Patents by Inventor Ajda PODGORSEK BERKE

Ajda PODGORSEK BERKE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES CHARACTERIZED BY INSUFFICIENT PANTOTHENATE KINASE ACTIVITY

Publication number: 20220133753

Abstract: Methods and pharmaceutical compositions for use in treating diseases associated with insufficient activity of the pantothenate kinase enzyme (e.g., CASTOR diseases) are disclosed. The methods and compositions involve an effective amount of an active derivative of 4?-phosphopantetheine.

Type: Application

Filed: June 7, 2021

Publication date: May 5, 2022

Inventors: Gregor KOSEC, Ajda Podgorsek BERKE, Hrvoje PETKOVIC, Oda Cornelia Maria SIBON, Balaji SRINIVASAN, Susan J. HAYFLICK
COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES CHARACTERIZED BY INSUFFICIENT PANTOTHENATE KINASE ACTIVITY

Publication number: 20190255079

Abstract: Methods and pharmaceutical compositions for use in treating diseases associated with insufficient activity of the pantothenate kinase enzyme (e.g., CASTOR diseases) are disclosed. The methods and compositions involve an effective amount of an active derivative of 4?-phosphopantetheine.

Type: Application

Filed: June 16, 2017

Publication date: August 22, 2019

Inventors: Gregor KOSEC, Ajda Podgorsek BERKE, Hrvoje PETKOVIC, Oda Cornelia Maria SIBON, Balaji SRINIVASAN, Susan J. HAYFLICK
Stable pantetheine derivatives for the treatment of pantothenate kinase associated neurodegeneration (PKAN) and methods for the synthesis of such compounds

Patent number: 9963472

Abstract: The invention relates to (S)-acyl-4?-phosphopantetheine derivatives, methods of their synthesis, and related medical uses of such compounds. Preferred medical uses relate to the treatment of neurodegenerative diseases, such as PKAN.

Type: Grant

Filed: October 29, 2014

Date of Patent: May 8, 2018

Assignees: ACIES BIO D.O.O., RIJKSUNIVERSITEIT GRONINGEN, ACADEMISCH ZIEKENHUIS GRONINGEN

Inventors: Branko Jenko, Gregor Kosec, Hrvoje Petkovic, Ajda Podgorsek Berke, Jerca Pahor, Alen Cusak, Oda Cornelia Maria Sibon, Balaji Srinivasan
STABLE PANTETHEINE DERIVATIVES FOR THE TREATMENT OF PANTOTHENATE KINASE ASSOCIATED NEURODEGENERATION (PKAN) AND METHODS FOR THE SYNTHESIS OF SUCH COMPOUNDS

Publication number: 20180118767

Abstract: The invention relates to (S)-acyl-4?-phosphopantetheine derivatives, methods of their synthesis, and related medical uses of such compounds. Preferred medical uses relate to the treatment of neurodegenerative diseases, such as PKAN.

Type: Application

Filed: December 21, 2017

Publication date: May 3, 2018

Inventors: Branko JENKO, Gregor KOSEC, Hrvoje PETKOVIC, Ajda Podgorsek BERKE, Jerca PAHOR, Alen CUSAK, Oda Cornelia Maria SIBON, Balaji SRINIVASAN
STABLE PANTETHEINE DERIVATIVES FOR THE TREATMENT OF PANTOTHENATE KINASE ASSOCIATED NEURODEGENERATION (PKAN) AND METHODS FOR THE SYNTHESIS OF SUCH COMPOUNDS

Publication number: 20160297840

Abstract: The invention relates to (S)-acyl-4?-phosphopantetheine derivatives, methods of their synthesis, and related medical uses of such compounds. Preferred medical uses relate to the treatment of neurodegenerative diseases, such as PKAN.

Type: Application

Filed: October 29, 2014

Publication date: October 13, 2016

Inventors: Branko JENKO, Gregor KOSEC, Hrvoje PETKOVIC, Ajda PODGORSEK BERKE, Jerca PAHOR, Alen CUSAK, Oda Cornelia Maria SIBON, Balaji SRINIVASAN

COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES CHARACTERIZED BY INSUFFICIENT PANTOTHENATE KINASE ACTIVITY

COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES CHARACTERIZED BY INSUFFICIENT PANTOTHENATE KINASE ACTIVITY

Stable pantetheine derivatives for the treatment of pantothenate kinase associated neurodegeneration (PKAN) and methods for the synthesis of such compounds

STABLE PANTETHEINE DERIVATIVES FOR THE TREATMENT OF PANTOTHENATE KINASE ASSOCIATED NEURODEGENERATION (PKAN) AND METHODS FOR THE SYNTHESIS OF SUCH COMPOUNDS

STABLE PANTETHEINE DERIVATIVES FOR THE TREATMENT OF PANTOTHENATE KINASE ASSOCIATED NEURODEGENERATION (PKAN) AND METHODS FOR THE SYNTHESIS OF SUCH COMPOUNDS