Ajit Basak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
Abstract: There is provided a NetB epitope polypeptide comprising at least 10 contiguous amino acids from SEQ ID NO:1 and comprising a mutation in at least one position between amino acids 130 and 297 as compared with the equivalent position in SEQ ID NO:3, the mutation preferably being located within a rim domain, the polypeptide being capable of binding an antibody which binds to SEQ ID NO:1 and having reduced toxicity compared with the toxicity of SEQ ID NO:1. The polypeptide is useful to vaccinate a subject against infection by Clostridium perfringens.
Type:
Grant
Filed:
August 22, 2016
Date of Patent:
January 8, 2019
Assignee:
University of Exeter
Inventors:
Richard W. Titball, Sergio Paulo Fernandes Da Costa, Claire Naylor, Ajit Basak
Abstract: There is provided a NetB epitope polypeptide comprising at least 10 contiguous amino acids from SEQ ID NO:1 and comprising a mutation in at least one position between amino acids 130 and 297 as compared with the equivalent position in SEQ ID NO:3, the mutation preferably being located within a rim domain, the polypeptide being capable of binding an antibody which binds to SEQ ID NO:1 and having reduced toxicity compared with the toxicity of SEQ ID NO:1. The polypeptide is useful to vaccinate a subject against infection by Clostridium perfringens.
Type:
Application
Filed:
August 22, 2016
Publication date:
February 23, 2017
Applicant:
University of Exeter
Inventors:
Richard W. Titball, Sergio Paulo Fernandes Da Costa, Claire Naylor, Ajit Basak
Abstract: There is provided a NetB epitope polypeptide comprising at least 10 contiguous amino acids from SEQ ID NO:1 and comprising a mutation in at least one position between amino acids 130 and 297 as compared with the equivalent position in SEQ ID NO:3, the mutation preferably being located within a rim domain, the polypeptide being capable of binding an antibody which binds to SEQ ID NO:1 and having reduced toxicity compared with the toxicity of SEQ ID NO:1. The polypeptide is useful to vaccinate a subject against infection by Clostridium perfringens.
Type:
Grant
Filed:
October 24, 2012
Date of Patent:
August 23, 2016
Assignee:
University of Exeter
Inventors:
Richard W. Titball, Sérgio Paulo Fernandes Da Costa, Claire Naylor, Ajit Basak
Abstract: There is provided a NetB epitope polypeptide comprising at least 10 contiguous amino acids from SEQ ID NO:1 and comprising a mutation in at least one position between amino acids 130 and 297 as compared with the equivalent position in SEQ ID the mutation preferably being located within a rim domain, the polypeptide being capable of binding an antibody which binds to SEQ ID NO:1 and having reduced toxicity compared with the toxicity of SEQ ID NO:1. The polypeptide is useful to vaccinate a subject against infection by Clostridium perfringens.
Type:
Application
Filed:
October 24, 2012
Publication date:
October 9, 2014
Applicant:
UNIVERSITY OF EXETER
Inventors:
Richard W. Titball, Sérgio Paulo Fernandes Da Costa, Claire Naylor, Ajit Basak
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