Abstract: This invention provides a substance that exhibits excellent life-lengthening effects on cells, that is excellent in terms of productivity, and that has low immunological toxicity. The present invention relates to a preservative for a biomaterial comprising (a) a peptide consisting of the amino acid sequence as shown in SEQ ID NO: 6 or (b) a peptide consisting of an amino acid sequence derived from the amino acid sequence as shown in SEQ ID NO: 6 by deletion, substitution, insertion, or addition of 1 or several amino acids and having life-lengthening effects on cells and a method for preserving a biomaterial utilizing such peptide.

Abstract: An antifreeze protein is added to a hydrous material when the hydrous material contains water molecules and a substance other than water molecules, and freeze concentration of the substance should be inhibited; when the hydrous material contains a bioactive substance and inactivation of the bioactive substance should be inhibited; or when the hydrous material contains water molecules and a component other than the water molecules, and a frozen product or freeze-dried product in which the component is homogeneously dispersed should be produced.

Abstract: The present invention is intended to promote the utilization of antifreeze proteins by obtaining antifreeze proteins from fish species inhabiting water areas in Japan, water areas close to Japan, or water areas wherein the climate is equivalent to that of the above water areas, and particularly from fish species selected from the genera Myoxocephalus, Gymnocanthus, Hemilepidotus, Furcina, Hypomesus, Spirinchus, Mallotus, Pleurogrammus, Sebastes, Clupea, Limanda, Liopsetta, Clidoderma, Cleisthenes, Microstomus, Lepidopsetta, Platichthys, Kareius, Eopsetta, Gadus, Theragra, Ammodytes, Hypoptychus, Trachurus, Brachyopsis, Pholis, Opisthocentrus, Zoarces, Ascoldia, Pholidapus and Etrumeus.