Patents by Inventor Aileen HÖHNE

Aileen HÖHNE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF
    Publication number: 20230212549
    Abstract: The present invention is related to a compound comprising a cyclic peptide of formula (I) and an N-terminal modification group A attached to Xaa1, wherein each and any one of Xaa1, Xaa2, Xaa3, Xaa4, Xaa5, Xaa6 and Xaa7 is a residue of an amino acid, and Yc is a structure of formula (X)
    Type: Application
    Filed: January 7, 2022
    Publication date: July 6, 2023
    Applicant: 3B PHARMACEUTICALS GMBH
    Inventors: Frank OSTERKAMP, Dirk ZBORALSKI, Eberhard SCHNEIDER, Christian HAASE, Matthias PASCHKE, Aileen HÖHNE, Jan UNGEWIß, Christiane SMERLING, Ulrich REINEKE, Anne BREDENBECK, Jan Lennart von Hacht
  • COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF
    Publication number: 20220315554
    Abstract: The present invention is related to a compound comprising a cyclic peptide of formula (I) and an N-terminal modification group A attached to Xaa1, wherein each and any one of Xaa1, Xaa2, Xaa3, Xaa4, Xaa5, Xaa6 and Xaa7 is a residue of an amino acid, and Yc is a structure of formula (X)
    Type: Application
    Filed: July 8, 2020
    Publication date: October 6, 2022
    Applicant: 3B PHARMACEUTICALS GMBH
    Inventors: Frank OSTERKAMP, Dirk ZBORALSKI, Eberhard SCHNEIDER, Christian HAASE, Matthias PASCHKE, Aileen HÖHNE, Jan UNGEWISS, Christiane SMERLING, Ulrich REINEKE, Anne BREDENBECK
  • COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF
    Publication number: 20220273831
    Abstract: The present invention is related to a compound comprising a cyclic peptide and a chelator, and its use.
    Type: Application
    Filed: July 8, 2020
    Publication date: September 1, 2022
    Inventors: Frank OSTERKAMP, Dirk ZBORALSKI, Eberhard SCHNEIDER, Christian HAASE, Matthias PASCHKE, Aileen HÖHNE, Jan UNGEWISS, Christiane SMERLING, Ulrich REINEKE, Anne BREDENBECK
  • MULTI-MODALITY MOLECULAR IMAGING HIGH-THROUGHPUT ASSAY FOR IDENTIFYING HEAT SHOCK PROTEIN 90 (HSP90) INHIBITORS
    Publication number: 20130310347
    Abstract: High throughput methods for identifying novel inhibitors of Hsp90 chaperone protein folding are disclosed. The inhibitors so identified disrupt the binding of p23 to either Hsp90? or Hsp90? and have selective activity against the proliferation of cancer cells. In particular are provided embodiments of therapeutic compositions that comprise at least one inhibitor of an Hsp90 chaperone activity, the inhibitor being any of the compounds designated as CP1-CP19 as shown in FIGS. 1A-1D or a 2-(trifluoromethyl)pyrimidin-2-yl)thio)acetamide derivatives.
    Type: Application
    Filed: May 21, 2013
    Publication date: November 21, 2013
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Carmel Chan, Sanjiv S. Gambhir, David E. Solow-Cordero, Aileen Hoehne, Ramasamy Paulmurugan