Patents by Inventor Ajit P. Yoganathan
Ajit P. Yoganathan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10598170Abstract: The devices and systems are medical fluid treatment therapies. The device and systems are configured and capable of operating based on small volumes of fluids. The devices and systems include a pump configured for small volume of a fluid. The pump may include a first conduit configured for inflow of the fluid; a second conduit configured for outflow of the fluid; a fluid chamber configured to move the fluid through the pump; a diaphragm configured to force the fluid through the fluid chamber by indirectly exerting force on the fluid chamber; and a connector configured to removably attach the pump to a motor.Type: GrantFiled: August 4, 2014Date of Patent: March 24, 2020Assignees: Georgia Tech Research Corporation, Emory University, Children's Healthcare of Atlanta, Inc.Inventors: Matthew L. Paden, Ajit P. Yoganathan, Lakshmi Prasad Dasi
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Patent number: 10499949Abstract: Various embodiments of the present invention provide a conduit system including an outer lumen, an inner lumen, and an attaching device. In other embodiments, a multiple access port device adapted for communication with at least one of an outer lumen, an inner lumen, or an attaching device of a conduit system is provided. In yet other embodiments, a system including an inner lumen that is collapsible is provided. Means for closing a conduit system are also provided, including a plug for insertion through an attaching device and a variable radius coiled member associated with an attaching device.Type: GrantFiled: March 18, 2016Date of Patent: December 10, 2019Assignees: Emory University, Georgia Tech Research CorporationInventors: Jorge H. Jimenez, Ajit P. Yoganathan, Seth West, Vinod Thourani
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Patent number: 10463341Abstract: An ultrasonic diagnostic imaging system is described which quantifies regurgitant flow through a plurality of pinhole leaks or a slit leak of a mitral valve. A plurality of orifice locations of a leaking valve are identified and Doppler values obtained from a flow velocity field proximal each orifice. The Doppler values of each flow velocity field vectorially relating to the orifice location are processed to produce a measure of flow through the orifice. The flow measurements for a plurality of such orifices are summed to produce a quantified measure of regurgitant flow through a plurality of pinhole leaks or along a slit leak.Type: GrantFiled: December 15, 2011Date of Patent: November 5, 2019Assignees: Koninklijke Philips N.V., Georgia Tech ResearchInventors: Qifeng Wei, Karl E. Thiele, Ajit P. Yoganathan, Choon-Hwai Yap
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Publication number: 20180296340Abstract: Papillary muscle position control devices, systems, and methods are provided. A papillary muscle position control device generally includes a first anchor, a second anchor, and a support structure. The first anchor can be configured to fixedly connect to an in-situ valve of a heart ventricle. The second anchor can be configured to fixedly connect to a muscle wall of the valve. The support structure can be configured to have an adjustable length and be coupled to the first anchor and second anchor such that adjusting the length of the support structure varies a distance between the first anchor and the second anchor.Type: ApplicationFiled: June 18, 2018Publication date: October 18, 2018Inventors: Ajit P. Yoganathan, Jorge Hernan Jimenez
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Patent number: 10039531Abstract: The cinching apparatus (800) comprising: an anchoring component having a distal end a proximal end; the distal end of the anchoring component having an engaging member (805). A locking component (815) and a tension member (820) wherein the anchoring component is enabled to be positioned on a first target site of a tissue component and the locking component (815) is enabled to be positioned on a second target site of a tissue component of the heart, and the tension member (820) can be coupled to both the anchoring component and the locking component (815) to adjust the distance between the first and second target sites.Type: GrantFiled: December 15, 2006Date of Patent: August 7, 2018Assignee: Georgia Tech Research CorporationInventors: Ajit P. Yoganathan, Jorge Hernan Jimenez
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Patent number: 10010419Abstract: Papillary muscle position control devices, systems, and methods are provided. According to an exemplary embodiment, a papillary muscle position control device generally comprises a first anchor, a second anchor, and a support structure. The first anchor can be configured to fixedly connect to an in situ valve of a heart ventricle. The second anchor can be configured to fixedly connect to a muscle wall of the valve. The support structure can be configured to have an adjustable length and be coupled to the first anchor and second anchor such that adjusting the length of the support structure varies a distance between the first anchor and the second anchor. Other embodiments are also claimed and described.Type: GrantFiled: September 7, 2015Date of Patent: July 3, 2018Assignee: Georgia Tech Research CorporationInventors: Ajit P. Yoganathan, Jorge Hernan Jimenez
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Publication number: 20170042572Abstract: Various embodiments of the present invention provide a conduit system including an outer lumen, an inner lumen, and an attaching device. In other embodiments, a multiple access port device adapted for communication with at least one of an outer lumen, an inner lumen, or an attaching device of a conduit system is provided. In yet other embodiments, a system including an inner lumen that is collapsible is provided. Means for closing a conduit system are also provided, including a plug for insertion through an attaching device and a variable radius coiled member associated with an attaching device.Type: ApplicationFiled: March 18, 2016Publication date: February 16, 2017Inventors: Jorge H. Jimenez, Ajit P. Yoganathan, Seth West, Vinod Thourani
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Patent number: 9320875Abstract: Various embodiments of the present invention provide a conduit system including an outer lumen (810), an inner lumen (805), and an attaching device (820). In other embodiments, a multiple access port device adapted for communication with at least one of an outer lumen, an inner lumen, or an attaching device of a conduit system is provided. In yet other embodiments, a system including an inner lumen that is collapsible is provided. Means for closing a conduit system are also provided, including a plug for insertion through an attaching device and a variable radius coiled member associated with an attaching device.Type: GrantFiled: February 1, 2012Date of Patent: April 26, 2016Assignees: Emory University, Georgia Tech Research CorporationInventors: Jorge Jimenez, Ajit P. Yoganathan, Seth West, Vinod Thourani
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Patent number: 9295553Abstract: An annuloplasty ring, configured for implantation in the annulus of a heart valve, comprising multiple segments each of which are geometrically shaped from a three dimensional perspective to conform to the anatomic shape of the valve annulus. In one embodiment, at least one of the multiple segments of the annuloplasty ring is configured to facilitate a reduction of tension on heart valve tissue and eliminate a substantial portion of potential pressure or force that may be applied to the atrio-ventricular node by the annuloplasty ring when inserted into a heart valve. In another embodiment, at least one of the multiple segments of the annuloplasty ring are configured to include an assembly that facilitates selective adjustment of a segment's respective length and/or shape. The adjustment of the length of one of the ring segment's results in an adjustment of at least one angle between at least one set of other ring segments, thereby causing an adjustment to the geometric characteristics of the ring.Type: GrantFiled: April 7, 2009Date of Patent: March 29, 2016Assignees: Georgia Tech Research Corporation, Emory UniversityInventors: Sai Muralidhar Padala, Ajit P. Yoganathan, Vinod H. Thourani, Jorge H. Jimenez
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Publication number: 20150374494Abstract: Papillary muscle position control devices, systems, and methods are provided. According to an exemplary embodiment, a papillary muscle position control device generally comprises a first anchor, a second anchor, and a support structure. The first anchor can be configured to fixedly connect to an in situ valve of a heart ventricle. The second anchor can be configured to fixedly connect to a muscle wall of the valve. The support structure can be configured to have an adjustable length and be coupled to the first anchor and second anchor such that adjusting the length of the support structure varies a distance between the first anchor and the second anchor. Other embodiments are also claimed and described.Type: ApplicationFiled: September 7, 2015Publication date: December 31, 2015Inventors: Ajit P. Yoganathan, Jorge Hernan Jimenez
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Patent number: 9125742Abstract: Papillary muscle position control devices (900) systems and methods are provided. According to an exemplary embodiment, a papillary muscle position control device generally comprises a first anchor (905), a second anchor (920), and a support structure (915). The first anchor can be configured to fixedly connect to an in situ valve of a heart ventricle. The second anchor can be configured to fixedly connect to a muscle wall of the valve. The support structure can be configured to have an adjustable length and be coupled to the first anchor and second anchor such that adjusting the length of the support structure varies a distance between the first anchor and the second anchor. Other embodiments are also claimed and described.Type: GrantFiled: December 15, 2006Date of Patent: September 8, 2015Assignee: Georgia Tech Research FoundationInventors: Ajit P. Yoganathan, Jorge Hernan Jimenez
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Patent number: 9050189Abstract: An apparatus (100) for and a method of delivering and implanting a surgical device on an anatomic structure is through minimally invasive procedures. The method is facilitated by an apparatus including a unitary tube (106) operatively connected to a deployment head (118) controlled by an apparatus controller. The deployment head is configured to deploy suture hooks or similar clips that connect an annuloplasty implant to heart tissue and secondary surgical devices to the annuloplasty implant. The apparatus is further configured to facilitate orientation adjustment or collapsing of the deployment head and surgical devices attached thereto in order to facilitate their passing through an incision smaller than generally required. After the deployment head passes through the incision its orientation is readjusted so that it may be positioned and the annuloplasty implant automatically sutured to a heart valve annulus by the apparatus suturing sub-assembly using the suture hooks.Type: GrantFiled: December 4, 2009Date of Patent: June 9, 2015Assignee: Georgia Tech Research CorporationInventors: Sai Muralidhar Padala, Ajit P. Yoganathan
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Publication number: 20140341756Abstract: The devices and systems are medical fluid treatment therapies. The device and systems are configured and capable of operating based on small volumes of fluids. The devices and systems include a pump configured for small volume of a fluid. The pump may include a first conduit configured for inflow of the fluid; a second conduit configured for outflow of the fluid; a fluid chamber configured to move the fluid through the pump; a diaphragm configured to force the fluid through the fluid chamber by indirectly exerting force on the fluid chamber; and a connector configured to removably attach the pump to a motor.Type: ApplicationFiled: August 4, 2014Publication date: November 20, 2014Inventors: Matthew L. Paden, Ajit P. Yoganathan, Lakshmi Prasad Dasi
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Patent number: 8834911Abstract: A device for use in combination with a fluid flow having a biologic component and subject to an adverse response to shear stress includes a surface in contact with the flow of the fluid. The surface has a longitudinal direction extending from a leading end toward a trailing end and aligned with a direction of the flow. The surface is susceptible to inducing boundary layer formation within the flow sufficient for a resulting shear stress to induce the response. The surface includes a surface feature sufficient to induce boundary layer tripping in the flow to retard growth of boundary layer formation along the length.Type: GrantFiled: November 15, 2007Date of Patent: September 16, 2014Assignee: Georgia Tech Research CorporationInventors: Ari Glezer, Ajit P. Yoganathan, Lakshmi Prasad Dasi
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Publication number: 20140039375Abstract: Various embodiments of the present invention provide a conduit system including an outer lumen (810), an inner lumen (805), and an attaching device (820). In other embodiments, a multiple access port device adapted for communication with at least one of an outer lumen, an inner lumen, or an attaching device of a conduit system is provided. In yet other embodiments, a system including an inner lumen that is collapsible is provided. Means for closing a conduit system are also provided, including a plug for insertion through an attaching device and a variable radius coiled member associated with an attaching device.Type: ApplicationFiled: February 1, 2012Publication date: February 6, 2014Applicants: GEORGIA TECH RESEARCH CORPORATION, EMORY UNIVERSITYInventors: Jorge H. Jimenez, Ajit P. Yoganathan, Seth West, Vinod Thourani
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Patent number: 8568473Abstract: The present invention describes a cardiac prosthetic system (400) comprising: an anchoring conduit (200) having a harbor (415), the harbor including a first releasably engaging component (515); a temporary valve (305) and a heart valve prosthesis (420) having a second releasably engaging component (445) enabled to be securely coupled and uncoupled from the first releasably engaging component (515) of the harbor (415).Type: GrantFiled: December 15, 2006Date of Patent: October 29, 2013Assignee: Georgia Tech Research CorporationInventors: Ajit P. Yoganathan, Jorge Hernan Jimenez
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Publication number: 20130261458Abstract: An ultrasonic diagnostic imaging system is described which quantifies regurgitant flow through a plurality of pinhole leaks or a slit leak of a mitral valve. A plurality of orifice locations of a leaking valve are identified and Doppler values obtained from a flow velocity field proximal each orifice. The Doppler values of each flow velocity field vectorially relating to the orifice location are processed to produce a measure of flow through the orifice. The flow measurements for a plurality of such orifices are summed to produce a quantified measure of regurgitant flow through a plurality of pinhole leaks or along a slit leak.Type: ApplicationFiled: December 15, 2011Publication date: October 3, 2013Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Qifeng Wei, Karl E. Thiele, Ajit P. Yoganathan, Choon-Hwai Yap
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Publication number: 20130030523Abstract: An annuloplasty ring, configured for implantation in the annulus of a heart valve, comprising multiple segments each of which are geometrically shaped from a three dimensional perspective to conform to the anatomic shape of the valve annulus. In one embodiment, the annuloplasty ring is configured to facilitate a reduction of tension on heart valve tissue and eliminate a substantial portion of potential pressure or force that may be applied to the atrioventricular node by the annuloplasty ring when implanted. In another embodiment, at the annuloplasty ring is configured to include an assembly that facilitates selective adjustment of a segment's respective length and/or shape. The adjustment of the length of one of the ring segment's results in an adjustment of at least one angle between at least one set of other ring segments, thereby causing an adjustment to the geometric characteristics of the ring.Type: ApplicationFiled: April 7, 2009Publication date: January 31, 2013Applicants: Emory University, Georgia Tech Research CorporationInventors: Sai Muralidhar Padala, Ajit P. Yoganathan, Vinod H. Thourani, Jorge H. Jimenez
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Patent number: 8206594Abstract: A novel system and method for fluid management for accurate continuous venovenous hemofiltration (CWH) in extracorporeal membrane oxygenation (ECMO). The fluid management or CWH system is automated and configured for operation as a stand alone unit and can be easily integrated with an ECMO system. The fluid management system is capable of producing either perfect or negative fluid balance between ultrafiltrate removal and replacement fluid delivery. The fluid management system can achieve electrolyte replacement over a range of flow rates needed to care for patients ranging from neonates to adults. Finally, the novel fluid management system preserves patient safety, maintains sterility during operation, is easy to operate, and is compact enough to fit near a patient's bed.Type: GrantFiled: June 6, 2008Date of Patent: June 26, 2012Assignees: Emoery University, Children's Healthcare of Atlanta, Georgia Tech Research CorporationInventors: James D. Fortenberry, Ajit P. Yoganathan, Philippe Sucosky, Lakshmi Prasad Dasi, Matthew L. Paden
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Publication number: 20110301701Abstract: An apparatus (100) for and a method of delivering and implanting a surgical device on an anatomic structure is through minimally invasive procedures. The method is facilitated by an apparatus including a unitary tube (106) operatively connected to a deployment head (118) controlled by an apparatus controller. The deployment head is configured to deploy suture hooks or similar clips that connect an annuloplasty implant to heart tissue and secondary surgical devices to the annuloplasty implant. The apparatus is further configured to facilitate orientation adjustment or collapsing of the deployment head and surgical devices attached thereto in order to facilitate their passing through an incision smaller than generally required. After the deployment head passes through the incision its orientation is readjusted so that it may be positioned and the annuloplasty implant automatically sutured to a heart valve annulus by the apparatus suturing sub-assembly using the suture hooks.Type: ApplicationFiled: December 4, 2009Publication date: December 8, 2011Applicant: GEORGIA TECH RESEARCH CORPORATIONInventors: Sai Muralidhar Padala, Ajit P. Yoganathan