Patents by Inventor Ai Ling Ching

Ai Ling Ching has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Formulation of a pan-JAK inhibitor
    Patent number: 11795180
    Abstract: The present disclosure relates to pharmaceutical compositions comprising (3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile), methods of use thereof, and methods of preparation.
    Type: Grant
    Filed: October 7, 2021
    Date of Patent: October 24, 2023
    Assignee: THERAVANCE BIOPHARMA R&D IP, LLC
    Inventors: Bernardus Joseph Nitert, Yvonne Rosiaux, Marian E. Van Der Veen, Nathan Schulpen, Jens Maes, Guido Verniest, Venkat R. Thalladi, Ai Ling Ching
  • Lisinopril compositions with an ingestible event marker
    Patent number: 11684605
    Abstract: Provided herein are compositions for the ingestible administration of lisinopril. In some embodiments the compositions comprise lisinopril and silicon. In some embodiments, the compositions comprise lisinopril, silicon, magnesium metal, and copper (I) chloride. Also provided herein are apparatuses comprising the compositions provided herein. Also provided herein are methods for using the compositions and apparatuses provided herein.
    Type: Grant
    Filed: October 6, 2021
    Date of Patent: June 27, 2023
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Kurt Scheinpflug, Nikhil Pargaonkar, Chris Dong, Ai Ling Ching, Dawn Adkin
  • Administration of gut-selective JAK3 inhibitor
    Patent number: 11471442
    Abstract: Methods of safely administrating a gut-selective JAK3 inhibitor by oral administration are described. Also described are methods for providing clinically proven safe treatment of gastrointestinal inflammatory diseases, such as celiac disease, by oral administration of a gut-selective JAK3 inhibitor.
    Type: Grant
    Filed: May 10, 2021
    Date of Patent: October 18, 2022
    Assignee: Theravance Biopharma R&D IP, LLC
    Inventors: Marie T. Borin, David L. Bourdet, Ai Ling Ching, Arthur Lo
  • FORMULATION OF A PAN-JAK INHIBITOR
    Publication number: 20220112220
    Abstract: The present disclosure relates to pharmaceutical compositions comprising (3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile), methods of use thereof, and methods of preparation.
    Type: Application
    Filed: October 7, 2021
    Publication date: April 14, 2022
    Inventors: Bernardus Joseph Nitert, Yvonne Rosiaux, Marian E. Van Der Veen, Nathan Schulpen, Jens Maes, Guido Verniest, Venkat R. Thalladi, Ai Ling Ching
  • LISINOPRIL COMPOSITIONS WITH AN INGESTIBLE EVENT MARKER
    Publication number: 20220079919
    Abstract: Provided herein are compositions for the ingestible administration of lisinopril. In some embodiments the compositions comprise lisinopril and silicon. In some embodiments, the compositions comprise lisinopril, silicon, magnesium metal, and copper (I) chloride. Also provided herein are apparatuses comprising the compositions provided herein. Also provided herein are methods for using the compositions and apparatuses provided herein.
    Type: Application
    Filed: October 6, 2021
    Publication date: March 17, 2022
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Kurt Scheinpflug, Nikhil Pargaonkar, Chris Dong, Ai Ling Ching, Dawn Adkin
  • ADMINISTRATION OF GUT-SELECTIVE JAK3 INHIBITOR
    Publication number: 20210353597
    Abstract: Methods of safely administrating a gut-selective JAK3 inhibitor by oral administration are described. Also described are methods for providing clinically proven safe treatment of gastrointestinal inflammatory diseases, such as celiac disease, by oral administration of a gut-selective JAK3 inhibitor.
    Type: Application
    Filed: May 10, 2021
    Publication date: November 18, 2021
    Inventors: Marie T. BORIN, David L. BOURDET, Ai Ling CHING, Arthur LO
  • Lisinopril compositions with an ingestible event marker
    Patent number: 11166939
    Abstract: Provided herein are compositions for the ingestible administration of lisinopril. In some embodiments the compositions comprise lisinopril and silicon. In some embodiments, the compositions comprise lisinopril, silicon, magnesium metal, and copper (I) chloride. Also provided herein are apparatuses comprising the compositions provided herein. Also provided herein are methods for using the compositions and apparatuses provided herein.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: November 9, 2021
    Assignee: OTSUKA PHARMACEUTICAL CO. LTD
    Inventors: Kurt Scheinpflug, Nikhil Pargaonkar, Chris Dong, Ai Ling Ching, Dawn Adkin
  • Alginate on adhesive bilayer laminate film
    Patent number: 11051543
    Abstract: An ingestible compositions includes a first polymer layer, an adhesive layer associated with the first polymer layer, where the adhesive layer includes an adhesive material and is configured to releasably adhere to the first polymer layer, an alginate layer adhered to the adhesive layer, and a second polymer layer associated with the alginate layer and configured to releasably adhere to the alginate layer. Aspects further include methods of making and using the compositions.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: July 6, 2021
    Assignee: OTSUKA PHARMACEUTICAL CO. LTD.
    Inventors: Raymond Schmidt, Hooman Hafezi, Ai Ling Ching, Patricia Johnson, Anuj Patel, Kevin Cheng, Kosuke Iwai
  • LISINOPRIL COMPOSITIONS WITH AN INGESTIBLE EVENT MARKER
    Publication number: 20190216776
    Abstract: Provided herein are compositions for the ingestible administration of lisinopril. In some embodiments the compositions comprise lisinopril and silicon. In some embodiments, the compositions comprise lisinopril, silicon, magnesium metal, and copper (I) chloride. Also provided herein are apparatuses comprising the compositions provided herein. Also provided herein are methods for using the compositions and apparatuses provided herein.
    Type: Application
    Filed: April 25, 2018
    Publication date: July 18, 2019
    Inventors: Kurt Scheinpflug, Nikhil Pargaonkar, Chris Dong, Ai Ling Ching, Dawn Adkin
  • ALGINATE ON ADHESIVE BILAYER LAMINATE FILM
    Publication number: 20170020182
    Abstract: An ingestible compositions includes a first polymer layer, an adhesive layer associated with the first polymer layer, where the adhesive layer includes an adhesive material and is configured to releasably adhere to the first polymer layer, an alginate layer adhered to the adhesive layer, and a second polymer layer associated with the alginate layer and configured to releasably adhere to the alginate layer. Aspects further include methods of making and using the compositions.
    Type: Application
    Filed: July 21, 2016
    Publication date: January 26, 2017
    Inventors: Raymond Schmidt, Hooman Hafezi, Ai Ling Ching, Patricia Johnson, Anuj Patel, Kevin Cheng, Kosuke Iwai
  • COMPOSITIONS COMPRISING A SHELF-LIFE STABILITY COMPONENT
    Publication number: 20130129869
    Abstract: Compositions that include a shelf-life stability component are provided. In some instances, the compositions are ingestible compositions which include the shelf-life stability component and an ingestible component. Aspects of the invention further include methods of making and using the compositions.
    Type: Application
    Filed: November 23, 2011
    Publication date: May 23, 2013
    Inventors: Hooman Hafezi, Raymond Schmidt, Ai Ling Ching