Patent number: 6420413
Abstract: A compound selected from those of formula (I):
wherein:
denotes single bond or double bond,
n is integer from 1 to 6 inclusive,
R1, and R2 represent a group selected from hydrogen, linear or branched (C1-C6)-alkyl, aryl, arylalkyl, cycloalkyl, cycloalkylalkyl, alkenyl, alkynyl, heterocycloalkyl, heterocycloalkylalkyl, heteroaryl, and heteroarylalkyl,
X represents a group selected from —CH═CH—, oxygen, S(O)m wherein m is integer from 0 to 2 inclusive, and NR3 wherein R3 represents a group as defined in the description,
Y represents CH or CH2 depending on whether
denotes single bond or double bond, or may have the additional meaning of oxygen when X represents oxygen,
T represents monocyclic or polycyclic (C3-C10)cycloalkyl optionally containing within the ring system oxygen, selenium, S(O)p, NR3, or SiR4R5 wherein p, R3, R4, and R5 are as defined in the description,
its isomers and addition salts thereof with a pharmaceutically-accep
Type:
Grant
Filed:
April 12, 2001
Date of Patent:
July 16, 2002
Assignee:
Les Laboratories Servier
Inventors:
Jean-Louis Peglion, Aimée Dessinges, Bertrand Goument, Mark Millan, Françoise Lejeune, Mauricette Brocco