Patents by Inventor Aimei Yang

Aimei Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Step-function channelrhodopsins for optical control of cells
    Patent number: 11542314
    Abstract: The invention, in some aspects relates to light-activated ion channel molecules and methods for their use to alter cell activity and function. Light-activated ion channel molecules of the invention can be administered to subjects, expressed in cells, and activated with light, to alter membrane potential in the cells, and can be used in methods for assaying compounds, treating diseases and conditions, compound screening and more.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: January 3, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: Aimei Yang, Demian Park, Edward S. Boyden
  • Dummy-fluorescent protein fusions and methods of use
    Patent number: 11278633
    Abstract: The invention, in some aspects, relates to dummy-fluorescent (DF) polypeptide molecules and their encoding nucleic acid molecules and use of such molecules in fusion proteins and their encoding nucleic acid molecules. Compositions of the invention may be delivered to cells and subjects and used in methods to modulate electrical activity of cells in which they are expressed, and for treatment of diseases and conditions in subjects.
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: March 22, 2022
    Assignee: Massachusetts Institute of Technology
    Inventors: Aimei Yang, Demian Park, Kiryl Piatkevich, Edward Boyden
  • DUMMY-FLUORESCENT PROTEIN FUSIONS AND METHODS OF USE
    Publication number: 20190290786
    Abstract: The invention, in some aspects, relates to dummy-fluorescent (DF) polypeptide molecules and their encoding nucleic acid molecules and use of such molecules in fusion proteins and their encoding nucleic acid molecules. Compositions of the invention may be delivered to cells and subjects and used in methods to modulate electrical activity of cells in which they are expressed, and for treatment of diseases and conditions in subjects.
    Type: Application
    Filed: July 20, 2017
    Publication date: September 26, 2019
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Aimei YANG, Demian PARK, Kiryl PIATKEVICH, Edward BOYDEN
  • STEP-FUNCTION CHANNELRHODOPSINS FOR OPTICAL CONTROL OF CELLS
    Publication number: 20190079074
    Abstract: The invention, in some aspects relates to light-activated ion channel molecules and methods for their use to alter cell activity and function. Light-activated ion channel molecules of the invention can be administered to subjects, expressed in cells, and activated with light, to alter membrane potential in the cells, and can be used in methods for assaying compounds, treating diseases and conditions, compound screening and more.
    Type: Application
    Filed: September 10, 2018
    Publication date: March 14, 2019
    Inventors: Aimei Yang, Demian Park, Edward S. Boyden