Patents by Inventor Ahsan Husain

Ahsan Husain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inducing Proliferation of Cardiomyocytes and Therapeutic Uses Related Thereto
    Publication number: 20210299078
    Abstract: This disclosure relates to methods of treating or preventing heart malformations or cardiovascular diseases comprising administering an effective amount of thyroid hormone in combination with i) an agent that decreases DUSPS and/or DUSP6 expression and/or ii) a beta-adrenergic blocking agent to a subject in need thereof. In certain embodiments, this disclosure relates to in vivo and in vitro methods of inducing proliferation of cardiomyocytes using agents or combinations of agents disclosed herein.
    Type: Application
    Filed: August 14, 2019
    Publication date: September 30, 2021
    Inventors: Nawazish Naqvi, Ahsan Husain
  • Chymase compositions, antibodies, diagnostics, and therapeutic methods related thereto
    Patent number: 9724412
    Abstract: The disclosure relates to chymase, antibodies to chymase, and diagnostic and therapeutic methods relates thereto. It has been discovered that above certain circulating levels of chymase, a patient has a high likelihood of arteriovenous fistula nonmaturation. Compositions and methods of detecting and measuring chymase levels are disclosure herein. In certain embodiments, the disclosure relates to methods of determining the effectiveness of creating an arteriovenous fistula in a subject diagnosed with chronic kidney disease.
    Type: Grant
    Filed: July 11, 2012
    Date of Patent: August 8, 2017
    Assignee: Emory University
    Inventors: Haimanot Wasse, Ahsan Husain, Nawazish Ali Naqvi
  • CHYMASE COMPOSITIONS, ANTIBODIES, DIAGNOSTICS, AND THERAPEUTIC METHODS RELATED THERETO
    Publication number: 20140220024
    Abstract: The disclosure relates to chymase, antibodies to chymase, and diagnostic and therapeutic methods relates thereto. It has been discovered that above certain circulating levels of chymase, a patient has a high likelihood of AVF nonmaturation. Compositions and methods of detecting and measuring chymase levels are disclosure herein. In certain embodiments, the disclosure relates to methods of determining the effectiveness of creating an arteriovenous fistula in a subject diagnosed with chronic kidney disease.
    Type: Application
    Filed: July 11, 2012
    Publication date: August 7, 2014
    Applicant: EMORY UNIVERSITY
    Inventors: Haimanot Wasse, Ahsan Husain, Nawazish Ali Naqvi
  • MODULATORS OF CARDIAC CELL HYPERTROPHY AND HYPERPLASIA
    Publication number: 20090304625
    Abstract: Provided are compositions and methods for modulating cardiac cell hypertrophy and hyperplasia using inhibitors of c-Kit activity.
    Type: Application
    Filed: January 18, 2007
    Publication date: December 10, 2009
    Inventors: Ahsan Husain, Nawazish Naqvi, Robert M. Graham, Louis J. Dell'talia, Ming Li
  • Tryptase polypeptide and uses thereof
    Patent number: 7521533
    Abstract: The present invention provides a purified expressed ? tryptase polypeptide or fragment or analogue thereof, in particular, the human ? tryptase polypeptide or fragment or analogue thereof. The present invention also provides variants of such polypeptides. The invention further relates to methods of diagnosing disease states based on expression of these polypeptides and methods of screening for compounds that interact, bind and/or modulate the activity of the polypeptides.
    Type: Grant
    Filed: February 28, 2003
    Date of Patent: April 21, 2009
    Inventors: John E. Hunt, Hong-Wei Wang, Hugh Patrick McNeil, Ahsan Husain
  • Tryptase polypeptide and uses thereof
    Publication number: 20060177875
    Abstract: The present invention provides a purified expressed ? tryptase polypeptide or fragment or analogue thereof, in particular, the human ? tryptase polypeptide or fragment or analogue thereof. The present invention also provides variants of such polypeptides. The invention further relates to methods of diagnosing disease states based on expression of these polypeptides and methods of screening for compounds that interact, bind and/or modulate the activity of the polypeptides.
    Type: Application
    Filed: February 28, 2003
    Publication date: August 10, 2006
    Inventors: John Hunt, Hong-Wei Wang, Hugh McNeil, Ahsan Husain