triphosphate to the free 3-hydroxyl group of the 3-end nucleotide. It also relates to isolated functionally active fragments of archaeal DNA primases which are capable of template-independent terminal nucleotidyl transferase activity but are devoid of a template-independent primase activity.

Abstract: A cannabinoid-HA conjugate, according to the present invention, has a polysaccharide backbone of hyaluronic acid or an analog or derivative thereof, having a cannabinoid attached by way of a spacer to one or more derivatization sites of the polysaccharide backbone selected from the group consisting of: a primary hydroxyl group, a secondary hydroxyl group, a carboxyl group, and an acetamido group. One or more of the cannabinoids may be used as a cross-linking agent to covalently cross-link the polysaccharide backbone to control biodegradation and duration of action.

Abstract: The present invention relates to variant of Family A polymerases able to synthesize a nucleic acid fragment without template and to incorporate a reversible modified terminator nucleotide during the nucleic acid fragment synthesis. The present invention further relates to uses thereof for enzymatic synthesis of nucleic acid molecules.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for agent trajectory prediction using context-sensitive fusion.

Abstract: The present invention relates to variant of Family A polymerases able to synthesize a nucleic acid fragment without template and to incorporate a reversible modified terminator nucleotide during the nucleic acid fragment synthesis. The present invention further relates to uses thereof for enzymatic synthesis of nucleic acid molecules.

Abstract: The present invention relates to variant of Family A polymerases able to synthesize a nucleic acid fragment without template and to incorporate a reversible modified terminator nucleotide during the nucleic acid fragment synthesis. The present invention further relates to uses thereof for enzymatic synthesis of nucleic acid molecules.

Abstract: A method for proactively detecting shared libraries suspected of association with malware includes the steps of determining one or more shared libraries loaded on an electronic device, determining that one or more of the shared libraries include suspicious shared libraries by determining that the shared library is associated with indications that the shared library may have been maliciously injected, loaded, and/or operating on the electronic device, and identifying the suspicious shared libraries to a reputation server.

Abstract: A system, method and computer program product are provided for sending, to a central system, information associated with unwanted activity. In use, information associated with unwanted activity is identified utilizing a plurality of different types of security systems. Further, the information is sent to a central system.