Patents by Inventor Aine Blanchard

Aine Blanchard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High fidelity restriction endonucleases
    Patent number: 8372619
    Abstract: Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins. Embodiments of the method are particularly suited for modifying specific properties of restriction endonucleases such as star activity. The compositions include restriction endonucleases with reduced star activity as defined by an overall fidelity index improvement factor.
    Type: Grant
    Filed: July 14, 2008
    Date of Patent: February 12, 2013
    Assignee: New England Biolabs, Inc.
    Inventors: Zhenyu Zhu, Aine Blanchard, Shuang-Yong Xu, Shengxi Guan, Hua Wei, Penghua Zhang, Dapeng Sun, Siu-hong Chan
  • High Fidelity Restriction Endonucleases
    Publication number: 20090029376
    Abstract: Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins. Embodiments of the method are particularly suited for modifying specific properties of restriction endonucleases such as star activity. The compositions include restriction endonucleases with reduced star activity as defined by an overall fidelity index improvement factor.
    Type: Application
    Filed: July 14, 2008
    Publication date: January 29, 2009
    Applicant: New England Biolabs, Inc.
    Inventors: Zhenyu Zhu, Aine Blanchard, Shuang-Yong Xu, Shengxi Guan, Hua Wei, Penghua Zhang, Dapeng Sun, Siu-Hong Chan