Patents by Inventor Ake Lundwall

Ake Lundwall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5432264
    Abstract: A recombinant cystatin C polypeptide or a derivative thereof, such as 3-des-hydroxy-cystatin C, is produced biosynthetically by fermentation of a microorganism into which plasmids containing a DNA-sequence coding for said polypeptide have been introduced. Preparations containing recombinant cystatin C, preferably 3-des-hydroxy-cystatin C, have a higher cystein proteinase inhibitor activity than native cystatin C, isolated from human fluids. Such preparations are useful in therapeutic treatments of patients suffering from different diseases, for example herbes simplex.
    Type: Grant
    Filed: August 13, 1992
    Date of Patent: July 11, 1995
    Assignee: Novo Nordisk A/S
    Inventors: Anders Grubb, Ake Lundwall, Magnus Abrahamson, Henrik Dalboge
  • Patent number: 5258288
    Abstract: Disclosed are a transformed mammalian cell that produces biologically active Protein S, and a vector for effecting the transformation of the cell. produces biologically active human Protein S, and the vector used to effect the transgenesis of the cell. The vector disclosed includes DNA encoding mature human Protein S, under the transcriptional control of a eukaryotic metallothionein gene, and also includes the transforming region of the bovine papilloma virus genome, and a fragment of SV40 DNA.
    Type: Grant
    Filed: July 25, 1986
    Date of Patent: November 2, 1993
    Assignee: Genzyme Corporation
    Inventors: Robert Wydro, Edward Cohen, William Dackowski, Johan Stenflo, Ake Lundwall, Bjorn Dahlback