Patents by Inventor Ajit K. Parhi
Ajit K. Parhi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11845742Abstract: Disclosed herein are compounds of formula (I), or a salt thereof and compositions comprising compounds of formula I that exhibit antibacterial activities, when tested alone and/or in combination with a bacterial efflux pump inhibitor. Also disclosed are methods of treating or preventing a bacterial infection in an animal comprising administering to the animal a compound of formula I alone or in combination with the administration of a bacterial efflux pump inhibitor.Type: GrantFiled: November 13, 2018Date of Patent: December 19, 2023Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEYInventors: Edmond J. LaVoie, Hye Yeon Sagong, Ajit K. Parhi
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Publication number: 20230257397Abstract: The invention provides synthetic intermediates and synthetic processes that are useful for preparing the antibacterial agent TXA709:Type: ApplicationFiled: January 31, 2023Publication date: August 17, 2023Applicant: TAXIS PHARMACEUTICALS, INC.Inventors: Sanjeevani GHONE, Fu-An KANG, Nareshkumar JAIN, Ajit K. PARHI, Ravi PONNAIAH, Anil Kumar SONI, Siva Rami Reddy ATHUNURI, Thrisulapani KORRAKUTI, Pullarao SEELAM
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Patent number: 11091498Abstract: Provided herein are compounds of formula (I): and salts thereof. Also provided are pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula (I), and therapeutic methods for treating diseases such as cancer, a bacterial infection or a fungal infection using compounds of formula (I).Type: GrantFiled: April 3, 2017Date of Patent: August 17, 2021Assignee: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Ajit K. Parhi
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Publication number: 20210139508Abstract: The invention provides synthetic intermediates and synthetic processes that are useful for preparing the antibacterial agent TXA709:Type: ApplicationFiled: August 19, 2020Publication date: May 13, 2021Applicant: TAXIS PHARMACEUTICALS, INC.Inventors: Sanjeevani Ghone, Fu-An Kang, Nareshkumar Jain, Ajit K. Parhi, Ravi Ponnaiah, Anil Kumar Soni, Siva Rami Reddy Athunuri, Thrisulapani Korrakuti, Pullarao Seelam
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Publication number: 20200325124Abstract: Disclosed herein are compounds of formula (I), or a salt thereof and compositions comprising compounds of formula I that exhibit antibacterial activities, when tested alone and/or in combination with a bacterial efflux pump inhibitor. Also disclosed are methods of treating or preventing a bacterial infection in an animal comprising administering to the animal a compound of formula I alone or in combination with the administration of a bacterial efflux pump inhibitor.Type: ApplicationFiled: November 13, 2018Publication date: October 15, 2020Inventors: Edmond J. LaVoie, Hye Yeon Sagong, Ajit K. Parhi
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Publication number: 20200325149Abstract: Provided herein are compounds of formula (I): and salts thereof. Also provided are pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula (I), and therapeutic methods for treating diseases such as cancer, a bacterial infection or a fungal infection using compounds of formula (I).Type: ApplicationFiled: April 3, 2017Publication date: October 15, 2020Applicant: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Ajit K. Parhi
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Patent number: 10513528Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare a compound of formula (I): or a salt thereof.Type: GrantFiled: February 23, 2017Date of Patent: December 24, 2019Assignee: Taxis Pharmaceuticals, Inc.Inventors: Ravi Ponnaiah, Sudhakar Sunkari, Anil Kumar Soni, Savi Rami Reddy Athunuri, Thrisulapani Korrakuti, Pullarao Seelam, Ajit K. Parhi
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Publication number: 20190031624Abstract: Disclosed herein are compounds of formula I: or a salt thereof and compositions comprising a compound of formula I or a pharmaceutically acceptable salt thereof. Also disclosed herein are methods for treating or preventing a bacterial infection in an animal comprising administering to the animal a compound of formula I or a pharmaceutically acceptable salt thereof, alone or in combination with a bacterial efflux pump inhibitor.Type: ApplicationFiled: July 26, 2018Publication date: January 31, 2019Inventors: Edmond J. LaVoie, Ajit K. Parhi, Yangsheng Sun
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Patent number: 9950993Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising of compounds of formula I and methods using compounds of formula I.Type: GrantFiled: March 11, 2016Date of Patent: April 24, 2018Assignee: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Gifty A. Blankson, Ajit K. Parhi, Malvika Kaul, Daniel S. Pilch
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Patent number: 9926261Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising of compounds of formula I and methods using compounds of formula I.Type: GrantFiled: March 10, 2016Date of Patent: March 27, 2018Assignee: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Ajit K. Parhi, Gifty A. Blankson, Malvika Kaul, Daniel S. Pilch
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Patent number: 9695135Abstract: The invention provides compounds of formula I: and salts thereof wherein R1-R4 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the compounds or salts, and methods for their use in therapy. The compounds have useful antiviral properties.Type: GrantFiled: May 11, 2015Date of Patent: July 4, 2017Assignee: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Eddy Arnold, Joseph D. Bauman, John E. Kerrigan, Ajit K. Parhi, Kalyan Das, Cody Kelley, Dishaben V. Patel
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Publication number: 20160271082Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising of compounds of formula I and methods using compounds of formula I.Type: ApplicationFiled: March 10, 2016Publication date: September 22, 2016Applicant: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Ajit K. Parhi, Gifty A. Blankson, Malvika Kaul, Daniel S. Pilch
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Publication number: 20160271081Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising of compounds of formula I and methods using compounds of formula I.Type: ApplicationFiled: March 11, 2016Publication date: September 22, 2016Applicant: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Gifty A. Blankson, Ajit K. Parhi, Malvika Kaul, Daniel S. Pilch
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Patent number: 9321781Abstract: The invention provides compounds of formula I: (I) wherein A, B, W, Y, Z, R1, R3 and R4 have any of the meanings defined in the specification and their salts as well as additional compounds and their salts. The invention also provides pharmaceutical compositions comprising a compound of the invention, processes for preparing compounds of the invention, intermediates useful for preparing compounds of the invention, and therapeutic methods for treating cancer, a bacterial infection or a fungal infection using compounds of the invention.Type: GrantFiled: November 4, 2010Date of Patent: April 26, 2016Assignee: Rutgers, The State University of New JerseyInventors: Edmond J. Lavoie, Ajit K. Parhi
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Publication number: 20150322022Abstract: The invention provides compounds of formula I: and salts thereof wherein R1-R4 have any of the meanings defined in the specification, as well as pharmaceutical compositions comprising the compounds or salts, and methods for their use in therapy. The compounds have useful antiviral properties.Type: ApplicationFiled: May 11, 2015Publication date: November 12, 2015Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEYInventors: Edmond J. LaVoie, Eddy Arnold, Joseph D. Bauman, John E. Kerrigan, Ajit K. Parhi, Kalyan Das, Cody Kelley, Dishaben V. Patel
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Publication number: 20120237531Abstract: The invention provides compounds of formula I: (I) wherein A, B, W, Y, Z, R1, R3 and R4 have any of the meanings defined in the specification and their salts as well as additional compounds and their salts. The invention also provides pharmaceutical compositions comprising a compound of the invention, processes for preparing compounds of the invention, intermediates useful for preparing compounds of the invention, and therapeutic methods for treating cancer, a bacterial infection or a fungal infection using compounds of the invention.Type: ApplicationFiled: November 4, 2010Publication date: September 20, 2012Inventors: Edmond J. LaVoie, Ajit K. Parhi
