Patents by Inventor Aimee B. Angel
Aimee B. Angel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8246582Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, and a needle with a bore extending along the length of the needle from a first end of the needle to a second end of the needle. The second end is substantially aligned to a plane parallel to a body surface of a biological body when the device is placed on the body surface. The device also includes an actuator which pumps the formulation through the bore of the needle between a target area of the body and the reservoir.Type: GrantFiled: April 29, 2008Date of Patent: August 21, 2012Assignee: Massachusetts Institute of TechnologyInventors: Aimee B. Angel, Ian W. Hunter
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Patent number: 7651475Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, and an array of needles which have bores in fluid communication with the reservoir to facilitate transporting the formulation to and from the reservoir through the needles. The device also includes a first actuator which drives the array of needles into the body, and a second actuator which pumps the formulation between the reservoir and the body through the needles. The first actuator is reversible to withdraw the needles from the body.Type: GrantFiled: January 11, 2008Date of Patent: January 26, 2010Assignee: Massachusetts Institute of TechnologyInventors: Aimee B. Angel, Ian W. Hunter
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Patent number: 7645263Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, a needle with a bore through which the formulation is transported between the reservoir and a target area of a biological body, and an impedance sensor. The impedance sensor has an electrode positioned to measure the impedance of a portion of the target area between the needle and the electrode to indicate the depth of penetration of the needle into the target area.Type: GrantFiled: October 21, 2002Date of Patent: January 12, 2010Assignee: Massachusetts Institute of TechnologyInventors: Aimee B. Angel, Ian W. Hunter, Laura L. Proctor, James Tangorra
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Publication number: 20080319392Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, and an array of needles which have bores in fluid communication with the reservoir to facilitate transporting the formulation to and from the reservoir through the needles. The device also includes a first actuator which drives the array of needles into the body, and a second actuator which pumps the formulation between the reservoir and the body through the needles. The first actuator is reversible to withdraw the needles from the body.Type: ApplicationFiled: January 11, 2008Publication date: December 25, 2008Inventors: Aimee B. Angel, Ian W. Hunter
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Publication number: 20080281273Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, and a needle with a bore extending along the length of the needle from a first end of the needle to a second end of the needle. The second end is substantially aligned to a plane parallel to a body surface of a biological body when the device is placed on the body surface. The device also includes an actuator which pumps the formulation through the bore of the needle between a target area of the body and the reservoir.Type: ApplicationFiled: April 29, 2008Publication date: November 13, 2008Applicant: Massachusetts Institute of TechnologyInventors: Aimee B. Angel, Ian W. Hunter
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Patent number: 7429258Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, and an array of needles which have bores in fluid communication with the reservoir to facilitate transporting the formulation to and from the reservoir through the needles. The device also includes a first actuator which drives the array of needles into the body, and a second actuator which pumps the formulation between the reservoir and the body through the needles. The first actuator is reversible to withdraw the needles from the body.Type: GrantFiled: September 9, 2002Date of Patent: September 30, 2008Assignee: Massachusetts Institute of TechnologyInventors: Aimee B. Angel, Ian W. Hunter
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Patent number: 7425204Abstract: An injector includes a housing having a chamber for holding a liquid formulation of an active principle to be injected into a biological body and an output port in fluid communication with the chamber through which the liquid formulation is injected. A piston is positioned within the housing, and includes an end portion with substantially the same shape as the chamber. A magnetic force draws the piston and housing together to expel the liquid formulation out of the chamber through the output port.Type: GrantFiled: April 28, 2005Date of Patent: September 16, 2008Assignee: Massachusetts Institute of TechnologyInventors: Aimee B. Angel, Ian W. Hunter
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Patent number: 7364568Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, and a needle with a bore extending along the length of the needle from a first end of the needle to a second end of the needle. The second end is substantially aligned to a plane parallel to a body surface of a biological body when the device is placed on the body surface. The device also includes an actuator which pumps the formulation through the bore of the needle between a target area of the body and the reservoir.Type: GrantFiled: October 21, 2002Date of Patent: April 29, 2008Assignee: Massachusetts Institute of TechnologyInventors: Aimee B. Angel, Ian W. Hunter
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Patent number: 7066922Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, and one or more needles. Each needle has a bore through which the formulation is transported between the reservoir and a biological body, and has an end portion that is substantially aligned in a plane parallel to a surface of the biological body when the device is placed on the surface. The device also includes a vacuum generator which creates a suction to draw a portion of the surface beyond the plane of the end portions to enable the end portions to penetrate the portion of the surface as the needles are translated along an axis that is substantially parallel to the plane.Type: GrantFiled: October 21, 2002Date of Patent: June 27, 2006Assignee: Massachusetts Institute of TechnologyInventors: Aimee B. Angel, Ian W. Hunter, Peter Hansen
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Patent number: 6939323Abstract: An injector includes a housing having a chamber for holding a liquid formulation of an active principle to be injected into a biological body and an output port in fluid communication with the chamber through which the liquid formulation is injected. A piston is positioned within the housing, and includes an end portion with substantially the same shape as the chamber. A magnetic force draws the piston and housing together to expel the liquid formulation out of the chamber through the output port.Type: GrantFiled: July 19, 2002Date of Patent: September 6, 2005Assignee: Massachusetts Institute of TechnologyInventors: Aimee B. Angel, Ian W. Hunter
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Publication number: 20030139727Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, and one or more needles. Each needle has a bore through which the formulation is transported between the reservoir and a biological body, and has an end portion that is substantially aligned in a plane parallel to a surface of the biological body when the device is placed on the surface. The device also includes a vacuum generator which creates a suction to draw a portion of the surface beyond the plane of the end portions to enable the end portions to penetrate the portion of the surface as the needles are translated along an axis that is substantially parallel to the plane.Type: ApplicationFiled: October 21, 2002Publication date: July 24, 2003Applicant: Massachusetts Institute of TechnologyInventors: Aimee B. Angel, Ian W. Hunter, Peter Hansen
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Publication number: 20030083641Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, a needle with a bore through which the formulation is transported between the reservoir and a target area of a biological body, and an impedance sensor. The impedance sensor has an electrode positioned to measure the impedance of a portion of the target area between the needle and the electrode to indicate the depth of penetration of the needle into the target area.Type: ApplicationFiled: October 21, 2002Publication date: May 1, 2003Applicant: Massachusetts Institute of TechnologyInventors: Aimee B. Angel, Ian W. Hunter, Laura L. Proctor, James Tangorra
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Publication number: 20030083611Abstract: An injector includes a housing having a chamber for holding a liquid formulation of an active principle to be injected into a biological body and an output port in fluid communication with the chamber through which the liquid formulation is injected. A piston is positioned within the housing, and includes an end portion with substantially the same shape as the chamber. A magnetic force draws the piston and housing together to expel the liquid formulation out of the chamber through the output port.Type: ApplicationFiled: July 19, 2002Publication date: May 1, 2003Applicant: Massachusetts Institute of TechnologyInventors: Aimee B. Angel, Ian W. Hunter
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Publication number: 20030083619Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, and a needle with a bore extending along the length of the needle from a first end of the needle to a second end of the needle. The second end is substantially aligned to a plane parallel to a body surface of a biological body when the device is placed on the body surface. The device also includes an actuator which pumps the formulation through the bore of the needle between a target area of the body and the reservoir.Type: ApplicationFiled: October 21, 2002Publication date: May 1, 2003Applicant: Massachusetts Institute of TechnologyInventors: Aimee B. Angel, Ian W. Hunter
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Publication number: 20030083645Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, and an array of needles which have bores in fluid communication with the reservoir to facilitate transporting the formulation to and from the reservoir through the needles. The device also includes a first actuator which drives the array of needles into the body, and a second actuator which pumps the formulation between the reservoir and the body through the needles. The first actuator is reversible to withdraw the needles from the body.Type: ApplicationFiled: September 9, 2002Publication date: May 1, 2003Applicant: Massachusetts Institute of TechnologyInventors: Aimee B. Angel, Ian W. Hunter
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Publication number: 20030083618Abstract: A transdermal transport device includes a reservoir for holding a formulation of an active principle, a needle with a bore through which the formulation is transported between the reservoir and a target area of a biological body, and an electrolytic actuator which pumps the formulation through the bore.Type: ApplicationFiled: October 21, 2002Publication date: May 1, 2003Applicant: Massachusetts Institute of TechnologyInventors: Aimee B. Angel, Ian W. Hunter, Peter Madden