Patents by Inventor Ailsa Grigg

Ailsa Grigg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isothermal strand displacement amplification using primers containing a non-regular base
    Patent number: 8431347
    Abstract: The invention is directed to a method for isothermal DNA amplification comprising providing to the DNA to be amplified an amplification mix comprising a first primer at least partially complementary to a region of DNA and containing a non-regular base, a second primer at least partially complementary to a region of DNA and containing a non- regular base, a DNA polymerase, an enzyme capable of strand displacement, an enzyme that recognises a non-regular base in double-stranded DNA and causes a nick or excises a base in one DNA strand at or near the non-regular base; and amplifying the DNA substantially without thermal cycling.
    Type: Grant
    Filed: May 25, 2006
    Date of Patent: April 30, 2013
    Assignee: Human Genetic Signatures Pty Ltd
    Inventors: Douglas Spencer Millar, John R. Melki, Ailsa Grigg
  • Isothermal Strand Displacement Amplification Using Primers Containing a Non-Regular Base
    Publication number: 20100221785
    Abstract: The invention is directed to a method for isothermal DNA amplification comprising providing to the DNA to be amplified an amplification mix comprising a first primer at least partially complementary to a region of DNA and containing a non-regular base, a second primer at least partially complementary to a region of DNA and containing a non-regular base, a DNA polymerase, an enzyme capable of strand displacement, an enzyme that recognises a non-regular base in double-stranded DNA and causes a nick or excises a base in one DNA strand at or near the non-regular base; and amplifying the DNA substantially without thermal cycling.
    Type: Application
    Filed: May 25, 2006
    Publication date: September 2, 2010
    Applicant: HUMAN GENETIC SIGNATURES PTY LTD
    Inventors: Douglas Spencer Millar, John R. Melki, Geoffrey W. Grigg, Ailsa Grigg