Patents by Inventor Aihong Huo

Aihong Huo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10294260
    Abstract: Disclosed are a compound represented by formula (I) and a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, W, n are defined as in the present application. Also disclosed is a method for treating cancer, comprising administering to a subject in need thereof a therapeutically effective amount of the compound represented by formula (I) or a pharmaceutically acceptable salt thereof. The compound and a salt thereof according to the present application possess good anticancer and/or antitumor activity, and good water solubility and stability, as well as good tolerance in animal bodies. Also disclosed is a process for preparing a compound represented by formula (I) of the present application.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: May 21, 2019
    Assignee: TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO., LTD.
    Inventors: Hesheng Zhang, Aihong Huo, Zhenzhong Li
  • Publication number: 20170247403
    Abstract: Disclosed are a compound represented by formula (I) and a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, W, n are defined as in the present application.
    Type: Application
    Filed: May 5, 2017
    Publication date: August 31, 2017
    Inventors: Hesheng Zhang, Aihong Huo, Zhenzhong Li
  • Patent number: 9670242
    Abstract: Disclosed are a compound represented by formula (I) and a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, W, n are defined as in the present application. Also disclosed is a method for treating cancer, comprising administering to a subject in need thereof a therapeutically effective amount of the compound represented by formula (I) or a pharmaceutically acceptable salt thereof. The compound and a salt thereof according to the present application possess good anticancer and/or antitumor activity, and good water solubility and stability, as well as good tolerance in animal bodies. Also disclosed is a process for preparing a compound represented by formula (I) of the present application, comprising reacting a compound represented by formula (II) with a compound represented by formula (III) in the presence of a condensation agent to obtain a compound represented by formula (I).
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: June 6, 2017
    Assignee: Tianjin Hemay Oncology Pharmaceutical Co., Ltd.
    Inventors: Hesheng Zhang, Aihong Huo, Zhenzhong Li
  • Publication number: 20150166595
    Abstract: Disclosed are a compound represented by formula (I) and a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, W, n are defined as in the present application.
    Type: Application
    Filed: March 6, 2013
    Publication date: June 18, 2015
    Inventors: Hesheng Zhang, Aihong Huo, Zhenzhong Li
  • Publication number: 20120029036
    Abstract: Disclosed are a composition comprising a pyridyl cyanoguanidine and a cyclodextrin, a cyclodextrin derivative and/or a surfactant with solubilization, process for preparing the same and use thereof.
    Type: Application
    Filed: August 4, 2011
    Publication date: February 2, 2012
    Applicants: Tianjin Michele Sci-Tech Development Co., Ltd., Tianjin Hemay Bio-Tech Co., Ltd.
    Inventors: Hesheng Zhang, Qinghua Zhang, Yingwei Chen, Aihong Huo