Patents by Inventor Ahmed Sayed Ibrahim Aly

Ahmed Sayed Ibrahim Aly has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VIRAL-VECTORED VACCINE FOR MALARIA
    Publication number: 20210324416
    Abstract: A malaria vaccine composition is disclosed herein that uses liver-stage parasite exported proteins as the target of a protective immune response instead of sporozoite proteins. Also disclosed is a recombinant viral particle that comprises a fusion protein disclosed herein, wherein the malaria antigen is displayed within the viral particle. Also disclosed is an isolated polynucleotide that comprises a nucleic acid sequence encoding a fusion protein disclosed herein operably linked to an expression control sequence. Also disclosed is a recombinant herpes simplex virus (HSV) genome comprising a modified VP26 gene encoding a fusion protein disclosed herein. Also disclosed is a vaccine composition that comprises a recombinant viral particle disclosed herein in a pharmaceutically acceptable excipient. In some cases, the composition further comprises an adjuvant.
    Type: Application
    Filed: June 28, 2019
    Publication date: October 21, 2021
    Inventors: Konstantin Kousoulas, Paul Rider, Ahmed Sayed Ibrahim Aly
  • Live genetically attenuated malaria vaccine
    Patent number: 8168166
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
    Type: Grant
    Filed: May 6, 2008
    Date of Patent: May 1, 2012
    Assignees: Seattle Biomedical Research Institute, Walter and Eliza Hall Institute of Medical Research
    Inventors: Stefan H. I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller, Kelley van Buskirk, Mehdi Labaied, Ahmed Sayed Ibrahim Aly, Alan Frederick Cowman, Alexander Gerd Maier
  • LIVE GENETICALLY ATTENUATED MALARIA VACCINE
    Publication number: 20110033502
    Abstract: Method for inoculating a vertebrate host against malaria, by administering to the host a live Plasmodium organism that is genetically engineered to disrupt a liver-stage-specific gene function.
    Type: Application
    Filed: May 6, 2008
    Publication date: February 10, 2011
    Inventors: Stefan H.I. Kappe, Kai-Uwe C. Matuschewski, Ann-Kristin Mueller, Kelley van Buskirk, Mehdi Labaied, Ahmed Sayed Ibrahim Aly, Alan Frederick Cowman, Alexander Gerd Maier