Patents by Inventor Aina He

Aina He has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR INHIBITING WNT SIGNALING
    Publication number: 20200339636
    Abstract: Provided herein are agents that bind to the lipid binding groove of Frizzled (FZD). In some embodiments, the agent is a fragment of TcdB corresponding to amino acids 1285-1804 of SEQ ID NO: 1. In some embodiments, binding of the agent to the lipid binding groove of FZD inhibits TcdB entry into cells, and/or inhibits Wnt signaling. Methods of treating Clostridium difficile infection (CDI) and methods of treating cancer are also provided.
    Type: Application
    Filed: January 14, 2019
    Publication date: October 29, 2020
    Applicants: Children's Medical Center Corporation, The Regents of the University of California
    Inventors: Min Dong, Liang Tao, Rongsheng Jin, Peng Chen, Aina He