Patents by Inventor Aihua Wang

Aihua Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3,4-dihydro-2H-benzo[1,4]oxazine and thiazine derivatives as CETP inhibitors
    Patent number: 8012963
    Abstract: The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: September 6, 2011
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Gee-Hong Kuo, Thomas Rano, Aihua Wang, Catherine Prouty, Keith T. Demarest, Patricia Pelton
  • 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
    Patent number: 8008513
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: August 30, 2011
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Gee-Hong Kuo, Rui Zhang, Aihua Wang, Alan R. DeAngelis
  • HETEROCYCLYL SUBSTITUTED ARYLINDENOPYRIMIDINES AND THEIR USE AS HIGHLY SELECTIVE ADENOSINE A2a RECEPTOR ANTAGONISTS
    Publication number: 20110105493
    Abstract: This invention relates to a novel arylindenopyrimidine, A, and its therapeutic and prophylactic uses. Disorders treated and/or prevented include Parkinson's Disease. wherein X, R2, R3, and R4 are as defined in the specification.
    Type: Application
    Filed: October 19, 2010
    Publication date: May 5, 2011
    Inventors: Paul F. JACKSON, Mark T. Powell, Brian Christopher Shook, Aihua Wang
  • ALKYL SUBSTITUTED ARYLINDENOPYRIMIDINES AND THEIR USE AS HIGHLY SELECTIVE ADENOSINE A2a RECEPTOR ANTAGONISTS
    Publication number: 20110105541
    Abstract: This invention relates to a novel arylindenopyrimidine, A, and its therapeutic and prophylactic uses. Disorders treated and/or prevented include Parkinson's Disease. wherein X, R2, R3, and R4 are as defined in the specification.
    Type: Application
    Filed: October 19, 2010
    Publication date: May 5, 2011
    Inventors: Paul F. Jackson, Mark T. Powell, Brian Christopher Shook, Aihua Wang
  • ARYL SUBSTITUTED ARYLINDENOPYRIMIDINES AND THEIR USE AS HIGHLY SELECTIVE ADENOSINE A2a RECEPTOR ANTAGONISTS
    Publication number: 20110105492
    Abstract: This invention relates to a novel arylindenopyrimidine, A, and its therapeutic and prophylactic uses. Disorders treated and/or prevented include Parkinson's Disease wherein X, R2, R3, and R4 are as defined in the specification.
    Type: Application
    Filed: October 19, 2010
    Publication date: May 5, 2011
    Inventors: Paul F. Jackson, Mark T. Powell, Brian Christopher Shook, Aihua Wang
  • HETEROARYL SUBSTITUTED ARYLINDENOPYRIMIDINES AND THEIR USE AS HIGHLY SELECTIVE ADENOSINE A2A RECEPTOR ANTAGONISTS
    Publication number: 20110105494
    Abstract: This invention relates to a novel arylindenopyrimidine, A, and its therapeutic and prophylactic uses. Disorders treated and/or prevented include Parkinson's Disease. wherein X, R2, R3, and R4 are as defined in the specification.
    Type: Application
    Filed: October 19, 2010
    Publication date: May 5, 2011
    Inventors: Paul F. JACKSON, Mark T. Powell, Brian Christopher Shook, Aihua Wang
  • 1,2,3,4-tetrahydro-quinoline derivatives as CETP inhibitors
    Patent number: 7928238
    Abstract: The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.
    Type: Grant
    Filed: May 10, 2007
    Date of Patent: April 19, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Thomas Rano, Gee-Hong Kuo, Ellen Sieber-McMaster, Keith T. Demarest, Patricia Pelton, Aihua Wang
  • 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
    Patent number: 7875744
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: January 25, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Gee-Hong Kuo, Rui Zhang, Aihua Wang, Alan DeAngelis, Keith Demarest, Patricia Pelton
  • 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS
    Publication number: 20100331406
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Application
    Filed: September 1, 2010
    Publication date: December 30, 2010
    Inventors: Alan DEANGELIS, Keith T. Demarest, Gee-Hong Kuo, Patricia Pelton, Aihua Wang, Rui Zhang
  • 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
    Patent number: 7812053
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Grant
    Filed: September 14, 2005
    Date of Patent: October 12, 2010
    Assignee: Janssen Pharmaceuticals NV
    Inventors: Alan DeAngelis, Keith T. Demarest, Gee-Hong Kuo, Patricia Pelton, Aihua Wang, Rui Zhang
  • 3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE AND THIAZINE DERIVATIVES AS CETP INHIBITORS
    Publication number: 20100227857
    Abstract: The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.
    Type: Application
    Filed: May 18, 2010
    Publication date: September 9, 2010
    Inventors: Gee-Hong Kuo, Thomas Rano, Aihua Wang, Catherine Prouty, Keith T. Demarest, Patricia Pelton
  • 3,4-dihydro-2h-benzo[1,4]oxazine and thiazine derivatives as CETP inhibitors
    Patent number: 7749995
    Abstract: The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.
    Type: Grant
    Filed: May 10, 2007
    Date of Patent: July 6, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Gee-Hong Kuo, Aihua Wang, Thomas Rano, Catherine Prouty, Keith T. Demarest, Patricia Pelton
  • HETEROARYL SUBSTITUTED THIENO[2,3-d]PYRIMIDINE AND THEIR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS
    Publication number: 20100093756
    Abstract: This invention relates to a novel thieno[2,3-d]pyrimidine, Z, and its therapeutic and prophylactic uses, wherein X, R1 and R2 are defined in the specification. Disorders treated and/or prevented include Parkinson's Disease.
    Type: Application
    Filed: July 8, 2009
    Publication date: April 15, 2010
    Inventors: J. Kent Berbay, Devraj Chakravarty, Kristi Leonard, Brian Christopher Shook, Aihua Wang
  • PHENYL AND HETEROARYL SUBSTITUTED THIENO[2,3-d]PYRIMIDINES AND THEIR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS
    Publication number: 20100093721
    Abstract: This invention relates to a novel thieno[2,3-d]pyrimidine, Z, and its therapeutic and prophylactic uses, wherein X, R1 and R2 are defined in the specification. Disorders treated and/or prevented include Parkinson's Disease.
    Type: Application
    Filed: June 5, 2009
    Publication date: April 15, 2010
    Inventors: J. Kent Barbay, Devraj Chakravarty, Kristi Leonard, Brian Christopher Shook, Aihua Wang
  • METHYLENE AMINES OF THIENO[2,3-d]PYRIMIDINE AND THEIR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS
    Publication number: 20100093702
    Abstract: This invention relates to a novel thieno[2,3-d]pyrimidine, A, and its therapeutic and prophylactic uses, wherein R1 and R2 are defined in the specification. Disorders treated and/or prevented include Parkinson's Disease.
    Type: Application
    Filed: June 5, 2009
    Publication date: April 15, 2010
    Inventors: J. Kent Barbay, Devraj Chakravarty, Brian Christopher Shook, Aihua Wang
  • HETEROARYL AND PHENYL SUBSTITUTED THIENO[2,3-d]PYRIMIDINES AND THEIR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS
    Publication number: 20100093722
    Abstract: This invention relates to a novel thieno[2,3-d]pyrimidine, Z, and its therapeutic and prophylactic uses, wherein R1 and R2 are defined in the specification. Disorders treated and/or prevented include Parkinson's Disease.
    Type: Application
    Filed: July 8, 2009
    Publication date: April 15, 2010
    Inventors: J. Kent BARBAY, Devraj Chakravarty, Kristi Leonard, Brian Christopher Shook, Aihua Wang
  • PHENYL SUBSTITUTED THIENO[2,3-d]PYRIMIDINES AND THEIR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS
    Publication number: 20100093763
    Abstract: This invention relates to a novel thieno[2,3-d]pyrimidine, Z, and its therapeutic and prophylactic uses, wherein R1 and R2 are defined in the specification. Disorders treated and/or prevented include Parkinson's Disease.
    Type: Application
    Filed: July 8, 2009
    Publication date: April 15, 2010
    Inventors: J. Kent Barbay, Devraj Chakravarty, Kristi Leonard, Brian Christopher Shook, Aihua Wang
  • HETEROCYCLYL AND CYCLOALKYL SUBSTITUTED THIENO[2,3 d]PYRIMIDINE AND THEIR USE AS ADENOSINE A2a RECEPTOR ANTAGONISTS
    Publication number: 20100093723
    Abstract: This invention relates to a novel thieno[2,3-d]pyrimidine, Z, and its therapeutic and prophylactic uses, wherein X, R1 and R2 are defined in the specification. Disorders treated and/or prevented include Parkinson's Disease.
    Type: Application
    Filed: July 8, 2009
    Publication date: April 15, 2010
    Inventors: J. Kent Barbay, Devraj Chakravarty, Kristi Leonard, Brian Christopher Shook, Aihua Wang
  • 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS
    Publication number: 20100069496
    Abstract: The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
    Type: Application
    Filed: November 23, 2009
    Publication date: March 18, 2010
    Inventors: Gee-Hong Kuo, Rui Zhang, Aihua Wang, Alan R. DeAngelis
  • SIRE EARLY SELECTION FOR MALE FERTILITY USING SINGLE NUCLEOTIDE POLYMORPHISMS (SNPS) OF THE DAZL GENE
    Publication number: 20100009374
    Abstract: Methods and materials for identifying bovine males which will produce semen which will exhibit a higher rate of successfully impregnation by either artificial insemination or natural mating. The method employs SNPs that have been identified in the bDAZL gene which are associated with enhanced (or decreased) male fertility in bovine males and haplotypes formed from such SNPs. The method herein can be used to identify male dairy or beef cattle. The method herein can be applied to bovine animals at an appropriate time and particularly at birth or in utero. The invention further provides kits for conduction assays to assess bovine male fertility/infertility. The invention additionally provides a method of breeding cattle employing the methods and materials herein.
    Type: Application
    Filed: January 11, 2008
    Publication date: January 14, 2010
    Inventors: Wansheng Liu, Aihua Wang