Patents by Inventor Aidong QU

Aidong QU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODY-DRUG CONJUGATE AND USE THEREOF
    Publication number: 20250049938
    Abstract: A linker, comprising an amino acid unit (RL). The RL comprises -Val-Ala-Q-Gly-Phe-Gly-, wherein Q is a bond, a single amino acid or a dipeptide. By optimizing a polypeptide sequence, the purpose of more effectively releasing small molecule drugs in tumor cells by ADC drugs is achieved. In addition, the present invention further relates to linker drug containing the above-mentioned linker, a conjugate, and the use of the linker drug and the conjugate.
    Type: Application
    Filed: November 30, 2022
    Publication date: February 13, 2025
    Inventors: Aidong QU, Hongyuan LIANG, Wenyan SHEN, Jingye ZHU, Jianhua QIU, Xu ZHOU
  • Anti-HER3 humanized monoclonal antibody
    Patent number: 11965037
    Abstract: Provided is an anti-HER3 humanized monoclonal antibody. The antibody binds HER3 antigen, has high affinity and biological activity and low immunogenicity, and is stable in structure. The antibody can be used for preparing drugs for preventing or treating HER3-related diseases.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: April 23, 2024
    Assignee: SHANGHAI INSTITUTE OF BIOLOGICAL PRODUCTS CO., LTD.
    Inventors: Aidong Qu, Hongyuan Liang, Fanhong Xu, Aoxiang Li, Lina Wu, Jingye Zhu, Jianhua Qiu, Jin Lu, Lin Zhang, Xin Zhao, Xiaofei Song
  • ANTI-HER3 HUMANIZED MONOCLONAL ANTIBODY
    Publication number: 20210277144
    Abstract: Provided is an anti-HER3 humanized monoclonal antibody. The antibody is bound with HER3 antigen, has high affinity and biological activity and low immunogenicity, and is stable in structure. The antibody can be used for preparing drugs for preventing or treating HER3-related diseases.
    Type: Application
    Filed: July 17, 2019
    Publication date: September 9, 2021
    Inventors: Aidong QU, Hongyuan LIANG, Fanhong XU, Aoxiang LI, Lina WU, Jingye ZHU, Jianhua QIU, Jin LU, Lin ZHANG, Xin ZHAO, Xiaofei SONG