Patents by Inventor Ajay Karakoti

Ajay Karakoti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9585840
    Abstract: Nanoparticles disclosed in the invention comprise a dextran-coated crystalline structure of cerium oxide wherein tetravalent Ce4+ predominates over trivalent Ce3+ and wherein said nanoparticles have a diameter of approximately from 3 to 5 nm. The nanoparticles exhibit both superoxide dismutase activity and catalase activity in an environment having a substantially neutral or acidic pH. The nanoparticles may be used to make and may be contained in a medication. The subject nanoparticles are useful in a method of promoting a cytotoxic anti-invasive effect on squamous tumor cells and inhibit tumor invasiveness.
    Type: Grant
    Filed: July 13, 2012
    Date of Patent: March 7, 2017
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Peter Brenneisen, Sudipta Seal, Ajay Karakoti
  • Patent number: 9388074
    Abstract: Processes and methods of making and preparing, compositions and structural products therefrom are provided, whereby the surface area of alumino-silicate based powders is greatly increased and rendered chemically active so that when the functionalized powders are mixed with water poly-condensation reactions occur between the surfaces binding the powders together to form a structural material with negligible emission of carbon compounds. In another embodiment, the surface functionalized powders can be mixed with an additive; a dry aggregate, such as sand and water to make a slurry that can be poured or cast into any desired shape and rapidly cured to a hardened shape suitable for use as a structural material with the mechanical strength equivalent to Portland-cement based concrete products.
    Type: Grant
    Filed: December 16, 2008
    Date of Patent: July 12, 2016
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Sudipta Seal, Larry L. Hench, Suresh Babu Krishna Moorthy, David Reid, Ajay Karakoti
  • Patent number: 8916199
    Abstract: The invention provides a method of treating ovarian cancer in a mammal, the method inhibits angiogenesis associated with the cancer and comprises the parenteral administration to the mammal of an effective amount of cerium oxide nanoparticles having a predominance of Ce+3.
    Type: Grant
    Filed: July 14, 2011
    Date of Patent: December 23, 2014
    Assignee: University of Central Florida Research Foundation, Ind.
    Inventors: Sudipta Seal, Ajay Karakoti, Vijayalakshmi Shridhar, Shailendra Giri
  • Publication number: 20140356271
    Abstract: Disclosed herein are methods and materials for influencing proliferation of stem cells. Specifically exemplified herein are compositions comprising cerium oxide nanoparticles which can be used to stimulate proliferation of stem cells under common culture conditions, or which can be utilized to improve therapeutic outcomes.
    Type: Application
    Filed: June 10, 2014
    Publication date: December 4, 2014
    Applicant: University of Central Florida Research Foundation, Inc.
    Inventors: Sudipta Seal, Ajay Karakoti
  • Publication number: 20110112272
    Abstract: Processes and methods of making and preparing, compositions and structural products therefrom are provided, whereby the surface area of alumino-silicate based powders is greatly increased and rendered chemically active so that when the functionalized powders are mixed with water poly-condensation reactions occur between the surfaces binding the powders together to form a structural material with negligible emission of carbon compounds. In another embodiment, the surface functionalized powders can be mixed with an additive; a dry aggregate, such as sand and water to make a slurry that can be poured or cast into any desired shape and rapidly cured to a hardened shape suitable for use as a structural material with the mechanical strength equivalent to Portland-cement based concrete products.
    Type: Application
    Filed: December 16, 2008
    Publication date: May 12, 2011
    Applicant: University of Central Florida Research Foundation, Inc.
    Inventors: Sudipta Seal, Larry L. Hench, Suresh Babu Krishna Moorthy, David Reid, Ajay Karakoti