Patents by Inventor Aihua (Steven) Chen

Aihua (Steven) Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9725521
    Abstract: The present invention discloses a human-derived insecticidal gene and insecticidal peptide encoded by the same and application thereof. The nucleotide sequence of the human-derived insecticidal gene is as represented by SEQ ID NO.1. The amino acid sequence of the insecticidal peptide encoded by this gene is as represented by SEQ ID NO.2. The insecticidal peptide may be expressed through prokaryotic system. The primary culture has binding activity to Cnaphalocrocis medinalis midgut peritrophic membrane specific receptor BBMV. It is obtained without animal immunization and has a short production cycle and a small amino acid sequence. It is suitable for in vitro mass production and may lower the safety risks resulting from wide use of existing Bt toxins and even might substitute Bt to biologically control agricultural pests in the future. It has important scientific and practical significance to reducing the use of insecticides.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: August 8, 2017
    Assignee: JIANGSU ACADEMY OF AGRICULTURAL SCIENCES
    Inventors: Xianjin Liu, Yuan Liu, Yajing Xie, Aihua Wu, Xiao Zhang, Chongxin Xu, Yanyan Zhao, Jianfeng Zhong
  • Publication number: 20170204352
    Abstract: A detergent composition comprises a detergent adjunct ingredient and two or more enzymes. The use of two or more enzymes for releasing or removing soil or stains from an item and a cleaning or laundering method are disclosed.
    Type: Application
    Filed: March 25, 2015
    Publication date: July 20, 2017
    Applicant: Novozymes A/S
    Inventors: Aihua Yan, Nickolass Bitsch Shack
  • Patent number: 9708660
    Abstract: The present invention relates to compositions comprising a porous nanostructure of a known characteristics and a fragment of nucleic acid having a known sequence. Methods of use of the compositions were also provided, for example in DNA amplification, detection, and DNA sequencing.
    Type: Grant
    Filed: February 19, 2013
    Date of Patent: July 18, 2017
    Assignee: NVIGEN, INC.
    Inventors: Aihua Fu, James Zhu
  • Patent number: 9711266
    Abstract: The present invention relates to nanostructures having low-density and porous coatings that surround or are associated with at least one core nanoparticles. The structures are capable of carrying or associating with at least one payload within or on the surface of the nanostructures so that the structures can be used in applications such as medical diagnosis or therapeutic treatment.
    Type: Grant
    Filed: January 23, 2013
    Date of Patent: July 18, 2017
    Assignee: NVIGEN, Inc.
    Inventor: Aihua Fu
  • Publication number: 20170182056
    Abstract: The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
    Type: Application
    Filed: March 2, 2017
    Publication date: June 29, 2017
    Applicant: Janssen Pharmaceutica NV
    Inventors: Kristi A. Leonard, Kent Barbay, James P. Edwards, Kevin D. Kreutter, David A. Kummer, Umar Maharoof, Rachel Nishimura, Maud Urbanski, Hariharan Venkatesan, Aihua Wang, Ronald L. Wolin, Craig R. Woods, Anne Fourie, Xiaohua Xue, Maxwell D. Cummings, Kelly McClure, Virginia Tanis
  • Publication number: 20170175131
    Abstract: The invention provides recombinant DNA molecules and constructs useful for providing efficient transgene sub-cellular localization of proteins in transgenic plants. Recombinant DNA molecules and constructs for conferring herbicide tolerance or resistance to plants are further provided, as well as plants exhibiting herbicide tolerance and methods for producing or utilizing such plants.
    Type: Application
    Filed: December 2, 2016
    Publication date: June 22, 2017
    Inventors: Christine M. Ellis, Michael E. Goley, Clayton T. Larue, Sherry L. LeClere, Qungang Qi, Aihua Shao, Kwan Y. Thai
  • Patent number: 9656267
    Abstract: A magnetic rack includes a bottom plate; a top plate mounted onto the bottom plate, the top plate having therein a first plurality of tube holes for retaining one or more tubes, each tube hole having an opening and a supporting wall extending from the opening between the top plate and the bottom plate; and a second plurality of magnetic assemblies distributed between at least a portion of the first plurality of tube holes, each magnetic assembly being configured to produce a magnetic field in one or more tube holes adjacent thereto.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: May 23, 2017
    Assignee: NVIGEN, INC.
    Inventor: Aihua Fu
  • Patent number: 9659694
    Abstract: Disclosed are a non-oriented electrical steel plate with low iron loss and high magnetic conductivity and a manufacturing process therefor. The casting blank of the steel plate comprises the following components: Si: 0.1-2.0 wt %, Al: 0.1-1.0 wt %, Mn: 0.10-1.0 wt %, C: ?0.005 wt %, P: ?0.2 wt %, S: ?0.005 wt %, N: ?0.005 wt %, the balance being Fe and unavoidable impurities. The magnetic conductivity of the steel plate meets the following relationship formula: ?10+?13+?15?13982?586.5P15/50; ?10+?13+?15?10000, wherein P15/50 is the iron loss at a magnetic induction intensity of 1.5 T at 50 Hz; ?10, ?13, and ?15 are relative magnetic conductivities at induction intensities of 1.0 T, 1.3 T, and 1.5 T at 50 Hz, respectively. The steel plate can be used for manufacturing highly effective and ultra-highly effective electric motors.
    Type: Grant
    Filed: March 27, 2012
    Date of Patent: May 23, 2017
    Assignee: BAOSHAN IRON & STEEL CO., LTD.
    Inventors: Aihua Ma, Bo Wang, Xiandong Liu, Liang Zou, Shishu Xie, Hongxu Hei
  • Patent number: 9653383
    Abstract: A semiconductor device with thick bottom metal comprises a semiconductor chip covered with a top plastic package layer at its front surface and a back metal layer at its back surface, the top plastic package layer surrounds sidewalls of the metal bumps with a top surface of the metal bumps exposing from the top plastic package layer, a die paddle for the semiconductor chip to mount thereon and a plastic package body.
    Type: Grant
    Filed: June 12, 2015
    Date of Patent: May 16, 2017
    Assignee: Alpha & Omega Semiconductor (Cayman), Ltd.
    Inventors: Hamza Yilmaz, Yan Xun Xue, Jun Lu, Ming-Chen Lu, Yan Huo, Aihua Lu
  • Patent number: 9624225
    Abstract: The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating ROR?t activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.
    Type: Grant
    Filed: October 14, 2014
    Date of Patent: April 18, 2017
    Assignee: Janssen Pharmaceutica NV
    Inventors: Kristi A. Leonard, Kent Barbay, James P. Edwards, Kevin D. Kreutter, David A. Kummer, Umar Maharoof, Rachel Nishimura, Maud Urbanski, Hariharan Venkatesan, Aihua Wang, Ronald L. Wolin, Craig R. Woods, Xiaohua Xue, Maxwell D. Cummings, Kelly McClure, Virginia Tanis
  • Publication number: 20170088633
    Abstract: The present invention discloses a human-derived insecticidal gene and insecticidal peptide encoded by the same and application thereof. The nucleotide sequence of the human-derived insecticidal gene is as represented by SEQ ID NO.1. The amino acid sequence of the insecticidal peptide encoded by this gene is as represented by SEQ ID NO.2. The insecticidal peptide may be expressed through prokaryotic system. The primary culture has binding activity to Cnaphalocrocis medinalis midgut peritrophic membrane specific receptor BBMV. It is obtained without animal immunization and has a short production cycle and a small amino acid sequence. It is suitable for in vitro mass production and may lower the safety risks resulting from wide use of existing Bt toxins and even might substitute Bt to biologically control agricultural pests in the future. It has important scientific and practical significance to reducing the use of insecticides.
    Type: Application
    Filed: January 9, 2015
    Publication date: March 30, 2017
    Applicant: JIANGSU ACADEMY OF AGRICULTURAL SCIENCES
    Inventors: Xianjin LIU, Yuan LIU, Yajing XIE, Aihua WU, Xiao ZHANG, Chongxin XU, Yanyan ZHAO, Jianfeng ZHONG
  • Patent number: 9605268
    Abstract: Disclosed is a method for introducing an exogenous DNA by overcoming the restriction modification barrier of the target bacterium. The method includes the steps of 1) co-expressing all DNA-methyltransferase-encoding genes in the genome of the target bacterium in E. coli in which the restriction modification system thereof has been deleted to obtain a recombinant bacterium A, 2) introducing an exogenous DNA molecule into the recombinant bacterium A for in vivo modification so as to obtain a methylation-modified exogenous DNA molecule, and 3) introducing the methylation-modified exogenous DNA molecule into the target bacterium.
    Type: Grant
    Filed: February 21, 2013
    Date of Patent: March 28, 2017
    Assignee: Institute of Microbiology, Chinese Academy of Sciences
    Inventors: Tingyi Wen, Guoqiang Zhang, Aihua Deng
  • Publication number: 20170080430
    Abstract: A magnetic rack includes a bottom plate; a top plate mounted onto the bottom plate, the top plate having therein a first plurality of tube holes for retaining one or more tubes, each tube hole having an opening and a supporting wall extending from the opening between the top plate and the bottom plate; and a second plurality of magnetic assemblies distributed between at least a portion of the first plurality of tube holes, each magnetic assembly being configured to produce a magnetic field in one or more tube holes adjacent thereto.
    Type: Application
    Filed: September 17, 2015
    Publication date: March 23, 2017
    Inventor: Aihua Fu
  • Publication number: 20170073646
    Abstract: The invention provides a micro-organ composite which comprises a core group of cells and an outer layer of cells, wherein the cells of the core group are mesenchymal cells and the cells of the outer layer are epithelial cells or wherein the cells of the core group are epithelial cells and the cells of the outer layer are mesenchymal cells, and wherein the core group of cells is at least partially encapsulated by the outer layer of cells.
    Type: Application
    Filed: November 22, 2016
    Publication date: March 16, 2017
    Inventors: Aihua Guo, Colin Albert Buchanan Jahoda
  • Patent number: 9593396
    Abstract: A tin-containing magnesium-aluminum-manganese (Mg—Al—Mn) based alloy that provides a desired combination of strength and ductility so as to be particularly suited for structural applications. The alloy includes magnesium, aluminum, and manganese in combination and about 0.5% to about 3.5% tin. The tin addition improves strength without substantial loss of ductility.
    Type: Grant
    Filed: May 16, 2007
    Date of Patent: March 14, 2017
    Assignee: GM Global Technology Operations LLC
    Inventors: Aihua A. Luo, Anil K. Sachdev
  • Publication number: 20170015975
    Abstract: A nanocomposition for modulating cell behaviors and methods of uses thereof. The nanocomposition comprises a nanostructure comprising at least one nanoparticle and at least one cell-modulating agent operably linked to the nanostructure. The cell-modulating agent can interact with a molecule on the surface of a cell, wherein the interaction between the cell-modulating agent and the molecule modulates a behavior of the cell, or purify and concentrate a cell population.
    Type: Application
    Filed: February 10, 2015
    Publication date: January 19, 2017
    Inventors: Aihua FU, Hua ZHOU
  • Publication number: 20160368834
    Abstract: Integrated systems are provided for the production of higher hydrocarbon compositions, for example liquid hydrocarbon compositions, from methane using an oxidative coupling of methane system to convert methane to ethylene, followed by conversion of ethylene to selectable higher hydrocarbon products. Integrated systems and processes are provided that process methane through to these higher hydrocarbon products.
    Type: Application
    Filed: March 21, 2016
    Publication date: December 22, 2016
    Inventors: Greg Nyce, Peter Czerpak, Carlos Faz, Jarod McCormick, William Michalak, Bipinkumar Patel, Guido Radaelli, Tim A. Rappold, Ron Runnebaum, Erik C. Scher, Aihua Zhang, Joel Cizeron
  • Patent number: 9512047
    Abstract: Integrated systems are provided for the production of higher hydrocarbon compositions, for example liquid hydrocarbon compositions, from methane using an oxidative coupling of methane system to convert methane to ethylene, followed by conversion of ethylene to selectable higher hydrocarbon products. Integrated systems and processes are provided that process methane through to these higher hydrocarbon products.
    Type: Grant
    Filed: March 21, 2016
    Date of Patent: December 6, 2016
    Assignee: SILURIA TECHNOLOGIES, INC.
    Inventors: Greg Nyce, Peter Czerpak, Carlos Faz, Jarod McCormick, William Michalak, Bipinkumar Patel, Guido Radaelli, Tim A. Rappold, Ron Runnebaum, Erik C. Scher, Aihua Zhang, Joel Cizeron
  • Publication number: 20160341009
    Abstract: An example whipstock assembly includes a whipstock providing a ramped surface and a longitudinal groove defined in the ramped surface. A lead mill is coupled to the whipstock with a shear fastener that provides resilience against premature shearing under torsional loads between the lead mill and the whipstock, while providing susceptibility to shearing under a predetermined axial load.
    Type: Application
    Filed: November 13, 2014
    Publication date: November 24, 2016
    Applicant: HALLIBURTON ENERGY SERVICES, INC.
    Inventors: Michael B. Hussey, David Joe Steele, Aihua Liang
  • Patent number: 9503938
    Abstract: The disclosure discloses a handover method based on a cognitive technology. At least two working areas such as a Primary Working Area (PWA) and a Secondary Working Area (SWA), a RRM and a HOC are configured both in User Equipment (UE) and in a Base Station (BS); after receiving a handover request, according to the current radio environments, the PWA of the BS makes a handover negotiation with the neighboring BSs or with the neighboring BSs and the UE requesting handover, determines the communication parameters satisfying the handover request, and sends the determined communication parameters to the SWA of the BS and the SWA of the UE; the SWA of the BS and the SWA of the UE configure said communication parameters and notify the RRM of the BS after the configuration is finished; the RRM of the BS instructs the HOC of the BS and the HOC of the UE to activate the respective SWAs, and to perform the handover according to the communication parameters configured by the SWA.
    Type: Grant
    Filed: October 22, 2010
    Date of Patent: November 22, 2016
    Assignee: ZTE CORPORATION
    Inventors: Min Wei, Feng Li, Nan Zhao, Kaibo Tian, Aihua Peng, Senbao Guo