Patents by Inventor Aizo Matsushiro

Aizo Matsushiro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pearl protein (nacrein) and process for producing the same
    Patent number: 5968772
    Abstract: A nacrein protein is expressed by separating a protein fraction having a molecular weight of sixty thousand, as determined by SDS-PAGE, from pearl proteins extracted from the nacreous layers of pearl oysters, synthesizing a probe coding for the N-terminal amino acid sequence of the protein in this fraction, cloning the cDNA derived from the mRNA of the mantle of the pearl oyster and hybridizable with the synthesized probe, and introducing the cloned cDNA into the host cells of Escherichia coli.
    Type: Grant
    Filed: January 13, 1998
    Date of Patent: October 19, 1999
    Inventor: Aizo Matsushiro
  • Vector for expression and secretion of polypeptide microorganism transformed by the vector and production of polypeptide with the same microorganism
    Patent number: 5545564
    Abstract: This present invention provides a vector for expression and secretion of a polypeptide by directly joining a DNA sequence coding for a signal peptide to a DNA sequence coding for the desired polypeptide, the vector containing the DNA sequence coding for the signal peptide, a vector for expression and secretion of the desired polypeptide as defined above and further having incorporated therein the DNA sequence coding for the desired polypeptide, a microorganism transformed by the secretion vector, and a process for producing the desired polypeptide by growing the microorganism.
    Type: Grant
    Filed: February 24, 1995
    Date of Patent: August 13, 1996
    Assignee: Earth Chemical Company, Ltd.
    Inventors: Hideo Ohgai, Hiroshi Momota, Takeshi Kumakura, Noriyuki Kajifusa, Toshiki Kitazawa, Kazuhide Oshiden, Aizo Matsushiro
  • Compositions containing lactic acid bacterium Streptococcus salivarius
    Patent number: 5468479
    Abstract: Disclosed are compositions such as foods and pharmaceuticals, and methods of their production, comprising at least one lactic acid bacterium capable of assisting in intestinal regulation and preventing dental caries. The bacterium is an isolated living Streptococcus salivarius strain identified as FERM BP-3885 and is further capable of producing dextranase while persisting in the oral cavity.
    Type: Grant
    Filed: June 26, 1992
    Date of Patent: November 21, 1995
    Assignees: Toshio Kawanishi, Kazusumi Tsutsumi
    Inventor: Aizo Matsushiro
  • DNA encoding glucanase enzymes
    Patent number: 5306639
    Abstract: Disclosed is the isolation and cloning of genes encoding glucanohydrolase enzymes and the expression and secretion of exogenous glucanase gene products in host cells.
    Type: Grant
    Filed: October 8, 1991
    Date of Patent: April 26, 1994
    Inventor: Aizo Matsushiro
  • Purified glucanase enzymes
    Patent number: 5290916
    Abstract: Disclosed is the isolation and cloning of genes encoding glucanohydrolase enzymes and the expression and secretion of exogenous glucanase gene products in host cells.
    Type: Grant
    Filed: April 20, 1992
    Date of Patent: March 1, 1994
    Inventor: Aizo Matsushiro