Abstract: This invention relates to reticulated elastomeric matrices, their manufacture, their post-processing, such as their reinforcement, compressive molding or annealing, and uses including uses for implantable devices into or for topical treatment of patients, such as humans and other animals, for surgical devices, tissue augmentation, tissue repair, therapeutic, nutritional, or other useful purposes.

Abstract: An article comprising two or more layers. One or more of the layers includes of a polymeric foam tape containing one or more curable resins. One aspect of the present invention is to use the article as an orthopedic casting splint.

Abstract: An article including a polymeric foam having a thickness of less than about 3/16 inch (about 5 mm) and one or more curable resins.

Abstract: An orthopedic casting article comprising a polymeric foam tape containing one or more curable resins. The polymeric foam tape can be a foam having a substantially open cell structure, substantially closed cell structure, or a substantially reticulated cell structure. The curable resin can be a water-curable resin. The casting article can be multi-layered to obtain an article suitable for splinting applications.

Abstract: An activatable material and articles incorporating the same is disclosed. The activatable material includes an isocyanate and an isocyanate reactive compound. The isocyanate is typically blocked such that the activatable material is non-reactive at temperatures below about 100° C. The activatable material is preferably used for sealing, baffling, reinforcing, adhering, sound attenuation, sound damping or the like of an article of manufacture such as an automotive vehicle.

Abstract: Methods of performing medical procedures, and methods of making bone-growth-promoting compositions useful in performing medical procedures are provided. Apparatus useful both in methods of performing medical procedures, and in methods of making bone-growth-promoting compositions useful in performing medical procedures, are provided. The bone-growth-promoting compositions made according to the disclosed methods are biocompatible, and are adapted to stimulate bone growth when positioned in contact with, or in the vicinity of, a bone of a mammal.

Abstract: One aspect of the present invention is a casting article comprised of a water-curable Plaster of Paris (PP) article having a first side and a second side and having a substrate and PP material and a polyisocyanate material being applied to at least one of the first and second sides of the water-curable PP to obtain a water-curable hybrid plaster-polyisocyanate (HPP) casting article.

Abstract: This invention relates to biodurable, reticulated elastomeric matrices that are resiliently-compressible, their manufacture and uses including uses for implantable devices into or for topical treatment of patients, such as humans and other animals, for therapeutic, nutritional, or other useful purposes.

Abstract: This invention relates to biodurable, reticulated elastomeric matrices that are resiliently-compressible, their manufacture and uses including uses for implantable devices into or for topical treatment of patients, such as humans and other animals, for therapeutic, nutritional, or other useful purposes.

Abstract: The present invention provides compositions that may be useful, inter alia, in medical procedures, methods for making such compositions, and methods of performing medical procedures using such compositions. The present invention further provides a kit that includes a first container comprising a dispensing means and a first compound; and a second container comprising a dispensing means and a second compound, wherein the first compound may include, inter alia, a naturally occurring polyol, a biocompatible synthetic polyol, and mixtures thereof, and wherein the second compound may include, inter alia, isocyanate.

Abstract: An orthopedic casting article comprising a polymeric foam tape containing one or more curable resins. The polymeric foam tape can be a foam having a substantially open cell structure, substantially closed cell structure, or a substantially reticulated cell structure. The curable resin can be a water-curable resin. The casting article can be multi-layered to obtain an article suitable for splinting applications.

Abstract: This invention relates to polyurethane compounds, e.g., elastomers, which are the reaction product of a cycloaliphatic diisocyanate, a polyol and a chain extender. The cycloaliphatic diisocyanate comprises (i) trans-1,4-bis(isocyanatomethyl)cyclohexane or (ii) an isomeric mixture of two or more of cis-1,3-bis(isocyanatomethyl)cyclohexane, trans-1,3-bis(isocyanatomethyl)cyclohexane, cis-1,4-bis(isocyanatomethyl)cyclohexane and trans-1,4-bis(isocyanatomethyl)cyclohexane, provided the isomeric mixture comprises at least about 5 weight percent of said trans-1,4-bis(isocyanatomethyl)cyclohexane. This invention also relates to shaped and molded articles prepared from said polyurethane compounds.

Abstract: One aspect of the present invention is a casting article comprised of a water-curable Plaster of Paris (PP) article having a first side and a second side and having a substrate and PP material and a polyisocyanate material being applied to at least one of the first and second sides of the water-curable PP to obtain a water-curable hybrid plaster-polyisocyanate (HPP) casting article.

Abstract: Disclosed is a new class of TPUs with improved properties, based on poly(1,3-propanediol carbonate) diol, using 10 to 55% hard segment concentration, and cured with a diisocyanate. The composition provides a broader range of mechanical and thermal properties for TPU formulations, including improvements in hardness, higher elasticity modulus, and improved softening temperature and coefficient of thermal expansion, in addition to improved clarity.

Abstract: Disclosed is a new class of TPUs with improved properties, based on poly(1,3-propanediol carbonate) diol, using 10 to 550 hard segment concentration, and cured with a diisocyanate. The composition provides a broader range of mechanical and thermal properties for TPU formulations, including improvements in hardness, higher elasticity modulus, and improved softening temperature and coefficient of thermal expansion, in addition to improved clarity.

Abstract: An article of manufacture for load bearing medical use such as a joint implant suitable for total joint replacement. The article comprises a polyurethane-containing component and is monolithic with respect to polyurethane-containing component(s). The joint for long term load applications is structurally an articulated joint and the polyurethane component provides a surface for articulation with the polyurethane.

Abstract: Thermoplastic polyurethanes are formed from a hydrogenated polydiene diol having from 1.6 to 2 terminal hydroxyl groups per molecule and a number average molecular weight between 500 and 20,000, an isocyanate having two isocyanate groups per molecule, and optionally a chain extender having two hydroxyl groups per molecule. The thermoplastic polyurethanes have excellent resistance to moisture as evidenced by retention of more than 70%, preferably at least 85%, of original tensile strength after aging in water for 7 days at a temperature of at least 70.degree. C. Preparation by a prepolymer method with subsequent addition of the chain extender is preferred.

Abstract: Cast polyurethanes are preferably formed from a hydrogenated polydiene diol having from up to 2 terminal hydroxyl groups per molecule and a number average molecular weight between 1000 and 20,000, an isocyanate having two or more isocyanate groups per molecule. This composition is then reacted with an amine curing agent at 80 to 130.degree. C. to form a cast elastomer with excellent hydrolytic stability. The amine curing agent must be a hindered aromatic amine crosslinker with low polarity and a solubility parameter of less than 10.5.

Abstract: Disclosed is an orthopedic casting material comprising a fabric coated or impregnated with a blend of polyisocyanate prepolymer and an effective detackifying quantity of one or more hydrophilic bisurethanes. In a preferred embodiment, the hydrophilic bisurethane is derived from the reaction of a polyethylene glycol having a molecular weight of about 4000 and methylene-4,4'- bis(phenylisocyanate) to form an isocyanate-terminated prepolymer which is then reacted with ethanol.

Abstract: An orthopedic casting material which is coated on a flexible material as a water-curable prepolymer resin wherein the resin is formed by the reaction of an isocyanate and a polyol where the polyol has a colorant premixed therein and an effective detackifying quantity of one or more hydrophilic bisurethanes is added thereto.