Patents by Inventor Aimin Zhang

Aimin Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9187459
    Abstract: The invention provides quinazoline-7-ether derivatives, particularly 4-anilinyl-6-butenamido-quinazoline-7-ether derivatives that are inhibitors of the receptor protein tyrosine kinases (RTK). The compounds are useful in the treatment of diseases and disorders where RTK activity is implicated such as a hyperproliferative diseases (e.g., cancer). Also provided are methods of preparation of the quinazoline derivatives and methods of use as therapeutic agents alone or in a drug combination.
    Type: Grant
    Filed: May 17, 2012
    Date of Patent: November 17, 2015
    Assignee: NewGen Therapeutics, Inc.
    Inventors: Wang Shen, Wei Xiao, Jack Maung, Aimin Zhang, Xiaoling Zheng, Zhenzhong Wang, Qingming Guo, Yingguang Li
  • Patent number: 9090588
    Abstract: The invention provides alkyne substituted quinazoline compounds, such as compounds of the formula (I), which are irreversible ErbB kinase inhibitors. The compounds are useful in the treatment of diseases and disorders where ErbB kinase activity is implicated such as a hyperproliferative disorder (e.g., cancer).
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: July 28, 2015
    Assignee: NewGen Therapeutics, Inc.
    Inventors: Wang Shen, Aimin Zhang, Jack Maung, Xiaoling Zheng
  • Patent number: 8987284
    Abstract: Disclosed are novel quinazoline derivatives containing phosphorus substitutions and methods for the treatment of hyperproliferative diseases (e.g. cancer) using the compounds. These compounds are type I receptor protein kinase inhibitors useful in treating disorders related to abnormal protein kinase activities such as cancer and inflammation in mammals. Also disclosed are pharmaceutical compositions containing the compounds, methods for the preparation of the compounds and their pharmaceutically acceptable salts.
    Type: Grant
    Filed: July 2, 2010
    Date of Patent: March 24, 2015
    Assignee: Newgen Therapeutics, Inc.
    Inventors: Wang Shen, Aimin Zhang, Junfa Fan, Xiaoling Zheng
  • Publication number: 20150051309
    Abstract: A styrenic monomer-diolefin copolymer comprises polystyrenic monomer micro-blocks and polydiolefin micro-blocks, in which the content of styrenic monomer units is 10-80 wt %, the ratio of diolefin units of 1,2-structure is less than 30% in the total diolefin units, and the number-average molecular weight (Mn) of the copolymer is 25,000-500,000. The preparation methods and uses in foam products thereof are also disclosed.
    Type: Application
    Filed: January 16, 2014
    Publication date: February 19, 2015
    Inventors: Hongwen Liang, Aimin Zhang, Lixin Zhou, Jinkl Xia, Zhibin Zhang, Weiping Zhou
  • Publication number: 20140221406
    Abstract: The invention provides quinazoline-7-ether derivatives, particularly 4-anilinyl-6-butenamido-quinazoline-7-ether derivatives that are inhibitors of the receptor protein tyrosine kinases (RTK). The compounds are useful in the treatment of diseases and disorders where RTK activity is implicated such as a hyperproliferative diseases (e.g., cancer). Also provided are methods of preparation of the quinazoline derivatives and methods of use as therapeutic agents alone or in a drug combination.
    Type: Application
    Filed: May 17, 2012
    Publication date: August 7, 2014
    Applicant: Newgen Therapeutics, Inc.
    Inventors: Wang Shen, Wei Xiao, Jack Maung, Aimin Zhang, Xiaoling Zheng, Zhenzhong Wang, Qingming Guo, Yingguang Li
  • Publication number: 20140221314
    Abstract: The invention provides for compositions comprising phosphorous containing tricyclic compounds, including phthalazin-1(2H)-one derivatives. The compounds are potent inhibitors of the enzyme poly(ADP-ribose)polymerase (PARP), particularly PARP-1 and potentially PARP-2. The also show good cellular activity in inhibiting poly(ADP-ribose) oligomer formation. The compounds may be useful as mono-therapy or in combination with other therapeutic agents in the treatment conditions where PARP is implicated, such as cancer, inflammatory diseases and ischemic conditions. Thus, also provided are methods for the treatment of a condition where PARP is implicated comprising administering to an effective amount of a compound of the invention to an individual in need thereof.
    Type: Application
    Filed: May 31, 2012
    Publication date: August 7, 2014
    Applicant: NewGen Therapeutics, Inc.
    Inventors: Wang Shen, Jack Maung, Aimin Zhang, Xiaoling Zheng
  • Publication number: 20140128417
    Abstract: The invention provides alkyne substituted quinazoline compounds, such as compounds of the formula (I), which are irreversible ErbB kinase inhibitors. The compounds are useful in the treatment of diseases and disorders where ErbB kinase activity is implicated such as a hyperproliferative disorder (e.g., cancer).
    Type: Application
    Filed: March 2, 2012
    Publication date: May 8, 2014
    Applicant: Newgen Therapeutics, Inc.
    Inventors: Wang Shen, Aimin Zhang, Jack Maung, Xiaoling Zheng
  • Patent number: 8305982
    Abstract: A method for assigning signature sequences for E-HICH channel which may avoid the unbalanced situation brought about by the codeword assignment is provided, wherein the use of User Equipment (UE) signature sequences on Enhanced Dedicated Channel Hybrid Automatic Repeat Request Acknowledgement Indicator Channel (E-HICH) is equalized, so as to drive the average detection performance toward equity for different UEs to detect their respective signature sequences on E-HICH channel, and to reduce the average false detection rate for the respective UE on the feedback information transmitted thereto. The method includes: firstly, assigning a E-HICH logical signature sequence index r for each UE; then, converting the logical signature sequence index r into a physical signature sequence index r? varying with time by using a random permutation function; and after that, assigning a signature sequence corresponding to the physical signature sequence index r? to the respective UE.
    Type: Grant
    Filed: October 23, 2009
    Date of Patent: November 6, 2012
    Assignee: Spreadtrum Communications (Shanghai) Co. Ltd.
    Inventors: Aimin Zhang, Zhiqun Chen, Yanshan Shi
  • Patent number: 8244259
    Abstract: A method for relay stations (RSs) to forward downlink signals includes: obtaining downlink qualities between a mobile station (MS) and each of the RSs; determining an RS group for forwarding downlink signals according to difference degrees among all of the downlink qualities; performing space-time coding on the downlink signals through the RSs in the RS group when the RS group contains a plurality of RSs. Another method for RSs to forward downlink signals includes: setting the number of the RSs for forwarding the downlink signals to plurality; obtaining downlink qualities between an MS and each of the RSs; determining an RS group for forwarding the downlink signals according to each of the downlink qualities and the number of the RSs; performing space-time coding on the downlink signals through the RSs in the RS group, and forwarding the downlink signals to the MS. A device structure for the RSs to forward the downlink signals is also provided.
    Type: Grant
    Filed: July 11, 2008
    Date of Patent: August 14, 2012
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Shiqiang Deng, Aimin Zhang
  • Publication number: 20120196833
    Abstract: Disclosed are novel quinazoline derivatives containing phosphorus substitutions and methods for the treatment of hyperproliferative diseases (e.g. cancer) using the compounds. These compounds are type I receptor protein kinase inhibitors useful in treating disorders related to abnormal protein kinase activities such as cancer and inflammation in mammals. Also disclosed are pharmaceutical compositions containing the compounds, methods for the preparation of the compounds and their pharmaceutically acceptable salts.
    Type: Application
    Filed: July 2, 2010
    Publication date: August 2, 2012
    Inventors: Wang Shen, Aimin Zhang, Junfa Fan, Xiaoling Zheng
  • Patent number: 8086173
    Abstract: A method for implementing a random access of a new access node and a system thereof are provided, which belong to a wireless communication field, and enable the new access node within the coverage of relay stations to implement the random access. In the application, when the new access node is located within the coverage of the relay stations, each of the relay stations notifies an access request sent from the new access node to a synchronization station via a report message, and the synchronization station compares the access request forwarded by each of the relay stations and the access request received by itself from the same new access node, selects a station with the best signal quality of the received access request, and implements the access of the new access node in accordance with the types of selected station and the synchronization station itself.
    Type: Grant
    Filed: March 13, 2009
    Date of Patent: December 27, 2011
    Assignee: Huawei Technologies Co., Ltd.
    Inventors: Aimin Zhang, Yanling Lu, Jiang Li, Shulan Feng, Zheng Shang
  • Publication number: 20110204536
    Abstract: A styrenic monomer-diolefin copolymer comprises polystyrenic monomer micro-blocks and polydiolefin micro-blocks, in which the content of styrenic monomer units is 10-80 wt %, the ratio of diolefin units of 1,2-structure is less than 30% in the total diolefin units, and the number-average molecular weight (Mn) of the copolymer is 25,000-500,000. The preparation methods and uses in foam products thereof are also disclosed.
    Type: Application
    Filed: July 15, 2009
    Publication date: August 25, 2011
    Inventors: Hongwen Liang, Aimin Zhang, Lixin Zhou, Jinkui Xia, Zhibin Zhang, Weiping Zhou
  • Publication number: 20100220672
    Abstract: The present disclosure discloses a method for assigning signature sequences for E-HICH channel which may avoid the unbalanced situation brought about by the codeword assignment, wherein the use of UE signature sequences on E-HICH channel is equalized, so as to drive the average detection performance toward equity for different UEs to detect their respective signature sequences on E-HICH channel, and to reduce the average false detection rate for the respective UE on the feedback information transmitted thereto. The method comprises: firstly, assigning a E-HICH logical signature sequence index r for each UE; then, converting the logical signature sequence index r into a physical signature sequence index r? varying with time by using a random permutation function; and after that, assigning a signature sequence corresponding to the physical signature sequence index r? to the respective UE.
    Type: Application
    Filed: October 23, 2009
    Publication date: September 2, 2010
    Inventors: Aimin Zhang, Zhiqun Chen, Yanshan Shi
  • Publication number: 20090221288
    Abstract: A method for implementing a random access of a new access node and a system thereof are provided, which belong to a wireless communication field, and enable the new access node within the coverage of relay stations to implement the random access. In the application, when the new access node is located within the coverage of the relay stations, each of the relay stations notifies an access request sent from the new access node to a synchronization station via a report message, and the synchronization station compares the access request forwarded by each of the relay stations and the access request received by itself from the same new access node, selects a station with the best signal quality of the received access request, and implements the access of the new access node in accordance with the types of selected station and the synchronization station itself.
    Type: Application
    Filed: March 13, 2009
    Publication date: September 3, 2009
    Applicant: Huawei Technologies Co., Ltd.
    Inventors: Aimin Zhang, Yanling Lu, Jiang Li, Shulan Feng, Zheng Shang
  • Publication number: 20090213779
    Abstract: A downlink data transmitting method is applied to a multi-hop wireless relay communication system. The method includes the following steps. A network unit obtains an identifier of a next hop network unit corresponding to a connection identifier (CID) in a downlink medium access control protocol data unit (MPDU) header according to an existing corresponding relationship of the CID and a path ID, and sends the downlink MPDU to the next hop network unit by utilizing the obtained identifier of the next hop network unit, so that a data transmission of multi-hop wireless communication system is realized without changing a current user terminal and protocol structure of a core network. Meanwhile, a multi-hop wireless relay system, and a base station and relay stations applied to the system are described.
    Type: Application
    Filed: March 17, 2009
    Publication date: August 27, 2009
    Inventors: Aimin ZHANG, Zheng SHANG, Chengyan FENG, Jiang LI
  • Publication number: 20090217119
    Abstract: A method for implementing hybrid automatic retransmission is provided in a communication system. In the method, a terminal transmits a data block to a receiving side through a relay station; the relay station returns a receiving status of the relay station to the receiving side; and the transmitting side determines whether retransmission of the data block is needed according to the receiving status. A system for implementing hybrid automatic retransmission and a relay station are described, also. Accordingly, the system performance is enhanced, the transmission quality is improved. In addition, the relay station is transparent to the terminal such that no modification is required to be made to the existing terminal in the system having a relay station.
    Type: Application
    Filed: December 22, 2008
    Publication date: August 27, 2009
    Applicant: Huawei Technologies Co., Ltd.
    Inventors: Aimin ZHANG, Zheng SHANG, Yuanyuan WANG
  • Publication number: 20090073915
    Abstract: An apparatus, system and method for implementing mobile communication are described. The apparatus includes: a transmitter, a receiver, a duplexer, and an antenna. The apparatus further includes: an uplink data processing module, configured to process data transmitted from a terminal to a base station and received by the receiver, and transmit the processed data to the transmitter; a downlink data processing module, configured to process data transmitted from a base station to a terminal and received by the receiver, and transmit the processed data to the transmitter, the downlink data processing module sharing the transmitter and the receiver with the uplink data processing module in a time-division manner; and a control processor, configured to control the transmitter, the receiver, the uplink data processing module, and the downlink data processing module.
    Type: Application
    Filed: October 27, 2008
    Publication date: March 19, 2009
    Applicant: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Aimin ZHANG, Jiang LI, Shiqiang DENG
  • Publication number: 20080285502
    Abstract: A method for relay stations (RSs) to forward downlink signals includes: obtaining downlink qualities between a mobile station (MS) and each of the RSs; determining an RS group for forwarding downlink signals according to difference degrees among all of the downlink qualities; performing space-time coding on the downlink signals through the RSs in the RS group when the RS group contains a plurality of RSs. Another method for RSs to forward downlink signals includes: setting the number of the RSs for forwarding the downlink signals to plurality; obtaining downlink qualities between an MS and each of the RSs; determining an RS group for forwarding the downlink signals according to each of the downlink qualities and the number of the RSs; performing space-time coding on the downlink signals through the RSs in the RS group, and forwarding the downlink signals to the MS. A device structure for the RSs to forward the downlink signals is also provided.
    Type: Application
    Filed: July 11, 2008
    Publication date: November 20, 2008
    Applicant: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Shiqiang DENG, Aimin ZHANG
  • Patent number: 6351951
    Abstract: A thermoelectric cooling device using heat pipes for heat conducting and dispersing, comprising a multi-bundle of the heat pipe conducting plates installed at the cold end of the thermoelectric cooling member and converged to condenser, a multi-bundle of the heat pipe heat exchangers installed at the hot end of the thermoelectric cooling member with fin plates or fin stripes and converged to the evaporator. It performs a fast cooling and heat dispersing by heat pipes and high efficient phase change and heat transport of the working medium. It can eliminate the heat exchange produced by the heat accumulation on the cold and hot ends, so as to run at the minimum operation temperature differences in order to obtain the maximum cooling capacity.
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: March 5, 2002
    Inventors: Chen Guo, Junling Gao, Aimin Zhang