Patents by Inventor Aina He

Aina He has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanocrystalline soft magnetic alloy with high magnetic induction and high frequency and preparation method thereof
    Patent number: 12646642
    Abstract: Disclosed in the present invention is a nanocrystalline soft magnetic alloy with high magnetic induction and high frequency. The nanocrystalline soft magnetic alloy has a molecular formula of FeaSibBcMadCuePf, in which M includes one or more of Nb, Mo, V, Mn, and Cr, molar percent contents of elements are as follows: 6?b?15, 5?c?12, 0.5?d?3, 0.5?e?1.5, and 0.5?f?3, and the balance includes Fe and impurities. A difference between an induced anisotropy value and an average magnetocrystalline anisotropy value is 0.1-1 J/m3. The soft magnetic alloy has high magnetic permeability and low magnetic loss at high frequency. Further disclosed in the present disclosure is a method for preparing the nanocrystalline soft magnetic alloy with high magnetic induction and high frequency.
    Type: Grant
    Filed: July 1, 2022
    Date of Patent: June 2, 2026
    Assignee: NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING CHINESE ACADEMY OF SCIENCES
    Inventors: Jiawei Li, Yu Sun, Aina He, Yaqiang Dong
  • Compositions and methods for inhibiting Wnt signaling
    Patent number: 12252515
    Abstract: Provided herein are agents that bind to the lipid binding groove of Frizzled (FZD). In some embodiments, the agent is a fragment of TcdB corresponding to amino acids 1285-1804 of SEQ ID NO: 1. In some embodiments, binding of the agent to the lipid binding groove of FZD inhibits TcdB entry into cells, and/or inhibits Wnt signaling. Methods of treating Clostridium difficile infection (CDI) and methods of treating cancer are also provided.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: March 18, 2025
    Assignees: Children's Medical Center Corporation, The Regents of the University of California
    Inventors: Min Dong, Liang Tao, Rongsheng Jin, Peng Chen, Aina He
  • NANOCRYSTALLINE SOFT MAGNETIC ALLOY WITH HIGH MAGNETIC INDUCTION AND HIGH FREQUENCY AND PREPARATION METHOD THEREOF
    Publication number: 20240258001
    Abstract: Disclosed in the present invention is a nanocrystalline soft magnetic alloy with high magnetic induction and high frequency. The nanocrystalline soft magnetic alloy has a molecular formula of FeaSibBcMadCuePf, in which M includes one or more of Nb, Mo, V, Mn, and Cr, molar percent contents of elements are as follows: 6?b?15, 5?c?12, 0.5?d?3, 0.5?e?1.5, and 0.5?f?3, and the balance includes Fe and impurities. A difference between an induced anisotropy value and an average magnetocrystalline anisotropy value is 0.1-1 J/m3. The soft magnetic alloy has high magnetic permeability and low magnetic loss at high frequency. Further disclosed in the present disclosure is a method for preparing the nanocrystalline soft magnetic alloy with high magnetic induction and high frequency.
    Type: Application
    Filed: July 1, 2022
    Publication date: August 1, 2024
    Inventors: JIAWEI LI, YU SUN, AINA HE, YAQIANG DONG
  • COMPOSITIONS AND METHODS FOR INHIBITING WNT SIGNALING
    Publication number: 20200339636
    Abstract: Provided herein are agents that bind to the lipid binding groove of Frizzled (FZD). In some embodiments, the agent is a fragment of TcdB corresponding to amino acids 1285-1804 of SEQ ID NO: 1. In some embodiments, binding of the agent to the lipid binding groove of FZD inhibits TcdB entry into cells, and/or inhibits Wnt signaling. Methods of treating Clostridium difficile infection (CDI) and methods of treating cancer are also provided.
    Type: Application
    Filed: January 14, 2019
    Publication date: October 29, 2020
    Applicants: Children's Medical Center Corporation, The Regents of the University of California
    Inventors: Min Dong, Liang Tao, Rongsheng Jin, Peng Chen, Aina He