Patents by Inventor Aifu Chen

Aifu Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 5'-PHOSPHATE MODIFIED NUCLEOSIDE, AND PREPARATION METHOD AND USE THEREOF
    Publication number: 20260218191
    Abstract: The present disclosure relates to the field of biomedicine, and specifically provides a 5?-phosphate modified nucleoside, and a preparation method and use thereof. The present disclosure provides a modified nucleoside compound, wherein the modified nucleoside compound is a compound represented by formula (I), a pharmaceutically acceptable salt thereof, or a stereoisomer thereof. The oligonucleotide comprising the modified nucleoside compound provided by the present disclosure exhibits significantly enhanced drug efficacy.
    Type: Application
    Filed: January 27, 2026
    Publication date: July 30, 2026
    Inventors: Zeao Huang, Gengshen Song, Jie Wang, Shuo Yang, Zhenmin Li, Yang Yang, Fei Yu, Aifu Chen