Abstract: A medical device may comprise a distal tip having a viewing element, a lighting element, and at least one feature configured to removably couple the distal tip to a shaft. The medical device may also comprise a working channel coupled to the distal tip and defining a central lumen configured to receive a tool. A wall of the working channel may define at least one additional lumen. The working channel may be configured to be removably inserted into the shaft. The medical device may also comprise at least one of a wire, a cable, or a conduit passing through the at least one additional lumen.

Abstract: An implant system and method of delivery includes a catheter system including a sling catheter having a plurality of distal openings and a delivery catheter, disposed within the sling catheter and having a distal port. Suture coupled anchors may be sequentially delivered by the delivery catheter to a cardiac treatment site by aligning the port of the delivery catheter with different openings of the sling catheter and pushing the anchor through the port and the sling catheter to embed the anchor into cardiac tissue such as tissue of a papillary muscle. Each anchor may have a linear configuration for translation within the delivery catheter and a biased configuration that inhibits its reentry into the sling catheter once deployed. Once all anchors are deployed, the suture may be tightened, the anchored portion of the sling catheter may be detached, and the catheter system withdrawn.

Abstract: A medical device may include a main shaft extending from a proximal end to a distal end; an actuator at a proximal portion of the medical device; an end effector positioned at a distal end of the main shaft and comprising a first jaw and a second jaw; a motor; and a torque amplification system. The torque amplification system may include a driveshaft coupled to the motor; a spring coupled to the driveshaft and configured to expand or contract in a proximal or a distal direction relative to the driveshaft; a hammer moveably coupled to the driveshaft; and an anvil coupled to the end effector and abutting the hammer. The anvil may be configured to provide a rotational power output to the end effector to move the first jaw and/or the second jaw.

Abstract: An implantable device for encapsulating cells includes one or more cell encapsulation layers. Each of the cell encapsulation layers includes a first membrane that is semipermeable, a second membrane that is semipermeable, and a first plurality of weld lines. The second membrane is attached to the first membrane by the first plurality of weld lines. The first membrane, the second membrane, and the first plurality of weld lines define at least one cell channel for encapsulating cells. The cell encapsulation device is configurable between a collapsed configuration and an inflated configuration.

Abstract: A motorized control system for a medical device may include a control assembly including a first body with a cradle assembly and a second body moveably coupled to the first body. The cradle assembly may be configured to removably couple to the medical device. The second body may include a gear assembly, a first motor configured to drive a first gear of the gear assembly, and a second motor configured to drive a second gear of the gear assembly. The control assembly may be configured to transition between an open configuration and a closed configuration. The gear assembly may be configured to receive a plurality of knobs of the medical device in the closed configuration. The first motor may be configured to drive the first gear to rotate a first knob. The second motor may be configured to drive the second gear to rotate a second knob.

Abstract: A medical device includes a handle including a stationary body, a first movable body, and a second movable body; a control member coupled to the second movable body; an intermediate sheath coupled to the first movable body; an external sheath coupled to the stationary body; and an end effector. The end effector includes a first loop and a second loop. The first loop includes a first arm and a second arm, and the first arm is coupled to the intermediate sheath. The second arm is coupled to the control member, and the second arm includes a first plurality of teeth. The second loop includes a third arm and a fourth arm. The third arm is coupled to the intermediate sheath, and the fourth arm is coupled to the control member. The fourth arm includes a second plurality of teeth.

Abstract: An implant system and method of delivery includes a catheter system including a sling catheter having a plurality of distal openings and a delivery catheter, disposed within the sling catheter and having a distal port. Suture coupled anchors may be sequentially delivered by the delivery catheter to a cardiac treatment site by aligning the port of the delivery catheter with different openings of the sling catheter and pushing the anchor through the port and the sling catheter to embed the anchor into cardiac tissue such as tissue of a papillary muscle. Each anchor may have a linear configuration for translation within the delivery catheter and a biased configuration that inhibits its reentry into the sling catheter once deployed. Once all anchors are deployed, the suture may be tightened, the anchored portion of the sling catheter may be detached, and the catheter system withdrawn.

Abstract: Medical devices and methods for using medical devices are disclosed. An example medical device includes a catheter having a proximal end region and a distal tip and an array of sealed chambers disposed along the distal tip, wherein each of the chambers includes a distal membrane disposed along an outer surface of the distal tip and a proximal membrane extending radially inward from the outer surface. Further, each proximal membrane is configured to shift between a first position and an expanded position in response to a change in pressure within the chamber.

Abstract: A cell encapsulation device for implantation in a body includes one or more cell encapsulation layers, each of the one or more cell encapsulation layers including at least one membrane and a guide tube. The at least one membrane is semipermeable. The least one membrane forms a chamber for encapsulating cells and at least one access port through the at least one membrane. The guide tube extends into the chamber from the at least one access port. The guide tube includes a porous wall along at least a portion of its length. The guide tube is capable of guiding movement of a catheter within the chamber.

Abstract: A method for removing one or more objects or materials from a body lumen includes delivering a tube and an expandable device to the body lumen to a position proximal to the one or more objects or materials. The expandable device is positioned with a lumen of the tube, and the expandable device includes a lumen extending from a distal portion to a proximal portion. The method further includes proximally retracting the tube such that the expandable device remains in the position proximal to the one or more objects or materials, distally advancing the expandable device such that the distal portion of the expandable device at least partially surrounds the one or more objects or materials, at least partially closing a distal end of the expandable device, and moving the expandable device proximally to remove the expandable device and the one or more objects or materials from the lumen.

Abstract: A medical device may include a main shaft extending from a proximal end to a distal end; an actuator at a proximal portion of the medical device; an end effector positioned at a distal end of the main shaft and comprising a first jaw and a second jaw; a motor; and a torque amplification system. The torque amplification system may include a driveshaft coupled to the motor; a spring coupled to the driveshaft and configured to expand or contract in a proximal or a distal direction relative to the driveshaft; a hammer moveably coupled to the driveshaft; and an anvil coupled to the end effector and abutting the hammer. The anvil may be configured to provide a rotational power output to the end effector to move the first jaw and/or the second jaw.

Abstract: The present disclosure provides a tissue debridement device and describes an example treatment for ANP using the tissue debridement device. The tissue debridement device has a sheath, a distal tip, and a plurality of rotating tines coupled to the distal tip and the sheath. The distal tip can be adjusted to be closer or further from the sheath to change a diameter of the rotating tines, thereby changing a cutting diameter of the tissue debridement device.

Abstract: A mitral valve leaflet repair system may include a delivery catheter having at least one lumen extending proximally from a distal end of the delivery catheter, a plurality of anchor elements disposed within the at least one lumen, each of the plurality of anchor elements being configured to extend through one layer of mitral valve leaflet tissue, and a securing element configured to secure at least two of the plurality of anchor elements together on one side of the mitral valve leaflet tissue. The at least one lumen may include a suction lumen configured to grasp a mitral valve leaflet prior to extending the plurality of anchor elements through one layer of mitral valve leaflet tissue.

Abstract: A cannulation device is adapted to gain access to the patient's common bile duct. In some instances, the cannulation device includes a first guidewire lumen extending through an elongate shaft and terminating at a first oblique guidewire port, and a second guidewire lumen extending through the elongate shaft and terminating at a second oblique guidewire port. In some instances, the cannulation device includes an inflatable balloon that is inflatable from a collapsed configuration to an expanded configuration in which the inflatable balloon is adapted to occlude the patient's pancreatic duct. In some instances, the cannulation device includes an expandable element that is expandable from a collapsed configuration in which the expandable element is disposed within the guidewire lumen and an extended configuration in which a portion of the expandable element extends distally from a guidewire port.

Abstract: A medical system that includes a medical device having an imaging device configured to capture images of a target site. A location of the target site is determined based on the images. The medical device includes a light source configured to direct light onto the location of the target site, and a processor and non-transitory computer readable medium storing instructions that, when executed by the processor, causes the processor to move a sensor of a medical instrument toward the location of the target site based on the sensor detecting the light at the target site.

Abstract: A medical system that includes a medical device having an imaging device configured to capture images of a target site. A location of the target site is determined based on the images. The medical device includes a light source configured to direct light onto the location of the target site, and a processor and non-transitory computer readable medium storing instructions that, when executed by the processor, causes the processor to move a sensor of a medical instrument toward the location of the target site based on the sensor detecting the light at the target site.

Abstract: A medical instrument may include a tube, a sheath provided around and coaxial with the tube, and an inflatable balloon at a distal end of the sheath. The balloon may receive a fluid from a lumen of the sheath, and may have a central opening along a longitudinal axis thereof, and into which the tube extends, a proximal portion, a middle portion adjacent to and distal of the proximal portion, and a distal portion adjacent to and proximal of the middle portion. When the balloon is inflated with the fluid, a maximum diameter of the middle portion may be less than a maximum diameter of the proximal portion, and less than a maximum diameter of the distal portion. The medical instrument may also include an extraction member provided at a distal end of the tube, distal to the balloon, and movable axially relative to the balloon.

Abstract: A medical device may include a main shaft extending from a proximal end to a distal end; an actuator at a proximal portion of the medical device; an end effector positioned at a distal end of the main shaft and comprising a first jaw and a second jaw; a motor; and a torque amplification system. The torque amplification system may include a driveshaft coupled to the motor; a spring coupled to the driveshaft and configured to expand or contract in a proximal or a distal direction relative to the driveshaft; a hammer moveably coupled to the driveshaft; and an anvil coupled to the end effector and abutting the hammer. The anvil may be configured to provide a rotational power output to the end effector to move the first jaw and/or the second jaw.

Abstract: Intravascular imaging devices as well as methods for imaging are disclosed. An example intravascular imaging device may include a catheter shaft. An imaging core may be disposed within the catheter shaft. The imaging core may include a sheath, an imaging emitter/transducer secured relative to the sheath, a reflector, and a wireless rotary motor coupled to the reflector. An antenna may be disposed adjacent to the imaging transducer. A rectenna may be disposed adjacent to the wireless rotary motor.

Abstract: A medical device includes a handle, an elongate shaft extending distally from the handle, the elongate shaft configured to extend through a mouth of a patient and into an upper esophageal pouch of the patient, the elongate shaft having a distal end configured to engage the upper esophageal pouch, and a force absorbing member permitting the elongate shaft to translate axially relative to the handle. The force absorbing member is configured to exert a force along the elongate shaft to apply the force to the upper esophageal pouch. Another medical device includes a tubular member configured to extend through the mouth and into the upper esophageal pouch, a shaft extending distally from the tubular member, and an inflatable member fixedly attached to a distal end of the shaft. The inflatable member is configured to apply a force to the upper esophageal pouch in an inflated configuration.