Patents by Inventor Aifeng Lü

Aifeng Lü has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical composition for improving dissolution rate of prasugrel and its preparation method
    Patent number: 9050328
    Abstract: A pharmaceutical composition containing prasugrel and its pharmaceutically acceptable salts, and methods for preparing the same are disclosed. The pharmaceutical composition improves the dissolution rate of prasugrel and its salts at high pH by using solid dispersion technology, inclusion technology or adding surfactants.
    Type: Grant
    Filed: April 22, 2011
    Date of Patent: June 9, 2015
    Assignee: Jiangsu Hansoh Pharmaceutical Group Co., Ltd.
    Inventors: Junda Cen, Chun-hong Zhang, Qi Zhang, Aifeng Lü
  • Erythropoietin mimetic peptide derivative and its pharmaceutical salts, the preparation and uses thereof
    Patent number: 8642545
    Abstract: What is provided is EPO mimetic peptide derivatives defined as formula (I) and their pharmaceutical salts, the preparation thereof, wherein R1, R2, R3, R4, R5, n1, n2 are defined as described in description. A composition comprising of an EPO mimetic peptide derivative defined as formula (I) and its pharmaceutical salt. The uses of the derivatives and their pharmaceutical salts, as well as the uses of the compositions described above in treatment of diseases characterized by a deficiency of EPO or a low or defective red blood cell population.
    Type: Grant
    Filed: November 24, 2008
    Date of Patent: February 4, 2014
    Assignee: Jiangsu Hansoh Pharmaceutical Co., Ltd
    Inventors: Aifeng Lü, Changan Sun, Tao Jiang, Wentao Wu, Yali Wang
  • GLP-1 analogues and their pharmaceutical salts and uses
    Patent number: 8614182
    Abstract: This invention discloses GLP-1 analogues and their pharmaceutical salts, wherein the GLP-1 analogue comprises an amino acid sequence of general formula (I), wherein Lys represents a modified lysine with a lipophilic acid. The GLP-1 analogues provided by this invention have the function of human GLP-1, and a longer half-life in vivo compared with the human GLP-1. Uses of such compounds and compositions include treating non-insulin-dependent diabetes, insulin-dependent diabetes, and obesity.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: December 24, 2013
    Assignee: Jiangsu Hansoh Pharmaceuticals Co., Ltd.
    Inventors: Yali Wang, Aifeng Lü, Changan Sun, Hengli Yuan
  • PHARMACEUTICAL COMPOSITION FOR IMPROVING SOLUBILITY OF PRASUGREL AND ITS PREPARATION METHOD
    Publication number: 20130045251
    Abstract: A pharmaceutical composition containing prasugrel and its pharmaceutically acceptable salts, and methods for preparing the same are disclosed. The pharmaceutical composition improves the dissolution rate of prasugrel and its salts at high pH by using solid dispersion technology, inclusion technology or adding surfactants.
    Type: Application
    Filed: April 22, 2011
    Publication date: February 21, 2013
    Applicant: JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD
    Inventors: Junda Cen, Chun-hong Zhang, Qi Zhang, Aifeng Lü
  • GLP-1 ANALOGUES AND THEIR PHARMACEUTICAL SALTS AND USES
    Publication number: 20120196798
    Abstract: This invention discloses GLP-1 analogues and their pharmaceutical salts, wherein the GLP-1 analogue comprises an amino acid sequence of general formula (I), wherein Lys represents a modified lysine with a lipophilic acid. The GLP-1 analogues provided by this invention have the function of human GLP-1, and a longer half-life in vivo compared with the human GLP-1. Uses of such compounds and compositions include treating non-insulin-dependent diabetes, insulin-dependent diabetes, and obesity.
    Type: Application
    Filed: January 31, 2012
    Publication date: August 2, 2012
    Inventors: Yali Wang, Aifeng Lü, Changan Sun, Hengli Yuan
  • GLP-1 ANALOGUES AND THEIR PHARMACEUTICAL SALTS AND USES
    Publication number: 20120129768
    Abstract: This invention discloses GLP-1 analogues and their pharmaceutical salts, wherein the GLP-1 analogue comprises an amino acid sequence of general formula (I), wherein Lys represents a modified lysine with a lipophilic acid. The GLP-1 analogues provided by this invention have the function of human GLP-1, and a longer half-life in vivo compared with the human GLP-1. Uses of such compounds and compositions include treating non-insulin-dependent diabetes, insulin-dependent diabetes, and obesity.
    Type: Application
    Filed: July 29, 2010
    Publication date: May 24, 2012
    Inventors: Yali Wang, Aifeng Lü, Changan Sun, Hengli Yuan
  • ERYTHROPOIETIN MIMETIC PEPTIDE DERIVATIVE AND ITS PHARMACEUTICAL SALTS, THE PREPARATION AND USES THEREOF
    Publication number: 20100323949
    Abstract: What is provided is EPO mimetic peptide derivatives defined as formula (I) and their pharmaceutical salts, the preparation thereof, wherein R1, R2, R3, R4, R5, n1, n2 are defined as described in description. A composition comprising of an EPO mimetic peptide derivative defined as formula (I) and its pharmaceutical salt. The uses of the derivatives and their pharmaceutical salts, as well as the uses of the compositions described above in treatment of diseases characterized by a deficiency of EPO or a low or defective red blood cell population.
    Type: Application
    Filed: November 24, 2008
    Publication date: December 23, 2010
    Applicant: Jiangsu Hansoh Pharmaceutical Co., Ltd.
    Inventors: Aifeng Lü, Changan Sun, Tao Jiang, Wentao Wu, Yali Wang