Patents by Inventor Ailette Mulet Sierra

Ailette Mulet Sierra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monoclonal antibody which recognizes the oligosaccharide N-glycolylated-galactose-glucose sialic acid in malignant tumors, and composition containing it
    Patent number: 6429295
    Abstract: The present invention is related with the field of immunology and human medicine, particularly with the generation and selection of a monoclonal antibody (Mab) that recognizes the N-glycolylated-galactose-glucose sialic acid olygosaccharide sequence presents in malignant tumors. One of the objectives of this invention is to provide a Mab of the IgG1 type that has the characteristic of recognizing with high specificity N-glycolylated-galactose-glucose sialic acid olygosaccharide sequence presents in malignant tissues of breast, melanomas and tumors of the liver, stomach, colon, rectum and kidneys. It also has the capacity of producing direct cytolysis of the tumoral cells bearing the N-glycolylated-galactose-glucose sialic acid olygosaccharide sequence, thus can be used for the diagnosis and treatment of certain neoplasic diseases.
    Type: Grant
    Filed: November 22, 1999
    Date of Patent: August 6, 2002
    Assignee: Centro de Inmunologia Molecular (CIM)
    Inventors: Adriana Carr Pérez, Zaima Mazorra Herrera, Luis Enrique Fernández Molina, Ana Maria Vázquez López, Ailette Mulet Sierra, Rolando Pérez Rodríguez