Patents by Inventor Aidaris Jimenez

Aidaris Jimenez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cold sterilization of tissue engineering scaffolds with compressed carbon dioxide
    Patent number: 8721963
    Abstract: Methods for sterilizing a biocompatible hydrogel polymer are provided via treating the biocompatible hydrogel polymer with a supercritical CO2 treatment composition at a treatment pressure of about 4 MPa to about 30 MPa and a treatment temperature of about 5° C. to about 75° C. The supercritical CO2 treatment composition can be substantially pure CO2 or may further include hydrogen peroxide (e.g., in an amount of about 10 ppm to about 1,000 ppm). In certain embodiments, the biocompatible hydrogel polymer can be treated with the supercritical CO2 treatment composition for about 30 minutes to about 5 hours. According to these methods, treating the biocompatible hydrogel polymer can kill about 90% or more of any S. aureus and E. coli present in the biocompatible hydrogel polymer.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: May 13, 2014
    Assignee: University of South Carolina
    Inventors: Michael A. Matthews, Jian Zhang, Aidaris Jimenez
  • Cold Sterilization of Tissue Engineering Scaffolds with Compressed Carbon Dioxide
    Publication number: 20110236256
    Abstract: Methods for sterilizing a biocompatible hydrogel polymer are provided via treating the biocompatible hydrogel polymer with a supercritical CO2 treatment composition at a treatment pressure of about 4 MPa to about 30 MPa and a treatment temperature of about 5° C. to about 75° C. The supercritical CO2 treatment composition can be substantially pure CO2 or may further include hydrogen peroxide (e.g., in an amount of about 10 ppm to about 1,000 ppm). In certain embodiments, the biocompatible hydrogel polymer can be treated with the supercritical CO2 treatment composition for about 30 minutes to about 5 hours. According to these methods, treating the biocompatible hydrogel polymer can kill about 90% or more of any S. aureus and E. coli present in the biocompatible hydrogel polymer.
    Type: Application
    Filed: March 29, 2011
    Publication date: September 29, 2011
    Applicant: UNIVERSITY OF SOUTH CAROLINA
    Inventors: Michael A. Matthews, Jian Zhang, Aidaris Jimenez