Patents by Inventor Aixian WANG

Aixian WANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11953500
    Abstract: The present invention provides a detection reagent and therapeutic target for B cell tumor after targeted therapy and related applications. The reagent composition comprises 3 groups of antibodies, with the first group of antibodies including an anti-CD38 antibody, an anti-CD10 antibody, an anti-CD34 antibody, an anti-CD19 antibody, an anti-CD24 an antibody, an anti-CD20 antibody, an anti-CD81 antibody, an anti-CD45 antibody; the second group of antibodies including an anti-CD38 antibody, an anti-CD10 antibody, an anti-CD34 antibody, an anti-CD19 antibody, an anti-CD20 antibody, an anti-CD72 antibody, an anti-CD45 antibody; and the third group of antibodies including an anti-cytoplasmic CD79a antibody. The reagent composition of the present invention can be applied for the detection of B-lymphocyte tumors after targeted therapy by flow cytometry.
    Type: Grant
    Filed: May 25, 2022
    Date of Patent: April 9, 2024
    Assignees: Synarc Research Laboratory (Beijing) Ltd., HEBEI YANDA LUDAOPEI HOSPITAL
    Inventors: Hui Wang, Man Chen, Aixian Wang, Meiwei Gong, Xueying Wu, Junyi Zhen, Qing Du, Ya Guo
  • Publication number: 20230408524
    Abstract: The present invention provides a reagent composition for detection of a non-hematopoietic tumor and use thereof. Said reagent composition includes three sets of antibodies, with the first set of antibodies including an anti-CD9 antibody, an anti-GD2 antibody, an anti-CD3 antibody, an anti-CD4 antibody, an anti-CD56 antibody, an anti-CD36 antibody, an anti-CD81, and an anti-CD45 antibody; the second set of antibodies including an anti-HLA-ABC antibody, an anti-CD38 antibody, an anti-CD19 antibody, an anti-CD56 antibody, an anti-CD36 antibody, an anti-CD7 antibody, and an anti-CD45 antibody; the third set of antibodies including anti-cytoplasmic cytokeratin antibodies; wherein the first set of antibodies and the second set of antibodies are respectively used for samples in separate tubes, and the third set of antibodies is used for the sample in the same tube as the second set of antibodies.
    Type: Application
    Filed: June 14, 2023
    Publication date: December 21, 2023
    Applicants: Synarc Research Laboratory (Beijing) Ltd., HEBEI YANDA LUDAOPEI HOSPITAL
    Inventors: Hui Wang, Man Chen, Aixian Wang, Meiwei Gong, Xueying Wu, Junyi Zhen, Qing Du, Ya Guo
  • Publication number: 20230074660
    Abstract: The present invention provides a detection reagent and therapeutic target for B cell tumor after targeted therapy and related applications. The reagent composition comprises 3 groups of antibodies, with the first group of antibodies including an anti-CD38 antibody, an anti-CD10 antibody, an anti-CD34 antibody, an anti-CD19 antibody, an anti-CD24 an antibody, an anti-CD20 antibody, an anti-CD81 antibody, an anti-CD45 antibody; the second group of antibodies including an anti-CD38 antibody, an anti-CD10 antibody, an anti-CD34 antibody, an anti-CD19 antibody, an anti-CD20 antibody, an anti-CD72 antibody, an anti-CD45 antibody; and the third group of antibodies including an anti-cytoplasmic CD79a antibody. The reagent composition of the present invention can be applied for the detection of B-lymphocyte tumors after targeted therapy by flow cytometry.
    Type: Application
    Filed: May 25, 2022
    Publication date: March 9, 2023
    Applicants: Synarc Research Laboratory (Beijing) Ltd., HEBEI YANDA LUDAOPEI HOSPITAL
    Inventors: Hui WANG, Man CHEN, Aixian WANG, Meiwei GONG, Xueying WU, Junyi ZHEN, Qing DU, Ya GUO
  • Publication number: 20230074613
    Abstract: Disclosed are an antibody combination for one-step screening and/or diagnosis of clonal diseases and application thereof. The antibody combination includes eight groups of antibodies, and is a set of flow cytometry detection panels for one-step screening and/or diagnosis of clonal diseases, and 5-tube parallel is used for one sample, the first group of antibodies and the second group of antibodies are used for samples in different flow cytometry tubes, the third group of antibodies and the sixth group of antibodies are used for samples in the same flow cytometry tube, the fourth group of antibodies and the seventh group of antibodies are used for samples in the same flow cytometry tube, and the fifth group of antibodies and the eighth group of antibodies are used for samples in the same flow cytometry tube.
    Type: Application
    Filed: August 3, 2022
    Publication date: March 9, 2023
    Applicants: SYNARC RESEARCH LABORATORY (BEIJING) LTD., HEBEI YANDA LU DAOPEI HOSPITAL
    Inventors: Hui WANG, Man CHEN, Aixian WANG, Meiwei GONG, Xueying WU, Junyi ZHEN, Qing DU, Ya GUO
  • Patent number: 11561300
    Abstract: A close-range microwave imaging method includes: implementing Fourier transform in a pre-set rotation axis direction on an echo signal reflected from a target object and acquired by rotating an array antenna around the pre-set rotation axis to obtain a first echo signal, wherein the first echo signal is represented in polar coordinates; multiplying the first echo signal by a pre-set reference function to obtain a second echo signal; converting the second echo signal into rectangular coordinates by a pre-set algorithm to obtain a third echo signal; and implementing three-dimensional Fourier transform on the third echo signal to obtain three-dimensional image data of the target object. By means of the method, three-dimensional image data of a target object can be obtained fast, fast imaging of the target object can be realized, the data processing amount is small, the imaging precision is high and the method is easy to implement.
    Type: Grant
    Filed: September 4, 2017
    Date of Patent: January 24, 2023
    Assignees: CHINA COMMUNICATION TECHNOLOGY CO., LTD., SHENZHEN VICTOOTH TERAHERTZ TECHNOLOGY CO., LTD
    Inventors: Chunchao Qi, Guangsheng Wu, Shukai Zhao, Qian Xiao, Aixian Wang
  • Patent number: 11550078
    Abstract: A GPU-based human body microwave echo simulation method includes: transmitting emulation input parameters from the memory of a CPU host into the display memory of a GPU device; configuring, at the CPU host, parallel computing network parameters to be run at the GPU device; initiating a kernel function for human body microwave echo simulation preset in the CPU host; computing the kernel function in parallel, in a plurality of processing kernels of the GPU device, in a multi-threaded manner, according to the parallel computing network parameters, to obtain simulation echoes of human body microwaves; transmitting the obtained simulation echoes of human body microwaves from the GPU device back to the CPU host. The method makes full use of the characteristic that a GPU can perform parallel computing to accelerate the echo simulation process, greatly improving the real-time performance of echo simulation of a human body microwave scanning and imaging system.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: January 10, 2023
    Assignees: CHINA COMMUNICATTON TECHNOLOGY CO. LTD., SHENZHEN INSTITUTE OF TERAHERTZ TECHNOLOGY AND INNOVATION
    Inventors: Chunchao Qi, Aixian Wang, Hanjiang Chen, Xiongwei Huang, Yanli Liu, Chengyan Jia, Shukai Zhao
  • Patent number: 11531097
    Abstract: A three-dimensional imaging system and method based on rotational scanning is disclosed. The system includes a column-shaped frame with a column-shaped side; a transceiving antenna array element arranged on the column-shaped side that transmits a micro-wave detection signal to a detected object located in the column-shaped frame and receives an echo signal reflected back from the detected object; a signal transceiving device that generates the micro-wave detection signal and sends same to the transceiving antenna array element and processes the echo signal; a rotation control device that controls rotational movement of the transceiving antenna array element so that the transceiving antenna array element transmits the micro-wave detection signal to the detected object in a plurality of angles; and a positioning trigger fixedly arranged on the column-shaped frame and configured to trigger the signal transceiving device when the transceiving antenna array element arrives at a position of the positioning trigger.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: December 20, 2022
    Assignees: CHINA COMMUNICATION TECHNOLOGY CO., LTD., SHENZHEN INSTITUTE OF TERAHERTZ TECHNOLOGY AND INNOVATION
    Inventors: Chunchao Qi, Aixian Wang, Hanjiang Chen, Jiaqi Ruan, Juncheng Liu, Qian Xiao, Wei Chen, Shukai Zhao
  • Patent number: 11529067
    Abstract: A security check method includes: pre-creating at least four concurrently operating threads, one thread being responsible for movement control and data acquisition, one thread being responsible for imaging processing, one thread being responsible for interface displaying, and one thread being responsible for target detection and recognition; then the four concurrently operating threads divide original echo data of a human body to be checked into data of a plurality of adjacent overlapped azimuthal segments during data processing and perform individual processing on the data of each azimuthal segment. The security check system includes a thread creating unit, a first thread parallel unit, a second thread parallel unit, a third thread parallel unit, a fourth thread parallel unit, and a thread loop control unit. Because subsequent data processing is not required to be performed after the acquisition of all data is completed, the time for a security check process is reduced.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: December 20, 2022
    Assignees: CHINA COMMUNICATION TECHNOLOGY CO., LTD., SHENZHEN INSTITUTE OF TERAHERTZ TECHNOLOGY AND INNOVATION
    Inventors: Chunchao Qi, Aixian Wang, Hanjiang Chen, Tiansheng Zhang, Zhihui Feng, Hu Yuan, Shukai Zhao
  • Patent number: 11215697
    Abstract: An amplitude-phase correction method and system for a microwave imaging system are provided. The method comprises: carrying out data processing, in a range direction, on an echo signal reflected from a target object and acquired by a linear array antenna according to a first pre-set algorithm to obtain a compressed signal in the range direction; extracting a range value corresponding to the maximum amplitude, in the range direction, of the compressed signal in the range direction; carrying out time delay compensation on the echo signal according to the range value to obtain a time-delay-compensated signal; carrying out data processing on the time-delay-compensated signal according to a second pre-set algorithm to obtain an amplitude-phase signal; and carrying out amplitude-phase correction on the echo signal according to the time-delay-compensated signal and the amplitude-phase signal to obtain a corrected echo signal.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: January 4, 2022
    Assignees: Shenzhen Institute of Terahertz Technology and Innovation, Shenzhen Victooth Terahertz Technology Co., Ltd.
    Inventors: Chunchao Qi, Guangsheng Wu, Shukai Zhao, Qian Xiao, Aixian Wang
  • Patent number: 11215730
    Abstract: A close range microwave imaging method and system is provided. The method comprises: controlling a linear antenna array consisting of a preset number of antennas to rotate along a preset arc trajectory so as to scan a target region; controlling the linear antenna array to acquire a preset number of echo data at azimuthal positions on the arc trajectory and to send an echo data set constituted by the preset number of echo data to a signal processing device until the linear antenna array completes the acquisition of echo data at preset azimuthal positions on the arc trajectory; and controlling, every time the signal processing device receives the echo data set, the signal processing device to perform imaging processing on the echo data set.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: January 4, 2022
    Assignees: CHINA COMMUNICATION TECHNOLOGY CO., LTD., Shenzhen Institute of Terahertz Technology and Innovation
    Inventors: Chunchao Qi, Aixian Wang, Hanjiang Chen, Lingxia Guo, Chao Sun, Xiaoxiang Hou, Shukai Zhao
  • Patent number: 11199612
    Abstract: Provided are a direct wave suppression method and system for a microwave imaging system. The method includes a series of filtering operations, such as conversion from a frequency domain to a time domain, filtering, conversion from the time domain to the frequency domain, and cancellation subtraction, on an echo signal set composed of echo signals obtained by a vertical linear array antenna at all the equivalent antenna collection positions thereof.
    Type: Grant
    Filed: September 4, 2017
    Date of Patent: December 14, 2021
    Assignees: Shenzhen Victooth Terahertz Technology Co., Ltd., Shenzhen Institute of Terahertz Technology and Innovation
    Inventors: Chunchao Qi, Guangsheng Wu, Shukai Zhao, Qian Xiao, Aixian Wang
  • Publication number: 20200150265
    Abstract: A close-range microwave imaging method includes: implementing Fourier transform in a pre-set rotation axis direction on an echo signal reflected from a target object and acquired by rotating an array antenna around the pre-set rotation axis to obtain a first echo signal, wherein the first echo signal is represented in polar coordinates; multiplying the first echo signal by a pre-set reference function to obtain a second echo signal; converting the second echo signal into rectangular coordinates by a pre-set algorithm to obtain a third echo signal; and implementing three-dimensional Fourier transform on the third echo signal to obtain three-dimensional image data of the target object. By means of the method, three-dimensional image data of a target object can be obtained fast, fast imaging of the target object can be realized, the data processing amount is small, the imaging precision is high and the method is easy to implement.
    Type: Application
    Filed: September 4, 2017
    Publication date: May 14, 2020
    Applicant: Shenzhen Vlctooth Terahertz Technology Co., Ltd.
    Inventors: Chunchao QI, Guangsheng WU, Shukai ZHAO, Qian XIAO, Aixian WANG
  • Publication number: 20200142030
    Abstract: An amplitude-phase correction method and system for a microwave imaging system are provided. The method comprises: carrying out data processing, in a range direction, on an echo signal reflected from a target object and acquired by a linear array antenna according to a first pre-set algorithm to obtain a compressed signal in the range direction; extracting a range value corresponding to the maximum amplitude, in the range direction, of the compressed signal in the range direction; carrying out time delay compensation on the echo signal according to the range value to obtain a time-delay-compensated signal; carrying out data processing on the time-delay-compensated signal according to a second pre-set algorithm to obtain an amplitude-phase signal; and carrying out amplitude-phase correction on the echo signal according to the time-delay-compensated signal and the amplitude-phase signal to obtain a corrected echo signal.
    Type: Application
    Filed: September 7, 2017
    Publication date: May 7, 2020
    Inventors: Chunchao Qi, Guangsheng Wu, Shukai Zhao, Qian Xiao, Aixian Wang
  • Publication number: 20200142053
    Abstract: Provided are a direct wave suppression method and system for a microwave imaging system. The method includes a series of filtering operations, such as conversion from a frequency domain to a time domain, filtering, conversion from the time domain to the frequency domain, and cancellation subtraction, on an echo signal set composed of echo signals obtained by a vertical linear array antenna at all the equivalent antenna collection positions thereof.
    Type: Application
    Filed: September 4, 2017
    Publication date: May 7, 2020
    Inventors: Chunchao Qi, Guangsheng Wu, Shukai Zhao, Qian Xiao, Aixian Wang
  • Publication number: 20200054236
    Abstract: A security check method includes: pre-creating at least four concurrently operating threads, one thread being responsible for movement control and data acquisition, one thread being responsible for imaging processing, one thread being responsible for interface displaying, and one thread being responsible for target detection and recognition; then the four concurrently operating threads divide original echo data of a human body to be checked into data of a plurality of adjacent overlapped azimuthal segments during data processing and perform individual processing on the data of each azimuthal segment. The security check system includes a thread creating unit, a first thread parallel unit, a second thread parallel unit, a third thread parallel unit, a fourth thread parallel unit, and a thread loop control unit. Because subsequent data processing is not required to be performed after the acquisition of all data is completed, the time for a security check process is reduced.
    Type: Application
    Filed: August 4, 2017
    Publication date: February 20, 2020
    Inventors: Chunchao QI, Aixian WANG, Hanjiang CHEN, Tiansheng ZHANG, Zhihui FENG, Hu YUAN, Shukai ZHAO
  • Publication number: 20200041691
    Abstract: A GPU-based human body microwave echo simulation method includes: transmitting emulation input parameters from the memory of a CPU host into the display memory of a GPU device; configuring, at the CPU host, parallel computing network parameters to be run at the GPU device; initiating a kernel function for human body microwave echo simulation preset in the CPU host; computing the kernel function in parallel, in a plurality of processing kernels of the GPU device, in a multi-threaded manner, according to the parallel computing network parameters, to obtain simulation echoes of human body microwaves; transmitting the obtained simulation echoes of human body microwaves from the GPU device back to the CPU host. The method makes full use of the characteristic that a GPU can perform parallel computing to accelerate the echo simulation process, greatly improving the real-time performance of echo simulation of a human body microwave scanning and imaging system.
    Type: Application
    Filed: August 4, 2017
    Publication date: February 6, 2020
    Inventors: Chunchao QI, Aixian WANG, Hanjiang CHEN, Xiongwei HUANG, Yanli LIU, Chengyan JIA, Shukai ZHAO
  • Publication number: 20190317208
    Abstract: A three-dimensional imaging system and method based on rotational scanning is disclosed. The system includes a column-shaped frame with a column-shaped side; a transceiving antenna array element arranged on the column-shaped side that transmits a micro-wave detection signal to a detected object located in the column-shaped frame and receives an echo signal reflected back from the detected object; a signal transceiving device that generates the micro-wave detection signal and sends same to the transceiving antenna array element and processes the echo signal; a rotation control device that controls rotational movement of the transceiving antenna array element so that the transceiving antenna array element transmits the micro-wave detection signal to the detected object in a plurality of angles; and a positioning trigger fixedly arranged on the column-shaped frame and configured to trigger the signal transceiving device when the transceiving antenna array element arrives at a position of the positioning trigger.
    Type: Application
    Filed: November 16, 2017
    Publication date: October 17, 2019
    Inventors: Chunchao QI, Aixian WANG, Hanjiang CHEN, Jiaqi RUAN, Juncheng LIU, Qian XIAO, Wei CHEN, Shukai ZHAO
  • Publication number: 20190243022
    Abstract: A close range microwave imaging method and system is provided. The method comprises: controlling a linear antenna array consisting of a preset number of antennas to rotate along a preset arc trajectory so as to scan a target region; controlling the linear antenna array to acquire a preset number of echo data at azimuthal positions on the arc trajectory and to send an echo data set constituted by the preset number of echo data to a signal processing device until the linear antenna array completes the acquisition of echo data at preset azimuthal positions on the arc trajectory; and controlling, every time the signal processing device receives the echo data set, the signal processing device to perform imaging processing on the echo data set.
    Type: Application
    Filed: August 4, 2017
    Publication date: August 8, 2019
    Inventors: Chunchao Qi, Aixian Wang, Hanjiang Chen, Lingxia Guo, Chao Sun, Xiaoxiang Hou, Shukai Zhao