Patents by Inventor Aih-Jing Chiou

Aih-Jing Chiou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purification of Japanese encephalitis virus
    Patent number: 6207439
    Abstract: This invention provides a process for large-scale purification of living Japanese encephalitis virus (JEV) suitable for use in vaccine preparation from a JEV source, including a JEV-infected cell culture and a JEV-infected mouse brain. The process includes the following steps: (a) obtaining a sample from a JEV-infected mouse brain or a JEV-infected cell culture, (b) subjecting the sample to a preliminary separation to remove cell and cell debris from the sample of step (a), (c) concentrating the sample from step (b) by ultra-filtration to remove substances having molecular weight below 100 kDa, and (d) subjecting the sample concentrate to gel filtration to obtain a substantially pure fraction of JEV.
    Type: Grant
    Filed: March 25, 1997
    Date of Patent: March 27, 2001
    Assignee: Center for Disease Control
    Inventors: Ming-Yi Liau, Ruwen Jou, Aih-Jing Chiou