Patents by Inventor Aihua (Steven) Chen

Aihua (Steven) Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250148009
    Abstract: Provided are a target retrieval method and device, and a storage medium.
    Type: Application
    Filed: December 16, 2022
    Publication date: May 8, 2025
    Inventors: Di ZHOU, Weijie WANG, Aihua XU, Pengjun WANG, Xiaohong XIE, Minte SONG, Chunyong NIU
  • Publication number: 20250127751
    Abstract: The disclosure belongs to the technical field of medicine, and specifically discloses a traditional Chinese medicine compound preparation for tumors and application thereof. The traditional Chinese medicine compound preparation includes dimethylarsenic acid, indirubin and cordycepin in a concentration ratio of (1-20):(1-10):(1-40). The traditional Chinese medicine compound preparation of the disclosure can be used for treating kinds of tumors, including leukemia, gastric cancer, lung cancer, glioma, papillary thyroid carcinoma, growth hormone adenoma, pituitary adenoma, myeloma, and other malignant tumors. The traditional Chinese medicine compound preparation has significant treatment effect, high safety, and good development prospects.
    Type: Application
    Filed: October 16, 2024
    Publication date: April 24, 2025
    Inventors: Aihua Liang, Jingzhuo Tian, Chenyue Liu
  • Publication number: 20250116664
    Abstract: The invention belongs to the field of biotechnology, in particular, relates to peptide fragment, monoclonal antibody, colloidal gold test strip and detection method thereof used for detection of stichopus oligopeptide. Sequences of the peptide fragments are SEQ ID NO: 1 and SEQ ID NO: 3. After identification, the peptides SEQ ID NO: 1 and SEQ ID NO: 3 are newly discovered oligopeptides, which are exclusive peptide fragments of Stichopus oligopeptide.
    Type: Application
    Filed: October 17, 2024
    Publication date: April 10, 2025
    Inventors: Weiyang BAO, Zuzhe WANG, Aihua ZUO, Pu MA, Tianli SUN, Linying ZHAO
  • Publication number: 20250084715
    Abstract: Provided, in one aspect, is an anchoring subassembly, a well system, and a method. The anchoring subassembly, in one aspect, includes a mandrel, and an isolation element positioned about the mandrel, the isolation element configured to move between a radially retracted state, a fully radially expanded state, and a relaxed radially expanded state. The anchoring subassembly, in one aspect, further includes a ratch latch body coupled to the isolation element, the ratch latch body configured to hold the isolation element in the fully radially expanded state, and a relief feature coupled to the ratch latch body, the relief feature configured to shear to release stored energy in the isolation element and thereby allow the isolation element to move from the fully radially expanded state to the relaxed radially expanded state.
    Type: Application
    Filed: November 26, 2024
    Publication date: March 13, 2025
    Inventors: Aihua Liang, Wesley P. Dietz, Alireza Yazdanshenas
  • Publication number: 20250073170
    Abstract: Provided are high concentration stable formulations of anti-CSF1R/CSF1 antibodies. An example formulation includes 105 to 250 mg/mL of the antibody, 100 mM to 200 mM of arginine glutamate or arginine HCl, 10 mM to 50 mM histidine, and 0.015 to 0.035 w/v % of polysorbate 80, at a pH of 5.4 to 5.6. Also provided are methods of using the formulations for treating diseases.
    Type: Application
    Filed: November 19, 2024
    Publication date: March 6, 2025
    Inventors: Laman Alani, Chung-Chiang HSU, Aihua Zhu, Kirk William Johnson, Michael Huang
  • Publication number: 20250066763
    Abstract: The present disclosure relates, according to some embodiments, to methods for preparing a library for sequencing. For example, a method may comprise (a) in a coupled reaction, (i) contacting a population of nucleic acid fragments with a tailing enzyme to produce tailed fragments, and (ii) ligating to the tailed fragments a sequencing adapter with a ligase to produce adapter-tagged fragments; and/or separating adapter-tagged fragments from the tailing enzyme and the ligase to produce separated adapter-tagged fragments and, optionally, separated tailing enzyme and/or separated ligase. In some embodiments, a tailing enzyme and/or a ligase used in library preparation may be immobilized enzymes.
    Type: Application
    Filed: October 22, 2024
    Publication date: February 27, 2025
    Applicant: New England Biolabs, Inc.
    Inventors: Ming-Qun Xu, Yi Fang, Aihua Zhang, Luo Sun
  • Patent number: 12234292
    Abstract: An antibody or antigen binding fragment thereof that binds to a Fn14, wherein the antibody or antigen binding fragment thereof is an antagonist and non-agonist of Fn14.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: February 25, 2025
    Assignee: KYOWA KIRIN CO., LTD.
    Inventors: Aihua Song, Andrew John McKnight, Rachel Soloff Nugent, John Lorca Laudenslager, Giuseppe Destito, Sarah Sunrise Bubeck, Shinya Ogawa, Yuji Yamazaki, David Mills, Aruna Bitra, Dirk Michael Zajonc
  • Patent number: 12237312
    Abstract: A light-emitting diode (LED) packaging module includes a plurality of LED chips spaced apart from one another, an encapsulating layer that fills in a space among the LED chips, a light-transmitting layer disposed on the encapsulating layer, a wiring assembly disposed on and electrically connected to the LED chips, and an insulation component that covers the encapsulating layer and the wiring assembly. Each of the LED chips includes an electrode assembly including first and second electrodes. The light-transmitting layer includes a light-transmitting layer that has a light transmittance greater than that of the encapsulating layer.
    Type: Grant
    Filed: March 10, 2022
    Date of Patent: February 25, 2025
    Assignee: QUANZHOU SANAN SEMICONDUCTOR TECHNOLOGY CO., LTD.
    Inventors: Shuning Xin, Chen-Ke Hsu, Aihua Cao, Junpeng Shi, Weng-Tack Wong, Yanqiu Liao, Zhen-Duan Lin, Changchin Yu, Chi-Wei Liao, Zheng Wu, Chia-En Lee
  • Patent number: 12233396
    Abstract: A molecular sieve complex contains an oxide of aluminum, an oxide of an alkaline earth metal and a rare earth-modified molecular sieve. The rare earth-modified molecular sieve is a molecular sieve doped by a rare earth element. The percentage of the pore volume occupied by pores of 3 nm or less to the total pore volume in the molecular sieve complex is greater than or equal to 63.5%. The content of the rare earth element and the contents of the oxide of aluminum, the oxide of the alkaline earth metal and the molecular sieve satisfy a certain relationship. The composite material contains a molecular sieve complex and an auxiliary agent loaded on the molecular sieve complex, and the composite material may be applied to flue gas adsorption and desulfurization.
    Type: Grant
    Filed: July 24, 2020
    Date of Patent: February 25, 2025
    Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, SINOPEC QILU COMPANY
    Inventors: Huizhi Yuan, Aihua Liu, Jianli Liu, Cuicui Xu, Zengrang Liu, Weidong Tao, Wenzhi Chang, Caishan Lyu
  • Patent number: 12233397
    Abstract: A composite material is used for desulfurization. The composite material contains activated carbon, alkali metal oxides, silicon oxides, iron oxides, and rare earth element oxides. The weight ratio among the activated carbon, iron oxides and rare earth element oxides is 100:(0.5-5):(1-10). The composite material, used as a sulfur adsorbent, has a higher sulfur breakthrough capacity and desulfurization rate.
    Type: Grant
    Filed: July 24, 2020
    Date of Patent: February 25, 2025
    Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, SINOPEC QILU COMPANY
    Inventors: Cuicui Xu, Aihua Liu, Feng Han, Jianli Liu, Zengrang Liu, Weidong Tao, Wenzhi Chang, Caishan Lyu
  • Patent number: 12230612
    Abstract: A light-emitting diode (LED) packaging module includes light-emitting units arranged in an array having m row(s) and n column(s), an encapsulating layer, and a wiring assembly, where m and n each independently represents a positive integer. Each of the light-emitting units includes LED chips each including a chip first surface, a chip second surface, a chip side surface, and an electrode assembly disposed on the chip second surface. The encapsulating layer covers the chip side surface and fills a space among the LED chips. The wiring assembly is disposed on the chip second surface and is electrically connected to the electrode assembly.
    Type: Grant
    Filed: March 10, 2022
    Date of Patent: February 18, 2025
    Assignee: QUANZHOU SANAN SEMICONDUCTOR TECHNOLOGY CO., LTD.
    Inventors: Shuning Xin, Zhen-Duan Lin, Yanqiu Liao, Junpeng Shi, Aihua Cao, Changchin Yu, Chen-Ke Hsu, Chi-Wei Liao, Chia-En Lee, Zheng Wu
  • Patent number: 12230611
    Abstract: A light-emitting device includes a number (N) of light-emitting units, a number (a) of first metal pads and a number (b) of second metal pads. Each of the light-emitting units includes a number (n) of light-emitting chips each having two distinct terminals, where N and n are integers and N>1, n>?3. The numbers (a) and (b) are integers and a>1, b>1, and the terminals of each of the light-emitting chips are electrically connected to a unique combination of one of the number (a) of first metal pads and a number (b) of second metal pads, respectively. The numbers (N), (n), (a) and (b) satisfy the equation: a*b=n*N.
    Type: Grant
    Filed: February 8, 2022
    Date of Patent: February 18, 2025
    Assignee: QUANZHOU SANAN SEMICONDUCTOR TECHNOLOGY CO., LTD.
    Inventors: Yanqiu Liao, Junpeng Shi, Shuning Xin, Chen-ke Hsu, Zhen-duan Lin, Changchin Yu, Aihua Cao, Chi-Wei Liao, Zheng Wu, Chia-en Lee
  • Publication number: 20250051879
    Abstract: Disclosed herein are magnesium alloy based objects and methods of making and use thereof. For example, disclosed herein are methods of making a magnesium alloy based object, the methods comprising: heating an object comprising a preliminary magnesium alloy at a first temperature for a first amount of time, the preliminary magnesium alloy comprising a first intermetallic phase, a second intermetallic phase, and an alloy phase, to thereby substantially dissolving the first intermetallic phase into the alloy phase to form an object comprising an intermediate magnesium alloy, the intermediate magnesium alloy comprising the second intermetallic phase and the alloy phase; and heating the object comprising the intermediate magnesium alloy at a second temperature for a second amount of time to thereby substantially dissolving the second intermetallic phase into the alloy phase and minimizing incipient melting of the alloy phase to form the magnesium alloy based object.
    Type: Application
    Filed: October 31, 2024
    Publication date: February 13, 2025
    Inventors: Aihua LUO, Thomas AVEY
  • Patent number: 12202831
    Abstract: 2-((1r,4r)-4-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)cyclohexyl)acetonitrile compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions mediated by JAK, such as inflammatory bowel disease.
    Type: Grant
    Filed: June 23, 2021
    Date of Patent: January 21, 2025
    Assignee: Janssen Pharmaceutica NV
    Inventors: Tatiana Koudriakova, Kevin D. Kreutter, Kristi Leonard, Michele C. Rizzolio, Russell C. Smith, Mark S. Tichenor, Aihua Wang
  • Patent number: 12199867
    Abstract: Provided are a method and apparatus for processing a deterministic networking (DetNet) data packet. The method includes: performing, by a DetNet node, format encapsulation on a data packet of a DetNet application flow when the DetNet application flow passes through a multiprotocol label switching (MPLS) network, wherein an encapsulated data packet comprises a label indication and a flow identifier header; and forwarding the encapsulated data packet in the MPLS network.
    Type: Grant
    Filed: October 19, 2020
    Date of Patent: January 14, 2025
    Assignee: ZTE CORPORATION
    Inventors: Jinghai Yu, Chenqiang Gao, Lifeng Rong, Aihua Liu, Quan Xiong
  • Patent number: 12192074
    Abstract: Provided are a data collection method and apparatus, network device, and storage medium. The method includes: receiving, by a first network data analytics function (NWDAF), a first message sent by a consumer, the first message is provided for requesting or subscribing to an NWDAF analytics service, wherein the first message includes a first parameter, the first parameter at least including at least one of: an event identifier (ID), a data collection time parameter, or area information; inquiring, by the first NWDAF through a first network device before starting data collection, whether an existing NWDAF is collecting or has already stored data matching the first parameter, and executing, by the first NWDAF, a corresponding data collection strategy according to an inquiry result.
    Type: Grant
    Filed: September 28, 2021
    Date of Patent: January 7, 2025
    Assignees: China Mobile Communication Co., Ltd Research Institute, China Mobile Communications Group Co., Ltd.
    Inventors: Le Liu, Aihua Li, Bin Wei
  • Publication number: 20250007816
    Abstract: Provided are a method for receiving border gateway protocol (BGP)-intent route, and a method for advertising BGP-intent route. The method for receiving BGP-intent route includes: receiving the BGP-intent route advertised by a BGP speaker, where the BGP-intent route carries at least one of the following: a metric type, a metric and metric credit information.
    Type: Application
    Filed: August 1, 2022
    Publication date: January 2, 2025
    Inventors: Shaofu PENG, Bin TAN, Aihua LIU, Quan XIONG
  • Patent number: 12178915
    Abstract: Provided are high concentration stable formulations of anti-CSF1R/CSF1 antibodies. An example formulation includes 105 to 250 mg/mL of the antibody, 100 mM to 200 mM of arginine glutamate or arginine HCl, 10 mM to 50 mM histidine, and 0.015 to 0.035 w/v % of polysorbate 80, at a pH of 5.4 to 5.6. Also provided are methods of using the formulations for treating diseases.
    Type: Grant
    Filed: May 18, 2022
    Date of Patent: December 31, 2024
    Assignee: AmMax Bio, Inc.
    Inventors: Laman Alani, Chung-Chiang Hsu, Aihua Zhu, Kirk William Johnson, Michael Huang
  • Patent number: D1059237
    Type: Grant
    Filed: June 13, 2024
    Date of Patent: January 28, 2025
    Inventor: Aihua Huang
  • Patent number: D1060461
    Type: Grant
    Filed: October 21, 2024
    Date of Patent: February 4, 2025
    Inventor: Aihua Huang