Patents by Inventor Aimee Rose

Aimee Rose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230167497
    Abstract: Methods of identifying agents that modulate the interleukin-17 (IL-17) pathway are described. Said methods use detecting a level of granulocyte colony-stimulating factor (G-CSF) in a cell supernatant and/or detecting an expression level of one gene or a panel of genes of a cell treated with an agent. Also described are probes capable of detecting a gene or panel of genes and kits for identifying agents that modulate the IL-17 pathway.
    Type: Application
    Filed: April 28, 2021
    Publication date: June 1, 2023
    Inventors: Katherine Y. Blain, Aimee Rose de Leon-Tabaldo, Anne M. Fourie, Steven Goldberg, Xuejun Liu, Rosa Luna-Roman, Michael Angelo Rodriguez, Xiaohua Xue
  • Publication number: 20220365100
    Abstract: Methods to measure total IL-17 in a biological sample comprising the IL-17 and a large molecule modulator of IL-17.
    Type: Application
    Filed: September 28, 2020
    Publication date: November 17, 2022
    Inventors: Jonathan M. BLEVITT, Aimee Rose DE LEON-TABALDO, Wai-Ping LEUNG, Xiaohua XUE
  • Publication number: 20220357341
    Abstract: Methods to measure free IL-17 in a sample comprising IL-17 and a small molecule modulator of IL-17.
    Type: Application
    Filed: September 28, 2020
    Publication date: November 10, 2022
    Inventors: Jonathan M. BLEVITT, Aimee Rose DE LEON-TABALDO, Samuel E. DEPRIMO, Steven GOLDBERG, Wai-Ping LEUNG, Amy STRASNER, Xiaohua XUE
  • Patent number: 10338000
    Abstract: There is provided a sensor fiber including an electrically insulating material having a fiber length. At least one transduction element is disposed along at least a portion of the fiber length and is arranged for exposure to an intake species. A photoconducting element is in optical communication with the transduction element. At least one pair of electrically conducting electrodes are in electrical connection with the photoconducting element. The pair of electrodes extend the fiber length.
    Type: Grant
    Filed: September 24, 2013
    Date of Patent: July 2, 2019
    Assignees: Massachusetts Institute of Technology, FLIR Systems, Incorporated
    Inventors: Alexander Gumennik, Alexander Mark Stolyarov, Brent Richard Schell, Chong Hou, Guillaume Romain Lestoquoy, Fabien Sorin, William Richard McDaniel, II, Yoel Fink, Aimee Rose, John Dimitris Joannopoulos
  • Patent number: 9005524
    Abstract: The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: April 14, 2015
    Assignee: Nomadics, Inc.
    Inventors: Robert Deans, Aimee Rose, Kevin M. Bardon, Lawrence F. Hancock, Timothy M. Swager
  • Publication number: 20140212084
    Abstract: There is provided a sensor fiber including an electrically insulating material having a fiber length. At least one transduction element is disposed along at least a portion of the fiber length and is arranged for exposure to an intake species. A photoconducting element is in optical communication with the transduction element. At least one pair of electrically conducting electrodes are in electrical connection with the photoconducting element. The pair of electrodes extend the fiber length.
    Type: Application
    Filed: September 24, 2013
    Publication date: July 31, 2014
    Applicants: FLIR Systems, Incorporated, Massachusetts Institute of Technology
    Inventors: Alexander Gumennik, Alexander Mark Stolyarov, Brent Richard Schell, Chong Hou, Guillaume Romain Lestoquoy, Fabien Sorin, William Richard McDaniel, II, Yoel Fink, Aimee Rose, John Dimitris Joannopoulos
  • Patent number: 8647579
    Abstract: The current invention provides a detector and method suitable for sensing vapor-phase hydrogen peroxide. The detector utilizes a chemiluminescent material comprising a peroxide reactive compound, a dye and a solvent. Upon reaction with hydrogen peroxide, the chemiluminescent material will generate detectible light.
    Type: Grant
    Filed: August 24, 2007
    Date of Patent: February 11, 2014
    Assignee: Nomadics, Inc.
    Inventors: Marcus La Grone, Brian Dwayne O'Dell, Robert Deans, Aimee Rose
  • Publication number: 20140017803
    Abstract: Embodiments described herein provide materials, devices, and methods relating to the determination of analytes such as drugs, toxins, explosives, other controlled substances and contraband materials, and the like. In some embodiments, the analyte may be detected in vapor phase. Some embodiments may allow for highly sensitive and essentially instantaneous detection of analytes including drugs.
    Type: Application
    Filed: March 28, 2011
    Publication date: January 16, 2014
    Applicant: FLIR Systems, Inc.
    Inventors: Robert Deans, Aimee Rose, William McDaniel, Aaron Thompson, Steven Shaull
  • Patent number: 8298830
    Abstract: The present invention generally relates to polymers with lasing characteristics that allow the polymers to be useful in detecting analytes. In one aspect, the polymer, upon an interaction with an analyte, may exhibit a change in a lasing characteristic that can be determined in some fashion. For example, interaction of an analyte with the polymer may affect the ability of the polymer to reach an excited state that allows stimulated emission of photons to occur, which may be determined, thereby determining the analyte. In another aspect, the polymer, upon interaction with an analyte, may exhibit a change in stimulated emission that is at least 10 times greater with respect to a change in the spontaneous emission of the polymer upon interaction with the analyte. The polymer may be a conjugated polymer in some cases. In one set of embodiments, the polymer includes one or more hydrocarbon side chains, which may be parallel to the polymer backbone in some instances.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: October 30, 2012
    Assignee: Massachusetts Institute of Technology
    Inventors: Aimee Rose, Timothy M. Swager, Zhengguo Zhu, Vladimir Bulovic, Conor Francis Madigan
  • Publication number: 20120107946
    Abstract: The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.
    Type: Application
    Filed: July 9, 2010
    Publication date: May 3, 2012
    Applicant: Nomadics, Inc.
    Inventors: Robert Deans, Aimee Rose, Kevin M. Bardon, Lawrence F. Hancock, Timothy M. Swager
  • Publication number: 20100310424
    Abstract: The present invention generally relates to polymers with lasing characteristics that allow the polymers to be useful in detecting analytes. In one aspect, the polymer, upon an interaction with an analyte, may exhibit a change in a lasing characteristic that can be determined in some fashion. For example, interaction of an analyte with the polymer may affect the ability of the polymer to reach an excited state that allows stimulated emission of photons to occur, which may be determined, thereby determining the analyte. In another aspect, the polymer, upon interaction with an analyte, may exhibit a change in stimulated emission that is at least 10 times greater with respect to a change in the spontaneous emission of the polymer upon interaction with the analyte. The polymer may be a conjugated polymer in some cases. In one set of embodiments, the polymer includes one or more hydrocarbon side chains, which may be parallel to the polymer backbone in some instances.
    Type: Application
    Filed: June 7, 2010
    Publication date: December 9, 2010
    Applicant: Massachusetts Institute of Technology
    Inventors: Aimee Rose, Timothy M. Swager, Zhengguo Zhu, Vladimir Bulovic, Conor F. Madigan
  • Patent number: 7799573
    Abstract: The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.
    Type: Grant
    Filed: April 5, 2007
    Date of Patent: September 21, 2010
    Assignee: Normadics, Inc.
    Inventors: Robert Deans, Aimee Rose, Kevin M. Bardon, Lawrence F. Hancock, Timothy M. Swager
  • Patent number: 7759127
    Abstract: The present invention generally relates to polymers with lasing characteristics that allow the polymers to be useful in detecting analytes. In one aspect, the polymer, upon an interaction with an analyte, may exhibit a change in a lasing characteristic that can be determined in some fashion. For example, interaction of an analyte with the polymer may affect the ability of the polymer to reach an excited state that allows stimulated emission of photons to occur, which may be determined, thereby determining the analyte. In another aspect, the polymer, upon interaction with an analyte, may exhibit a change in stimulated emission that is at least 10 times greater with respect to a change in the spontaneous emission of the polymer upon interaction with the analyte. The polymer may be a conjugated polymer in some cases. In one set of embodiments, the polymer includes one or more hydrocarbon side chains, which may be parallel to the polymer backbone in some instances.
    Type: Grant
    Filed: December 6, 2004
    Date of Patent: July 20, 2010
    Assignee: Massachusetts Institute of Technology
    Inventors: Aimee Rose, Timothy M. Swager, Zhengguo Zhu, Vladimir Bulovic, Conor F. Madigan
  • Publication number: 20080248578
    Abstract: The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.
    Type: Application
    Filed: April 5, 2007
    Publication date: October 9, 2008
    Applicant: Nomadics, Inc.
    Inventors: Robert Deans, Aimee Rose, Kevin M. Bardon, Lawrence F. Hancock, Timothy M. Swager
  • Publication number: 20070111321
    Abstract: The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.
    Type: Application
    Filed: August 31, 2006
    Publication date: May 17, 2007
    Applicant: Nomadics, Inc.
    Inventors: Robert Deans, Aimee Rose, Marcus Grone
  • Publication number: 20060073607
    Abstract: The present invention generally relates to polymers with lasing characteristics that allow the polymers to be useful in detecting analytes. In one aspect, the polymer, upon an interaction with an analyte, may exhibit a change in a lasing characteristic that can be determined in some fashion. For example, interaction of an analyte with the polymer may affect the ability of the polymer to reach an excited state that allows stimulated emission of photons to occur, which may be determined, thereby determining the analyte. In another aspect, the polymer, upon interaction with an analyte, may exhibit a change in stimulated emission that is at least 10 times greater with respect to a change in the spontaneous emission of the polymer upon interaction with the analyte. The polymer may be a conjugated polymer in some cases. In one set of embodiments, the polymer includes one or more hydrocarbon side chains, which may be parallel to the polymer backbone in some instances.
    Type: Application
    Filed: December 6, 2004
    Publication date: April 6, 2006
    Applicant: Massachusetts Institute of Technology
    Inventors: Aimee Rose, Timothy Swager, Zhengguo Zhu, Vladimir Bulovic, Conor Madigan