Abstract: Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method includes applying a plurality of laser pulses to the IOL. The laser pulses can be configured to produce, by refractive index writing on the IOL, a predetermined change in phase profile of the IOL to increase spectacle independence.

Abstract: Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method for vergence matching includes calculating vergence of a wave after refraction on a surface of an IOL and, based on an estimated curvature, converting an initial phase map into a vergence-matched phase map, such that the initial phase map follows the curved vergence of the wavefront.

Abstract: Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL) that has a non-zero residual spherical error that requires an estimated diffractive power addition in the IOL. In some embodiments, a plurality of laser pulses are applied to the IOL, the laser pulses being configured to produce, by refractive index writing on the IOL, the estimated diffractive power addition to correct for the residual spherical error.

Abstract: Intraocular lenses for reducing the risk of posterior capsule opacification (PCO) are described herein. PCO can be reduced with an IOL design that increases the pressure at the posterior capsular bend, for example, by including a sharper edge design, an enlarged optical zone, and/or an increased vault height. An example ophthalmic lens can include an optic (200) including an anterior surface (202) defining an anterior side of the optic, a posterior surface (204) defining a posterior side of the optic, and an edge (210) arranged between the anterior and posterior surfaces. The edge and the posterior surface can form an angle, where the angle is less than about 90 degrees. Additionally, the ophthalmic lens can have an increased vault height. At least one of the angle or the increased vault height be configured to increase pressure on a capsular bend in a subject's eye.

Abstract: A ring halometer system configured to quantify dysphotopsias in a patient. The system includes a white screen and a first light source configured to emit a glare source from the white screen. The glare source is configured to form a veil of light visible to the patient when the glare source interacts with an optical surface of the eye of the patient. The system also includes a second light source configured to project a light ring with varying luminance concentric with the glare light source on the white screen, and a controller coupled to the second light source configured to adjust a size of the light ring. The system may also include an electronic device configured to determine a level of bothersomeness of the dysphotopsias experienced by the patient based on the size of the light ring.

Abstract: Apparatuses, systems, and methods for providing improved intraocular lenses (IOLs) and other refractive treatment modalities involve fabricating the IOL or developing the treatment based on a refractive profile. Exemplary techniques include obtaining a base wavefront power profile corresponding to a theoretical lens, adding a second wavefront profile defined by the combination of one or more zones described by a cosine function to obtain a final wavefront power profile, determining a refractive profile based on the final wavefront power profile, and fabricating the intraocular lens or determining the treatment based on the refractive profile.

Abstract: Apparatuses, systems, and methods directed to reducing negative dysphotopsia in an individual's eye. Such apparatuses, systems, and methods may include determining an angle kappa of an individual's eye. Such apparatuses, systems, and methods further include tilt adjustable intraocular lenses.

Abstract: Apparatuses, systems and methods for providing improved intraocular lenses (IOLs), include features for reducing side effects, such as halos, glare and best focus shifts, in multifocal refractive lenses and extended depth of focus lenses. Exemplary ophthalmic lenses can include a continuous, power progressive aspheric surface based on two or more merged optical zones, the aspheric surface being defined by a single aspheric equation. Continuous power progressive intraocular lenses can mitigate optical side effects that typically result from abrupt optical steps. Aspheric power progressive and aspheric extended depth of focus lenses can be combined with diffractive lens profiles to further enhance visual performance while minimizing dysphotopsia effects.

Abstract: Lenses and methods are provided for improving peripheral and/or central vision for patients who suffer from certain retinal conditions that reduce central vision or patients who have undergone cataract surgery. The lens is configured to improve vision by having an optic configured to focus light incident along a direction parallel to an optical axis at the fovea in order to produce a functional foveal image. The optic is configured to focus light incident on the patient's eye at an oblique angle with respect to the optical axis at a peripheral retinal location disposed at a distance from the fovea, the peripheral retinal location having an eccentricity between ?30 degrees and 30 degrees. The image quality at the peripheral retinal location is improved by reducing at least one optical aberration at the peripheral retinal location. The method for improving vision utilizes ocular measurements to iteratively adjust the shape factor of the lens to reduce peripheral refractive errors.

Abstract: Intraocular lenses for reducing negative dysphotpsia (ND) are described herein. An example ophthalmic lens can include an optic (200) with a central optical zone (225) disposed about the optical axis (OA) and an attenuation optical zone (220) disposed about the central optical zone (225), wherein the attenuation optical zone (220) is contiguous with the central optical zone (225), and wherein optical power of the ophthalmic lens is gradually reduced within the attenuation optical zone (220).

Abstract: Lenses and methods are provided for improving peripheral and/or central vision for patients who suffer from certain retinal conditions that reduce central vision or patients who have undergone cataract surgery. The lens is configured to improve vision by having an optic configured to focus light incident along a direction parallel to an optical axis at the fovea in order to produce a functional foveal image. The optic is configured to focus light incident on the patient's eye at an oblique angle with respect to the optical axis at a peripheral retinal location disposed at a distance from the fovea, the peripheral retinal location having an eccentricity between ?30 degrees and 30 degrees. The image quality at the peripheral retinal location is improved by reducing at least one optical aberration at the peripheral retinal location. The method for improving vision utilizes ocular measurements to iteratively adjust the shape factor of the lens to reduce peripheral refractive errors.

Abstract: Apparatuses, systems and methods for providing improved intraocular lenses (IOLs), include features for reducing side effects, such as halos, glare and best focus shifts, in multifocal refractive lenses and extended depth of focus lenses. Exemplary ophthalmic lenses can include a continuous, power progressive aspheric surface based on two or more merged optical zones, the aspheric surface being defined by a single aspheric equation. Continuous power progressive intraocular lenses can mitigate optical side effects that typically result from abrupt optical steps. Aspheric power progressive and aspheric extended depth of focus lenses can be combined with diffractive lens profiles to further enhance visual performance while minimizing dysphotopsia effects. The combination can provide an increased depth of focus that is greater than an individual depth of focus of either the refractive profile or the diffractive profile.

Abstract: A system, method, and apparatus are provided for designing and evaluating intraocular lenses for a large field of view that generate a first eye model from data that includes constant and customized values, including customized values of a first intraocular lens. A simulated outcome is provided by the first intraocular lens in at least one modeled eye. A second eye model is generated wherein a second intraocular lens is substituted for the first intraocular lens. An outcome provided by the second intraocular lens is simulated in at least one modeled eye. Outcomes of the first and second intraocular lenses are compared.

Abstract: Systems and methods for evaluating ND are described herein. An example method can include constructing a non-sequential (NSC) ray-tracing model of an eye with an ophthalmic lens, and modelling a light source and a detector. The detector can be configured to mimic a retina of the eye. The method can also include computing irradiance data using the light source, the NSC ray-tracing model, and the detector. Irradiance data can be computed for each of a plurality of pupil sizes. The method can further include evaluating ND by analyzing the respective irradiance data for each of the pupil sizes. Also described herein are methods for designing an ophthalmic lens edge that reduces the incidence of ND for a given ophthalmic lens by adjusting the edge thickness and/or the scatter.

Abstract: Intraocular lenses for reducing the risk of posterior capsule opacification (PCO) are described herein. PCO can be reduced with an IOL design that increases the pressure at the posterior capsular bend, for example, by including a sharper edge design, an enlarged optical zone, and/or an increased vault height. An example ophthalmic lens can include an optic (200) including an anterior surface (202) defining an anterior side of the optic, a posterior surface (204) defining a posterior side of the optic, and an edge (210) arranged between the anterior and posterior surfaces. The edge and the posterior surface can form an angle, where the angle is less than about 90 degrees. Additionally, the ophthalmic lens can have an increased vault height. At least one of the angle or the increased vault height be configured to increase pressure on a capsular bend in a subject's eye.

Abstract: A system, method, and apparatus are provided for designing and evaluating intraocular lenses for a large field of view that generate a first eye model from data that includes constant and customized values, including customized values of a first intraocular lens. A simulated outcome is provided by the first intraocular lens in at least one modeled eye. A second eye model is generated wherein a second intraocular lens is substituted for the first intraocular lens. An outcome provided by the second intraocular lens is simulated in at least one modeled eye. Outcomes of the first and second intraocular lenses are compared.

Abstract: Apparatuses, systems and methods for providing improved intraocular lenses (IOLs), include features for reducing side effects, such as halos, glare and best focus shifts, in multifocal refractive lenses and extended depth of focus lenses. Exemplary ophthalmic lenses can include a continuous, power progressive aspheric surface based on two or more merged optical zones, the aspheric surface being defined by a single aspheric equation. Continuous power progressive intraocular lenses can mitigate optical side effects that typically result from abrupt optical steps. Aspheric power progressive and aspheric extended depth of focus lenses can be combined with diffractive lens profiles to further enhance visual performance while minimizing dysphotopsia effects. The combination can provide an increased depth of focus that is greater than an individual depth of focus of either the refractive profile or the diffractive profile.

Abstract: Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL) that has a non-zero residual spherical error that requires an estimated diffractive power addition in the IOL. In some embodiments, a plurality of laser pulses are applied to the IOL, the laser pulses being configured to produce, by refractive index writing on the IOL, the estimated diffractive power addition to correct for the residual spherical error.

Abstract: Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method of treating an ocular disease of a subject having an implanted intraocular lens (IOL) includes determining visual needs of a subject that are associated with an ocular disease of the subject determining a pattern of a plurality of pulses of radiation to apply, by refractive index writing, and applying the plurality of pulses of radiation to the one or more selected areas of the IOL.

Abstract: Systems and methods for improving vision of a subject implanted with an intraocular lens (IOL). In some embodiments, a method includes determining at least one photic phenomenon experienced by the subject after implantation of the IOL; and applying a plurality of laser pulses to the IOL, the laser pulses being configured to produce, by refractive index writing on the IOL, a phase shift in the IOL to compensate for the photic phenomenon.