Patents by Inventor Ajay Gopinath

Ajay Gopinath has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240177829
    Abstract: In part, the invention relates to a method for sizing a stent for placement in a vessel. In one embodiment, the method includes the steps of: dividing the vessel into a plurality of segments, each segment being defined as the space between branches of the vessel; selecting a starting point that appears to have substantially no disease; defining the diameter at this point to be the maximum diameter; calculating the maximal diameter of the next adjacent segment according to a power law; measuring the actual diameter of the next adjacent segment; selecting either the calculated maximum diameter or the measured maximum diameter depending upon which diameter is larger; using the selected maximum diameter to find the maximum diameter of this next segment; iteratively proceeding until the entire length of the vessel is examined; and selecting a stent in response to the diameters of the end proximal and distal segments.
    Type: Application
    Filed: February 2, 2024
    Publication date: May 30, 2024
    Applicant: LightLab Imaging, Inc.
    Inventors: Joseph M. Schmitt, Hiram Bezerra, Christopher Petroff, Ajay Gopinath
  • Publication number: 20240130793
    Abstract: In part, the disclosure relates to determining a stent deployment location and other parameters using blood vessel data. Stent deployment can be planned such that the amount of blood flow restored from stenting relative to an unstented vessel increases one or more metrics. An end user can specify one or more stent lengths, including a range of stent lengths. In turn, diagnostic tools can generate candidate virtual stents having lengths within the specified range suitable for placement relative to a vessel representation. Blood vessel distance values such as blood vessel diameter, radius, area values, chord values, or other cross-sectional, etc. its length are used to identify stent landing zones. These tools can use or supplement angiography data and/or be co-registered therewith. Optical imaging, ultrasound, angiography or other imaging modalities are used to generate the blood vessel data.
    Type: Application
    Filed: December 7, 2023
    Publication date: April 25, 2024
    Applicant: LightLab Imaging, Inc.
    Inventor: Ajay Gopinath
  • Publication number: 20240099585
    Abstract: The present disclosure provides systems and methods for determining a mean transit time of a bolus within the blood vessel by passing the bolus through the blood vessel while an intravascular imaging probe is held stationary. The probe may collect a plurality of image frames as the bolus passes the probe. The cross-sectional area of the bolus within the images frames may be determined by segmenting each image frame by thresholding, creating a vessel mask, and creating a contrast mask by applying an element-wise AND operator to the thresholded image and the vessel mask. The cross-sectional area of the bolus for the image frames may be plotted on an area dilution curve. Various fits may be applied to and various points may be identified on the area dilution curve. The various fits and points may be used to determine the mean transit time.
    Type: Application
    Filed: December 17, 2021
    Publication date: March 28, 2024
    Inventors: Justin Akira Blaber, Ajay Gopinath, Wei Chiu
  • Publication number: 20240095675
    Abstract: An example operation may include one or more of acquiring, by a retailer node, an inventory data from a supplier node over a blockchain network, receiving, by the retailer node, outstanding orders data of the supplier node, generating, by the retailer node, an order distribution policy based on the inventory data and the outstanding orders data, and executing a smart contract to order goods from the supplier node based on the ordering policy.
    Type: Application
    Filed: November 19, 2023
    Publication date: March 21, 2024
    Inventors: Elisabeth Claire Paulson, Ashish Jagmohan, Ajay Ashok Deshpande, Pavithra Harsha, Ali Koc, Krishna Chaitanya Ratakonda, Ramesh Gopinath
  • Patent number: 11923067
    Abstract: In part, the invention relates to a method for sizing a stent for placement in a vessel. In one embodiment, the method includes the steps of: dividing the vessel into a plurality of segments, each segment being defined as the space between branches of the vessel; selecting a starting point that appears to have substantially no disease; defining the diameter at this point to be the maximum diameter; calculating the maximal diameter of the next adjacent segment according to a power law; measuring the actual diameter of the next adjacent segment; selecting either the calculated maximum diameter or the measured maximum diameter depending upon which diameter is larger; using the selected maximum diameter to find the maximum diameter of this next segment; iteratively proceeding until the entire length of the vessel is examined; and selecting a stent in response to the diameters of the end proximal and distal segments.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: March 5, 2024
    Assignee: LightLab Imaging, Inc.
    Inventors: Joseph M. Schmitt, Hiram Bezerra, Christopher Petroff, Ajay Gopinath
  • Publication number: 20240057870
    Abstract: In part, the disclosure relates to method of displaying a representation of an artery. The method may include storing an intravascular image dataset in a memory device of a diagnostic imaging system, the intravascular image dataset generated in response to intravascular imaging of a segment of an artery; automatically detecting lumen boundary of the segment on a per frame basis; automatically detecting EEL and displaying a stent sizing workflow. In part, the disclosure also relates to automatically detecting one or more regions of calcium relative to lumen boundary of the segment; calculating an angular or circumferential measurement of detected calcium for one or more frames; calculating a calcium thickness of detected calcium for one or more frames; and displaying the calcium thickness and the angular or circumferential measurement of detected calcium for a first frame of the one or more frames.
    Type: Application
    Filed: October 31, 2023
    Publication date: February 22, 2024
    Applicant: LightLab Imaging, Inc.
    Inventors: Ajay Gopinath, Mark Hoeveler
  • Publication number: 20240046476
    Abstract: The present disclosure provides systems and methods to receiving OCT or IVUS image data frames to output one or more representations of a blood vessel segment. The image data frames may be stretched and/or aligned using various windows or bins or alignment features. Arterial features, such as the calcium burden, may be detected in each of the image data frames. The arterial features may be scored. The score may be a stent under-expansion risk. The representation may include an indication of the arterial features and their respective score. The indication may be a color coded indication.
    Type: Application
    Filed: October 10, 2023
    Publication date: February 8, 2024
    Applicant: LightLab Imaging, Inc.
    Inventors: Gregory Patrick Amis, Ajay Gopinath, Mark Hoeveler
  • Publication number: 20240036720
    Abstract: In part, the disclosure relates to intravascular data collection systems and the software-based visualization and display of intravascular data relating to detected side branches and side branch obstruction. An estimate of side branch diameter can be made based on a vessel profile or a maximum diameter of a vessel at a distal and proximal location relative to the side branch. A amount of side branch obstruction may be determined by comparing an observed side branch diameter with in the image data with the estimated side branch diameter. In addition, an amount of blood flow obstruction may also be determined.
    Type: Application
    Filed: August 15, 2023
    Publication date: February 1, 2024
    Applicant: LightLab Imaging, Inc.
    Inventors: Ajay Gopinath, Denis Dion, Christopher E. Griffin, Desmond Adler
  • Patent number: 11883107
    Abstract: In part, the disclosure relates to determining a stent deployment location and other parameters using blood vessel data. Stent deployment can be planned such that the amount of blood flow restored from stenting relative to an unstented vessel increases one or more metrics. An end user can specify one or more stent lengths, including a range of stent lengths. In turn, diagnostic tools can generate candidate virtual stents having lengths within the specified range suitable for placement relative to a vessel representation. Blood vessel distance values such as blood vessel diameter, radius, area values, chord values, or other cross-sectional, etc. its length are used to identify stent landing zones. These tools can use or supplement angiography data and/or be co-registered therewith. Optical imaging, ultrasound, angiography or other imaging modalities are used to generate the blood vessel data.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: January 30, 2024
    Assignee: LightLab Imaging, Inc.
    Inventor: Ajay Gopinath
  • Publication number: 20230389799
    Abstract: In part, the disclosure relates to method of displaying a representation of an artery. The method may include storing an intravascular image dataset in a memory device of a diagnostic imaging system, the intravascular image dataset generated in response to intravascular imaging of a segment of an artery; automatically detecting lumen boundary of the segment on a per frame basis; automatically detecting EEL and displaying a stent sizing workflow. In part, the disclosure also relates to automatically detecting one or more regions of calcium relative to lumen boundary of the segment; calculating an angular or circumferential measurement of detected calcium for one or more frames; calculating a calcium thickness of detected calcium for one or more frames; and displaying the calcium thickness and the angular or circumferential measurement of detected calcium for a first frame of the one or more frames.
    Type: Application
    Filed: August 24, 2023
    Publication date: December 7, 2023
    Applicant: LightLab Imaging, Inc.
    Inventors: Ajay Gopinath, Mark Hoeveler
  • Patent number: 11819309
    Abstract: In part, the disclosure relates to method of displaying a representation of an artery. The method may include storing an intravascular image dataset in a memory device of a diagnostic imaging system, the intravascular image dataset generated in response to intravascular imaging of a segment of an artery; automatically detecting lumen boundary of the segment on a per frame basis; automatically detecting EEL and displaying a stent sizing workflow. In part, the disclosure also relates to automatically detecting one or more regions of calcium relative to lumen boundary of the segment; calculating an angular or circumferential measurement of detected calcium for one or more frames; calculating a calcium thickness of detected calcium for one or more frames; and displaying the calcium thickness and the angular or circumferential measurement of detected calcium for a first frame of the one or more frames.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: November 21, 2023
    Assignee: LightLab Imaging, Inc.
    Inventors: Ajay Gopinath, Mark Hoeveler
  • Publication number: 20230326032
    Abstract: In part, the disclosure relates to methods, and systems suitable for evaluating image data from a patient on a real time or substantially real time basis using machine learning (ML) methods and systems. Systems and methods for improving diagnostic tools for end users such as cardiologists and imaging specialists using machine learning techniques applied to specific problems associated with intravascular images that have polar representations. Further, given the use of rotating probes to obtain image data for OCT, IVUS, and other imaging data, dealing with the two coordinate systems associated therewith creates challenges. The present disclosure addresses these and numerous other challenges relating to solving the problem of quickly imaging and diagnosis a patient such that stenting and other procedures may be applied during a single session in the cath lab.
    Type: Application
    Filed: June 1, 2023
    Publication date: October 12, 2023
    Applicant: LightLab Imaging, Inc.
    Inventors: Shimin Li, Ajay Gopinath, Kyle Savidge
  • Patent number: 11768593
    Abstract: In part, the disclosure relates to intravascular data collection systems and the software-based visualization and display of intravascular data relating to detected side branches and side branch obstruction. An estimate of side branch diameter can be made based on a vessel profile or a maximum diameter of a vessel at a distal and proximal location relative to the side branch. A amount of side branch obstruction may be determined by comparing an observed side branch diameter with in the image data with the estimated side branch diameter. In addition, an amount of blood flow obstruction may also be determined.
    Type: Grant
    Filed: February 17, 2022
    Date of Patent: September 26, 2023
    Assignee: LightLab Imaging, Inc.
    Inventors: Ajay Gopinath, Denis Dion, Christopher E. Griffin, Desmond Adler
  • Publication number: 20230274440
    Abstract: In part, the disclosure relates to methods, and systems suitable for evaluating image data from a patient on a real time or substantially real time basis using machine learning (ML) methods and systems. Systems and methods for improving diagnostic tools for end users such as cardiologists and imaging specialists using machine learning techniques applied to specific problems associated with intravascular images that have polar representations. Further, given the use of rotating probes to obtain image data for OCT, IVUS, and other imaging data, dealing with the two coordinate systems associated therewith creates challenges. The present disclosure addresses these and numerous other challenges relating to solving the problem of quickly imaging and diagnosis a patient such that stenting and other procedures may be applied during a single session in the cath lab.
    Type: Application
    Filed: May 4, 2023
    Publication date: August 31, 2023
    Applicant: LightLab Imaging, Inc.
    Inventors: Shimin Li, Ajay Gopinath, Kyle Savidge
  • Patent number: 11741613
    Abstract: In part, the disclosure relates to methods, and systems suitable for evaluating image data from a patient on a real time or substantially real time basis using machine learning (ML) methods and systems. Systems and methods for improving diagnostic tools for end users such as cardiologists and imaging specialists using machine learning techniques applied to specific problems associated with intravascular images that have polar representations. Further, given the use of rotating probes to obtain image data for OCT, IVUS, and other imaging data, dealing with the two coordinate systems associated therewith creates challenges. The present disclosure addresses these and numerous other challenges relating to solving the problem of quickly imaging and diagnosis a patient such that stenting and other procedures may be applied during a single session in the cath lab.
    Type: Grant
    Filed: December 23, 2021
    Date of Patent: August 29, 2023
    Assignee: LightLab Imaging, Inc.
    Inventors: Shimin Li, Ajay Gopinath, Kyle Savidge
  • Publication number: 20230054891
    Abstract: Systems and methods are disclosed for identifying features of a blood vessel using extravascular and intravascular images in order to estimate a virtual flow reserve (VFR) of the imaged blood vessel. Aspects of the disclosure include using extravascular images to estimate the size of the blood vessel in regions that have not been intravascularly imaged. The VFR estimation may be based on a resistance model that incorporates both the intravascular image data and the estimated blood vessel size. In other aspects, multiangled extravascular images are captured and analyzed in order to identify the size and orientation of branch vessels.
    Type: Application
    Filed: August 18, 2022
    Publication date: February 23, 2023
    Applicant: LightLab Imaging, Inc.
    Inventors: Wei Chiu, Shimin Li, Ajay Gopinath, Jacob Segev, Lorina Dascal
  • Publication number: 20230018499
    Abstract: Aspects of the disclosure relate to systems, methods, and algorithms to train a machine learning model or neural network to classify OCT images. The neural network or machine learning model can receive annotated OCT images indicating which portions of the OCT image are blocked and which are clear as well as a classification of the OCT image as clear or blocked. After training, the neural network can be used to classify one or more new OCT images. A user interface can be provided to output the results of the classification and summarize the analysis of the one or more OCT images.
    Type: Application
    Filed: July 12, 2022
    Publication date: January 19, 2023
    Applicant: LightLab Imaging, Inc.
    Inventors: Justin Akira Blaber, Ajay Gopinath, Humphrey Chen, Kyle Edward Savidge, Angela Zhang, Gregory Patrick Amis
  • Publication number: 20230005139
    Abstract: Aspects of the disclosure provide for methods, systems, and apparatuses, including computer-readable storage media, for lipid detection by identifying fibrotic caps in medical images of blood vessels. A method includes receiving one or more input images of a blood vessel and processing the one or more input images using a machine learning model trained to identify locations of fibrotic caps in blood vessels. The machine learning model is trained using a plurality of training images each annotated with locations of one or more fibrotic caps. A method includes identifying and characterizing fibrotic caps of lipid pools based on differences in radial signal intensities measured at different locations of an input image. A system can generate one or more output images having segments that are visually annotated representing predicted locations of fibrotic caps covering lipidic plaques.
    Type: Application
    Filed: June 30, 2022
    Publication date: January 5, 2023
    Applicant: LightLab Imaging, Inc.
    Inventors: Justin Akira Blaber, Ajay Gopinath, Gregory Patrick Amis, Kyle Savidge
  • Publication number: 20220335616
    Abstract: The present disclosure provides systems and methods to receiving OCT or IVUS image data frames to output one or more representations of a blood vessel segment. The image data frames may be stretched and/or aligned using various windows or bins or alignment features. Arterial features, such as the calcium burden, may be detected in each of the image data frames. The arterial features may be scored. The score may be a stent under-expansion risk. The representation may include an indication of the arterial features and their respective score. The indication may be a color coded indication.
    Type: Application
    Filed: July 6, 2022
    Publication date: October 20, 2022
    Applicant: LightLab Imaging, Inc.
    Inventors: Gregory Patrick Amis, Ajay Gopinath, Mark Hoeveler
  • Patent number: 11475560
    Abstract: In part, the disclosure relates to an automated method of branch detection with regard to a blood vessel imaged using an intravascular modality such as OCT, IVUS, or other imaging modalities. In one embodiment, a representation of A-lines and frames generated using an intravascular imaging system is used to identify candidate branches of a blood vessel. One or more operators such as filters can be applied to remove false positives associated with other detections.
    Type: Grant
    Filed: January 31, 2020
    Date of Patent: October 18, 2022
    Assignee: LightLab Imaging, Inc.
    Inventor: Ajay Gopinath