Patents by Inventor Aimee Rose
Aimee Rose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230167497Abstract: Methods of identifying agents that modulate the interleukin-17 (IL-17) pathway are described. Said methods use detecting a level of granulocyte colony-stimulating factor (G-CSF) in a cell supernatant and/or detecting an expression level of one gene or a panel of genes of a cell treated with an agent. Also described are probes capable of detecting a gene or panel of genes and kits for identifying agents that modulate the IL-17 pathway.Type: ApplicationFiled: April 28, 2021Publication date: June 1, 2023Inventors: Katherine Y. Blain, Aimee Rose de Leon-Tabaldo, Anne M. Fourie, Steven Goldberg, Xuejun Liu, Rosa Luna-Roman, Michael Angelo Rodriguez, Xiaohua Xue
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Publication number: 20220365100Abstract: Methods to measure total IL-17 in a biological sample comprising the IL-17 and a large molecule modulator of IL-17.Type: ApplicationFiled: September 28, 2020Publication date: November 17, 2022Inventors: Jonathan M. BLEVITT, Aimee Rose DE LEON-TABALDO, Wai-Ping LEUNG, Xiaohua XUE
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Publication number: 20220357341Abstract: Methods to measure free IL-17 in a sample comprising IL-17 and a small molecule modulator of IL-17.Type: ApplicationFiled: September 28, 2020Publication date: November 10, 2022Inventors: Jonathan M. BLEVITT, Aimee Rose DE LEON-TABALDO, Samuel E. DEPRIMO, Steven GOLDBERG, Wai-Ping LEUNG, Amy STRASNER, Xiaohua XUE
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Patent number: 10338000Abstract: There is provided a sensor fiber including an electrically insulating material having a fiber length. At least one transduction element is disposed along at least a portion of the fiber length and is arranged for exposure to an intake species. A photoconducting element is in optical communication with the transduction element. At least one pair of electrically conducting electrodes are in electrical connection with the photoconducting element. The pair of electrodes extend the fiber length.Type: GrantFiled: September 24, 2013Date of Patent: July 2, 2019Assignees: Massachusetts Institute of Technology, FLIR Systems, IncorporatedInventors: Alexander Gumennik, Alexander Mark Stolyarov, Brent Richard Schell, Chong Hou, Guillaume Romain Lestoquoy, Fabien Sorin, William Richard McDaniel, II, Yoel Fink, Aimee Rose, John Dimitris Joannopoulos
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Patent number: 9005524Abstract: The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.Type: GrantFiled: July 9, 2010Date of Patent: April 14, 2015Assignee: Nomadics, Inc.Inventors: Robert Deans, Aimee Rose, Kevin M. Bardon, Lawrence F. Hancock, Timothy M. Swager
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Publication number: 20140212084Abstract: There is provided a sensor fiber including an electrically insulating material having a fiber length. At least one transduction element is disposed along at least a portion of the fiber length and is arranged for exposure to an intake species. A photoconducting element is in optical communication with the transduction element. At least one pair of electrically conducting electrodes are in electrical connection with the photoconducting element. The pair of electrodes extend the fiber length.Type: ApplicationFiled: September 24, 2013Publication date: July 31, 2014Applicants: FLIR Systems, Incorporated, Massachusetts Institute of TechnologyInventors: Alexander Gumennik, Alexander Mark Stolyarov, Brent Richard Schell, Chong Hou, Guillaume Romain Lestoquoy, Fabien Sorin, William Richard McDaniel, II, Yoel Fink, Aimee Rose, John Dimitris Joannopoulos
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Patent number: 8647579Abstract: The current invention provides a detector and method suitable for sensing vapor-phase hydrogen peroxide. The detector utilizes a chemiluminescent material comprising a peroxide reactive compound, a dye and a solvent. Upon reaction with hydrogen peroxide, the chemiluminescent material will generate detectible light.Type: GrantFiled: August 24, 2007Date of Patent: February 11, 2014Assignee: Nomadics, Inc.Inventors: Marcus La Grone, Brian Dwayne O'Dell, Robert Deans, Aimee Rose
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Publication number: 20140017803Abstract: Embodiments described herein provide materials, devices, and methods relating to the determination of analytes such as drugs, toxins, explosives, other controlled substances and contraband materials, and the like. In some embodiments, the analyte may be detected in vapor phase. Some embodiments may allow for highly sensitive and essentially instantaneous detection of analytes including drugs.Type: ApplicationFiled: March 28, 2011Publication date: January 16, 2014Applicant: FLIR Systems, Inc.Inventors: Robert Deans, Aimee Rose, William McDaniel, Aaron Thompson, Steven Shaull
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Patent number: 8298830Abstract: The present invention generally relates to polymers with lasing characteristics that allow the polymers to be useful in detecting analytes. In one aspect, the polymer, upon an interaction with an analyte, may exhibit a change in a lasing characteristic that can be determined in some fashion. For example, interaction of an analyte with the polymer may affect the ability of the polymer to reach an excited state that allows stimulated emission of photons to occur, which may be determined, thereby determining the analyte. In another aspect, the polymer, upon interaction with an analyte, may exhibit a change in stimulated emission that is at least 10 times greater with respect to a change in the spontaneous emission of the polymer upon interaction with the analyte. The polymer may be a conjugated polymer in some cases. In one set of embodiments, the polymer includes one or more hydrocarbon side chains, which may be parallel to the polymer backbone in some instances.Type: GrantFiled: June 7, 2010Date of Patent: October 30, 2012Assignee: Massachusetts Institute of TechnologyInventors: Aimee Rose, Timothy M. Swager, Zhengguo Zhu, Vladimir Bulovic, Conor Francis Madigan
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Publication number: 20120107946Abstract: The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.Type: ApplicationFiled: July 9, 2010Publication date: May 3, 2012Applicant: Nomadics, Inc.Inventors: Robert Deans, Aimee Rose, Kevin M. Bardon, Lawrence F. Hancock, Timothy M. Swager
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Publication number: 20100310424Abstract: The present invention generally relates to polymers with lasing characteristics that allow the polymers to be useful in detecting analytes. In one aspect, the polymer, upon an interaction with an analyte, may exhibit a change in a lasing characteristic that can be determined in some fashion. For example, interaction of an analyte with the polymer may affect the ability of the polymer to reach an excited state that allows stimulated emission of photons to occur, which may be determined, thereby determining the analyte. In another aspect, the polymer, upon interaction with an analyte, may exhibit a change in stimulated emission that is at least 10 times greater with respect to a change in the spontaneous emission of the polymer upon interaction with the analyte. The polymer may be a conjugated polymer in some cases. In one set of embodiments, the polymer includes one or more hydrocarbon side chains, which may be parallel to the polymer backbone in some instances.Type: ApplicationFiled: June 7, 2010Publication date: December 9, 2010Applicant: Massachusetts Institute of TechnologyInventors: Aimee Rose, Timothy M. Swager, Zhengguo Zhu, Vladimir Bulovic, Conor F. Madigan
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Patent number: 7799573Abstract: The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.Type: GrantFiled: April 5, 2007Date of Patent: September 21, 2010Assignee: Normadics, Inc.Inventors: Robert Deans, Aimee Rose, Kevin M. Bardon, Lawrence F. Hancock, Timothy M. Swager
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Patent number: 7759127Abstract: The present invention generally relates to polymers with lasing characteristics that allow the polymers to be useful in detecting analytes. In one aspect, the polymer, upon an interaction with an analyte, may exhibit a change in a lasing characteristic that can be determined in some fashion. For example, interaction of an analyte with the polymer may affect the ability of the polymer to reach an excited state that allows stimulated emission of photons to occur, which may be determined, thereby determining the analyte. In another aspect, the polymer, upon interaction with an analyte, may exhibit a change in stimulated emission that is at least 10 times greater with respect to a change in the spontaneous emission of the polymer upon interaction with the analyte. The polymer may be a conjugated polymer in some cases. In one set of embodiments, the polymer includes one or more hydrocarbon side chains, which may be parallel to the polymer backbone in some instances.Type: GrantFiled: December 6, 2004Date of Patent: July 20, 2010Assignee: Massachusetts Institute of TechnologyInventors: Aimee Rose, Timothy M. Swager, Zhengguo Zhu, Vladimir Bulovic, Conor F. Madigan
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Publication number: 20080248578Abstract: The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.Type: ApplicationFiled: April 5, 2007Publication date: October 9, 2008Applicant: Nomadics, Inc.Inventors: Robert Deans, Aimee Rose, Kevin M. Bardon, Lawrence F. Hancock, Timothy M. Swager
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Publication number: 20070111321Abstract: The present invention provides a series of systems, devices, and methods relating to the determination of explosives, such as peroxides or peroxide precursors, and other species. Embodiments of the invention may allow a sample suspected of containing an explosive (e.g., a peroxide) or other species to interact with a reactant, wherein the sample may react and cause light emission from the reactant. Advantages of the present invention may include the simplification of devices for determination of peroxide-based explosives, wherein the devices are portable and, in some cases, disposable. Other advantages may include relative ease of fabrication and operation.Type: ApplicationFiled: August 31, 2006Publication date: May 17, 2007Applicant: Nomadics, Inc.Inventors: Robert Deans, Aimee Rose, Marcus Grone
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Publication number: 20060073607Abstract: The present invention generally relates to polymers with lasing characteristics that allow the polymers to be useful in detecting analytes. In one aspect, the polymer, upon an interaction with an analyte, may exhibit a change in a lasing characteristic that can be determined in some fashion. For example, interaction of an analyte with the polymer may affect the ability of the polymer to reach an excited state that allows stimulated emission of photons to occur, which may be determined, thereby determining the analyte. In another aspect, the polymer, upon interaction with an analyte, may exhibit a change in stimulated emission that is at least 10 times greater with respect to a change in the spontaneous emission of the polymer upon interaction with the analyte. The polymer may be a conjugated polymer in some cases. In one set of embodiments, the polymer includes one or more hydrocarbon side chains, which may be parallel to the polymer backbone in some instances.Type: ApplicationFiled: December 6, 2004Publication date: April 6, 2006Applicant: Massachusetts Institute of TechnologyInventors: Aimee Rose, Timothy Swager, Zhengguo Zhu, Vladimir Bulovic, Conor Madigan