Abstract: A rocuronium bromide injection solution-prefilled syringe of the present invention includes a syringe comprising an outer cylinder made of synthetic resin, a gasket which is accommodated inside the outer cylinder and liquid-tightly slidable inside the outer cylinder, and a seal member for sealing a distal end opening of the outer cylinder; and a rocuronium bromide injection solution filled inside the syringe. The gasket is formed by vulcanized chlorinated butyl rubber added calcined clay, and said calcined clay is only added as an inorganic filler classified as an inorganic reinforcing agent and an inorganic filling agent.

Abstract: A remifentanil injection solution formulation contains remifentanil and or physiologically acceptable salts thereof, water, and a stabilizer, the remifentanil injection solution formulation contains said water at a rate of 0.007 to 0.025 mL per 1 mg of said remifentanil.

Abstract: A syringe barrel includes an barrel main body having a female luer at a distal end of the barrel main body, the female luer being configured such that a male luer is insertable into and connectable to the female luer; and a cap that is detachably attached to the female luer to close an opening of the female luer. The female luer has a female luer-side connector, and the cap is detachably attached to the female luer via the female luer-side connector. The cap includes an insertion part inserted into the female luer, a sealing part that seals the opening of the female luer, and a cap-side connector that is detachably engaged with the female luer-side connector.

Abstract: A remifentanil injection formulation contains remitentanil and/or physiologically acceptable salts of said remifentanil and a colorant selected from among cyanocobalamin, indocyanine green, and indigocarmine.

Abstract: A remifentanil injection solution formulation contains remifentanil and or physiologically acceptable salts thereof, water, and a stabilizer, the remifentanil injection solution formulation contains said water at a rate of 0.007 to 0.025 mL per 1 mg of said remifentanil.

Abstract: A rocuronium bromide injection solution-prefilled syringe of the present invention includes a syringe comprising an outer cylinder made of synthetic resin, a gasket which is accommodated inside the outer cylinder and liquid-tightly slidable inside the outer cylinder, and a seal member for sealing a distal end opening of the outer cylinder; and a rocuronium bromide injection solution filled inside the syringe. The gasket is formed by vulcanized chlorinated butyl rubber added calcined clay, and said calcined clay is only added as an inorganic filler classified as an inorganic reinforcing agent and an inorganic filling agent.

Abstract: A syringe barrel includes a cylindrical main body portion configured to allow liquid-tight sliding of a gasket; and a hollow distal end portion configured to extend distally from the cylindrical main body portion. The distal end portion includes: a hollow small-diameter distal end portion having a puncture end portion configured to be inserted into a puncturable portion of a medical device having a female luer taper; and a large-diameter portion having a diameter larger than a diameter of the small-diameter distal end portion, an outer surface of the large-diameter portion being tapered such that the outer diameter of the large-diameter portion increases from a distal end to a proximal end thereof. The large-diameter portion is configured to connect to a connection portion of the medical device. The small-diameter distal end portion is housed in the connection portion upon connection of the large-diameter portion to the connection portion.

Abstract: A syringe barrel includes an barrel main body having a female luer at a distal end of the barrel main body, the female luer being configured such that a male luer is insertable into and connectable to the female luer; and a cap that is detachably attached to the female luer to close an opening of the female luer. The female luer has a female luer-side connector, and the cap is detachably attached to the female luer via the female luer-side connector. The cap includes an insertion part inserted into the female luer, a sealing part that seals the opening of the female luer, and a cap-side connector that is detachably engaged with the female luer-side connector.

Abstract: A gasket for use in a syringe so formed as to liquid-tightly and slidably contact an inner surface of an outer cylinder of the syringe, the gasket including a gasket body made of an elastic body and a coating layer formed on a portion thereof which contacts at least the syringe, wherein the coating layer includes a composition containing a silicone resin which includes a condensate of a reactive silicone resin having a terminal silanol group and which has a siloxane bond derived from the silanol group, and does not contain solid fine particles.

Abstract: A gasket for use in a syringe so formed as to liquid-tightly and slidably contact an inner surface of an outer cylinder of the syringe, the gasket including a gasket body made of an elastic body and a coating layer formed in a portion thereof which contacts at least the syringe, wherein the coating layer includes a composition containing silicone resin which includes a condensate of reactive silicone resin having a terminal silanol group and which has a siloxane bond derived from the silanol group, and does not contain solid fine particles.

Abstract: A gasket for use in a syringe so formed as to liquid-tightly and slidably contact an inner surface of an outer cylinder of the syringe, the gasket including a gasket body made of an elastic body and a coating layer formed on a portion thereof which contacts at least the syringe, wherein the coating layer includes a composition containing a silicone resin which comprises a condensate of a reactive silicone resin having a terminal silanol group and which has a siloxane bond derived from the silanol group, and does not contain solid fine particles.

Abstract: A gasket for use in a syringe so formed as to liquid-tightly and slidably contact an inner surface of an outer cylinder of the syringe, the gasket including a gasket body made of an elastic body and a coating layer formed in a portion thereof which contacts at least the syringe, wherein the coating layer includes a composition containing silicone resin which comprises a condensate of reactive silicone resin having a terminal silanol group and which has a siloxane bond derived from the silanol group, and does not contain solid fine particles.

Abstract: An metalloporphyrin-complex-embedded liposome, comprising a cationic metalloporphyrin complex and a lipid having liposome forming ability is disclosed. As metalloporphyrin-complex-embedded liposomes according to the present invention act on superoxide anion radicals (O2?), and can surely lower their concentration, they can exhibit superb effects for the treatment of cancers and have excellent characteristics as antioxidants.