Patents by Inventor Ajith A. Welihinda

Ajith A. Welihinda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA encoding the novel mammalian protein, Ire1p
    Patent number: 7439061
    Abstract: A novel polynucleotide encoding a mammalian bifunctional protein kinase\endoribonuclease referred to herein as hIre1p, is provided. hIre1p is expressed in the endoplasmic reticulum (ER) and upregulates the transcription of genes encoding ER protein chaperones, such as, but not limited to, glucose-related proteins (GRP's). Therapeutic, diagnostic and research methods employing the polynucleotide and protein are also provided.
    Type: Grant
    Filed: July 14, 2004
    Date of Patent: October 21, 2008
    Assignee: The Regents of the University of Michigan
    Inventors: Randal J. Kaufman, Witoon Tirasphon, Ajith A. Welihinda
  • Ire1p, novel mammalian protein, and gene encoding same
    Publication number: 20050059052
    Abstract: A novel polynucleotide encoding a mammalian bifunctional protein kinase\endoribonuclease referred to herein as hIre1p, is provided. hIre1p is expressed in the endoplasmic reticulum (ER) and upregulates the transcription of genes encoding ER protein chaperones, such as, but not limited to, glucose-related proteins (GRP's). Therapeutic, diagnostic and research methods employing the polynucleotide and protein are also provided.
    Type: Application
    Filed: July 14, 2004
    Publication date: March 17, 2005
    Inventors: Randal Kaufman, Witoon Tirasophon, Ajith Welihinda