Patents by Inventor Akemi Kakino

Akemi Kakino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230288437
    Abstract: The present invention provides a method for quantifying modified HDL contained in a sample, comprising binding a modified HDL to a modified HDL-binding protein, and quantifying a complex of the modified HDL-binding protein and the modified HDL, wherein the modified HDL-binding protein comprises a protein having a sequence of an L chain region of Factor V, or a variant thereof.
    Type: Application
    Filed: March 29, 2021
    Publication date: September 14, 2023
    Inventors: Tatsuya Sawamura, Akemi Kakino
  • Publication number: 20230243855
    Abstract: The present invention provides a method for quantifying adiponectin including quantifying adiponectin while distinguishing between an adiponectin having physiological activity and an adiponectin having pathological activity in a quantification of adiponectin in body fluid.
    Type: Application
    Filed: March 3, 2021
    Publication date: August 3, 2023
    Inventors: Tatsuya SAWAMURA, Akemi KAKINO
  • Publication number: 20230232881
    Abstract: The present invention provides an oil-or-fat processed starch that has exceptional performance when used as a raw ingredient of a coating for fried foods, etc. The oil-or-fat processed starch is characterized in that the amount of carbohydrates having a degree of polymerization of 1-3 in the sugar composition of a water-soluble fraction of an aqueous suspension is 3-20 mass %. A coating for fried foods according to the present invention is characterized by containing the aforementioned oil-or-fat processed starch. A method for producing a coating for fried foods according to the present invention is characterized in that the aforementioned oil-or-fat processed starch is added as a raw ingredient of a coating for fried foods. Moreover, a method for producing fried foods according to the present invention is characterized in that the aforementioned coating for fried foods is bonded to a main ingredient and then subjected to an oil-heating treatment.
    Type: Application
    Filed: April 16, 2020
    Publication date: July 27, 2023
    Applicant: NIHON SHOKUHIN KAKO CO., LTD.
    Inventors: Nobuhito IGARASHI, Misa HIRANO, Akemi KAKINO, Raiki YAMAMOTO, Hitoshi TAKAGUCHI
  • Publication number: 20220089686
    Abstract: A fusion protein being a lipid-free reference standard having good long-term storability, which is used for measuring the quantity or quality of modified HDL, and a method for accurately, repeatability and reliably measuring high-density lipoprotein using the same. In the fusion protein, a complete protein sequence or partial fragment protein sequence for ApoA I is linked directly or via a spacer to a LOX-1 binding protein sequence that binds to a lectin-like oxidized LDL receptor: LOX-1. The method for measuring a modified high-density lipoprotein in a test sample is a method for measuring a modified high-density lipoprotein through binding of the modified high-density lipoprotein to LOX-1 and an anti-APOA I antibody, wherein, using the fusion protein as a reference standard for the modified high-density lipoprotein, the modified high-density lipoprotein in the test sample is determined by comparison with the reference standard through optical detection and/or radiation dosage detection.
    Type: Application
    Filed: February 13, 2019
    Publication date: March 24, 2022
    Applicant: SHINSHU UNIVERSITY
    Inventors: Tatsuya SAWAMURA, Akemi KAKINO
  • Publication number: 20180186877
    Abstract: The present invention provides an anti-blood coagulant capable of selectively suppressing a pathological blood coagulation reaction without increasing the risk of major bleeding. The anti-blood coagulant in accordance with the present invention includes a binding inhibiting component that inhibits the binding of LOX-1 to at least one of factor V and factor Va.
    Type: Application
    Filed: February 20, 2018
    Publication date: July 5, 2018
    Inventors: Tatsuya SAWAMURA, Yoshiko FUJITA, Akemi KAKINO
  • Publication number: 20170015744
    Abstract: The present invention provides an anti-blood coagulant capable of selectively suppressing a pathological blood coagulation reaction without increasing the risk of major bleeding. The anti-blood coagulant in accordance with the present invention includes a binding inhibiting component that inhibits the binding of LOX-1 to at least one of factor V and factor Va.
    Type: Application
    Filed: December 23, 2014
    Publication date: January 19, 2017
    Inventors: Tatsuya SAWAMURA, Yoshiko FUJITA, Akemi KAKINO
  • Publication number: 20150335710
    Abstract: The present invention provides an oxidized LDL inhibitor that is capable of (i) binding specifically to oxidized LDL, (ii) suppressing the physiological activity of oxidized LDL, and (iii) inhibiting the uptake of oxidized LDL into cells. The oxidized LDL inhibitor according to the present invention contains a Del-1 protein as an active ingredient. The Del-1 protein consists, for example, of the amino acid sequence of SEQ ID NO: 1.
    Type: Application
    Filed: August 6, 2015
    Publication date: November 26, 2015
    Inventors: Tatsuya Sawamura, Akemi Kakino
  • Publication number: 20140378659
    Abstract: The present invention provides an oxidized LDL inhibitor that is capable of (i) binding specifically to oxidized LDL, (ii) suppressing the physiological activity of oxidized LDL, and (iii) inhibiting the uptake of oxidized LDL into cells. The oxidized LDL inhibitor according to the present invention contains a Del-1 protein as an active ingredient. The Del-1 protein consists, for example, of the amino acid sequence of SEQ ID NO: 1.
    Type: Application
    Filed: February 7, 2013
    Publication date: December 25, 2014
    Inventors: Tatsuya Sawamura, Akemi Kakino